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báo cáo khoa học: " The role of business in addressing the long-term implications of the current food crisis" docx

Báo cáo khoa học:

Báo cáo khoa học: "Clostridium difficile-associated diarrhea in radiooncology: an underestimated problem for the feasibility of the radiooncological treatment" doc

... feasibility of the radiooncological therapy in terms of interruption orabandonment of the radiotherapy, change of therapyconcept and the effect on the feasibility of chemother-apy were evaluated.Induced ... onepatient of 484 in 2006 (incidence 0,2%), 16 of 398 in 2007 (4,0%), 11 of 423 in 2008 (2,6%), 4 of 384 in 2009(1,0%) and 2 of 461 in 2010 (0,4%).Complications of CDAD The effect of CDAD on ... have an interruption of radiotherapy.42% o f the patients developing a CDAD need a pause of the radiation. For those patients who have an inter-ruption of the radiotherapy, the average interruptiontime...
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Tài liệu Báo cáo khoa học: Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase) doc

Tài liệu Báo cáo khoa học: Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase) doc

... bonding between the imidazole nitrogen of the conserved His and the hydroxyl of the active-siteSer increases the nucleophilicity of the Ser oxygen,facilitating attack of the hydroxy group on the ... 2B). A closer view of the axial canal in the center of the spicule reveals local-ization of silicatein in the axial filament as well aswithin the silica shell surrounding the spicule(Fig. 2C). ... bonds, the concentration of the released product p-aminophenol was determinedat a wavelength of 300 nm, which is in the trailingedge of the main absorption bands under the condi-tions used. Another...
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Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf

Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf

... Ca2+peak)resulted in an almost immediate abolition of the remaining part of the Ca2+signal, which then reached the level as in platelets preincubated with AR-C. In the experiments, a concentration of 2–5 ... another 25%, thusindicating the additional involvement of PKA. Toassess more directly the role of the P2Y12⁄ PI3-Kbpathway in procoagulant activity, effects of ADP onphosphatidylserine ... that neither wortmanninnor TGX221 affected thrombin generation in the pres-ence of AR-C (not shown). With only wortmanninpresent, the PKA inhibitor H89 further reduced the rate of thrombin generation...
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Báo cáo khoa học: Inter-flavin electron transfer in cytochrome P450 reductase – effects of solvent and pH identify hidden complexity in mechanism potx

Báo cáo khoa học: Inter-flavin electron transfer in cytochrome P450 reductase – effects of solvent and pH identify hidden complexity in mechanism potx

... NADPH. In the fol-lowing, a synopsis of the gathered results is used tosupport the hypothesis that the blue di-sq is kineticallyless exposed at elevated pH. The protonation state of the N5 in the ... oxidoreductase. The role of cysteine 566 in catalysis and cofactor binding. J BiolChem 266, 19976–19980.26 Shen AL & Kasper CB (1995) Role of acidic residues in the interaction of NADPH–cytochrome ... the inter-flavinET reactions, so the pH dependence of the kineticbehaviour at 600 nm was analysed, reporting on the formation of the blue, neutral sq species of the FMNand the FAD cofactors. Redox...
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Báo cáo khoa học: Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of b-oxidation doc

Báo cáo khoa học: Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of b-oxidation doc

... diverse roles in the cellular life cycle.Indeed, lipid droplets are involved in the maintenance of intracellular cholesterol balance in fibroblasts [12]and appear to be the principal source of fatty ... elevatedamounts of adipophilin, may explain to some extent the increased storage of lipids.To examine the effect of adipophilin on TG synthe-sis, Ad.CMV.adipophilin- and Ad.CMV.GFP-infectedmacrophages ... fetal bovine serumshowed a quasi absence of lipid droplets in the cyto-plasm following Oil Red O staining (Fig. 5A,C,I).However, incubation of adipophilin-infected macro-phages in RPMI-1640...
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Báo cáo khoa hoc:

Báo cáo khoa hoc:" Selection for litter size in pigs. II. Efficiency of closed and open selection lines" ppt

... against an increase of 64% in the dam-son pathway.3.4. Probability of origin of genes and inbreeding In the line selected since G11, hyperprolific genes entered via the regularimmigration of hyperprolific ... prolific genes in the sows of the last generation. In the control line, the inbreeding coefficient of sows increased to about 10percent in G11, as also shown in Bolet et al. [2]. In SL, it reached ... representing the gain over the remainingnine generations (from G7 to G16), i.e. 9/16 of the total gain. The presentestimates agree rather closely with the least-squares estimates over the G0–G11...
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báo cáo khoa học:

báo cáo khoa học: "Multiple infarcted regenerative nodules in liver cirrhosis after decompensation of cirrhosis: a case series" pdf

... performed the histological examination of the liver nodules. All authors read and approved the final manuscript.Competing interests The authors declare that they have no competing interests.Received: ... as single casereports [1-4]. Kim et al. pointed out that especially in patients with a history of substantial gastrointestinalbleeding, infarcted regenerativ e nodules must beincluded in the ... of such lesions is known tobe different from that of regenerating nodules, showinghigh signal intensity on T2-weighted spin-echo MRimages. Thus, these lesions can have different findingsin...
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Báo cáo khoa học: Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding docx

Báo cáo khoa học: Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding docx

... BM3,whereNADP(H) binding to the reductase domain is thought toinduce significant changes in the reduction potentials of the FAD[34].WeconcludethatinthecaseofCPRtheobserved effects of the binding of coenzyme ... dithio-nite [28], indicating that the potential of the flavin couples is the sole determinant of the redox equilibrium within the enzyme under these conditions, and hence of the nature of the equilibrium ... fold. The different structuraldomains are indicated. The FAD-domain contains the binding site forNADPH and is related to the FNR family of flavoproteins. For clarity, the NADPH-binding subdomain...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt

Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt

... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati,OH, USA) constantly maintained at 1% O2. Culturemedium ... lgÆmL)1insulin, 1 lm dexamethasone, and0.5 mm IDM). Cells were then maintained in DMEM con-taining 10% fetal bovine serum and 1 lgÆmL)1insulin. The medium was replaced every other day. ... cultured in DMEM containing 10% fetal bovineserum. OP9 cells were grown in aMEM containing 20%fetal bovine serum. C2C12 cells were maintained in DMEMcontaining 10% fetal bovine serum.Adipogenic...
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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx

Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx

... thusblocking protein synthesis and leading cells to death. The current model proposed for the mechanism of antitumouraction of BS-RNase is based on the ability of the proteinto resist the neutralizing ... plateau.These data indicate that the cell sulfhydryls responsiblefor the exchange with the protein disulfides are located in the plasma membrane. Furthermore, they show that, asproposed in the hypothesis ... hypothesize that the cytotoxicactivity of the latter monomers was due to the presence in these proteins of disulfide bonds, with their potentialchemical instability. It is well known that in the...
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