Microvascular Research biology and pathology - part 3 pptx

... indanyloxyacetic acid; 9-AC, 9-anthracenecarboxylic acid; NPPB, 5-nitro- 2-( 3- phenyl- propylamino)benzoic acid. e —, Not present; ?, present, but specific isoform unclear, or mechanism unclear. 236 PART I Basic ... transmonolayer endothelial resistance (TER) and increased fluid and solute translocation [1]. Nonskeletal-muscle MLCK exists as high-molecular-weight (~210kDa) and low...

Ngày tải lên: 11/08/2014, 13:20

... 97 8-0 -1 2-6 39 51 0-5 (set) ISBN 10: 0-1 2-6 39 51 0-1 (set) ISBN 10: 0-1 2-6 39 511-X (Volume 1) ISBN 13: 97 8-0 -1 2-6 39 51 1-2 (Volume 1) ISBN 10: 0-1 2-6 39 51 2-8 (Volume 2) ISBN 13: 97 8-0 -1 2-6 39 51 2-9 (Volume 2) For all ... Center, Shreveport, LA 71 13 0 -3 932 Abu-Bakr Al-Mehdi Department of Pharmacology, College of Medicine, Uni- v...

Ngày tải lên: 11/08/2014, 13:20

... collagen stabi- lization. In mammals, three homologs termed HPH-1, -2 , and -3 have been cloned, constituting the superfamily of dioxygenases, and require molecular oxygen and 2-oxoglu- tarate as ... identical to factor-inhibiting hypoxia-inducible factor-1 (FIH-1), which was initially identified by Semenza and coworkers as a novel HIF-1-binding protein. This enzyme is a 2-oxoglu-...

Ngày tải lên: 11/08/2014, 13:20

... 729 promote angiogenesis. The 15-LOX isoenzymes (15-LOX- 1, 15-LOX-2) convert arachidonic acid to 15-S-HETE and linoleic acid to 1 3- S-hydroxy-9,11-octadecadienoic acid ( 1 3- S-HODE). These substances ... migration and angiogene- sis in vivo and may result in increased endothelial cell sur- vival. In addition, the product of 12-LOX, 12-S-HETE, 15-LOX-2 12-S-LOX 12-R-LOX 8-LOX 5-LOX Ar...

Ngày tải lên: 11/08/2014, 13:20

... growth factor-a (TGF-a), transforming growth factor-b (TGF-b), hepatocyte growth factor, tumor necrosis factor-a (TNF-a), prostaglandin E 2 (PGE 2 ), angio- genin, and interleukin-8 (IL-8), VEGF ... VEGF-A, PlGF, VEGF-B, VEGF-C, VEGF-D, and VEGF-E. VEGF- Definition Vascular Endothelial Growth Factor (VEGF) is consid- ered to be a potent inducer of vascular permeability and angiogenesis...

Ngày tải lên: 11/08/2014, 13:20

... (30 % adenocarcinoma, 40% squamous cell carcinoma, and 30 % large cell carci- noma and other types). In univariate analysis, T-stage, N- stage, and growth pattern predicted overall and disease-free survival. ... five PDGF isoforms: PDGF-AA, -AB, -BB, -CC, and -DD. These isoforms exert their effects by activating two protein tyrosine kinase receptors, denoted the a-receptor and b-r...

Ngày tải lên: 11/08/2014, 13:20

... platelets, and fresh-frozen plasma (FFP) or cryoprecipitate (Table 10 7-2 ). Whole blood is first separated into PRBCs and platelet-rich plasma by slow centrifugation. The platelet-rich plasma ... blood can be safely transfused to an Rh-negative patient who lacks anti-D; however, the recipient is likely to become alloimmunized and produce anti-D. Rh-negative women of childbearing...

Ngày tải lên: 07/07/2014, 04:20

... geographies, and services (see Tables 6-2 and 6 -3 , Figure 6-7 ). This included the addition of Chase’s non- investment grade clients, middle-market clients, and clients engaged in 3. As quoted in Andrew ... Pro-forma Revenues and Pretax Cash-flow, 1999 ($ billions) 1 Revenues Pretax Cash Earnings Investment banking $15.9 $5.9 Wealth management 3. 7 1.0 Private equity 3. 4 3...

Ngày tải lên: 26/01/2014, 11:20

... 1 234 56789101112 131 41516171819202122 23 14 - 15 13 - 14 12 - 13 11 - 12 10 - 11 1-1 0 8-9 7- 8 6-7 5-6 1-5 3- 4 2 -3 1-2 P N M L K J H G F E D C B A Node no. Days 12A 23B 3 4,7C 15 D 56 E 6 7, 13 F 78 G 8 ... 13. 7 S 1 2 6 7 17 1 23 24 21 33 37 1 11 3 4 1 8 9 10 1 14 16 20 1 21 26 28 30 34 35 36 F 2 3 7 8 18 20 24 25...

Ngày tải lên: 26/01/2014, 11:20

... Vibration, Human Movement and Flow Induced Vibration 37 2.5 .3 Bi-stable structures Ramlan (2009) also studied bi-stable structures for energy harvesting (also termed the snap- through mechanism). ... power of 0.2mW, 2mW and 5mW under the wind of 3. 5m·s -1 , 5.5m·s -1 and 7.5m·s -1 respectively (Windbelt, 2004). Kim et al (2009) reported a small-scale version of...

Ngày tải lên: 19/06/2014, 08:20