báo cáo khoa học: "Gene-expression and network-based analysis reveals a novel role for hsa-mir-9 and drug control over the p38 network in Glioblastoma Multiforme progression" ppsx

... Pathway Interaction Database (PID) [12]. We Gene-expression and network- based analysis reveals a novel role for hsa-mir-9 and drug control over the p38 network in Glioblastoma Multiforme progression ... MAPKAP kinases Tamoxifen ESR1 Signaling mediated by p38- alpha and p38- beta pathway Six out of the 69 drugs in The Cancer Genome Atlas (...

Ngày tải lên: 11/08/2014, 12:21

... used as a spice and coloring agent in Indian food, as well as a therapeutic agent in traditional Indian medicine. Enthusiasm for curcumin as an anti-can- cer agent evolved based on the wealth ... - ravira@jhmi.edu; Collins Karikar - ckarika1@jhmi.edu; Amarnath Maitra - maitraan@yahoo.co .in; Anirban Maitra* - amaitra1@jhmi.edu * Corresponding author Abstract Background: Curcum...

Ngày tải lên: 11/08/2014, 00:22

... coenzyme analog lacking the ade- nine ring in the upper axial ligand; a model of damaged cofactors) for free adeninylpentylcobalamin (AdePeCbl) (an inactive coenzyme analog containing the adenine ring ... the enzymeÆreactivase complex was formed in small amounts from apoenzyme and the reactivase and not at all from the enzymeÆCN-Cbl complex and the reactivase (data...

Ngày tải lên: 15/02/2014, 01:20

... indicate an important role for the C-terminal domain in catalysis. The compari- son between Ub-AMC and Ub-K-TAMRA, revealed more pronounced differences in the catalytic efficiency of the variants ... expression in mammalian cells had an N-terminal 3XFLAG tag and a C-terminal Myc tag. USP7-FL con- structs used for proteomics analysis contained either N- or C-termi- n...

Ngày tải lên: 07/03/2014, 05:20

... suggesting that GBE50 prevented the harm caused by an HFD. In addition, we found no significant alterations in the levels of alanine aminotransferase, aspartate amino- transferase or creatinine kinase ... product that matches the standardized German product as EGb761. GBE50 is approved by the China State Food and Drug Administra- tion (SFDA) and is used clinically in China....

Ngày tải lên: 16/03/2014, 04:20

... patient values for almost all health states. Differences among the three study groups are substantially greater for the TTO data than for the rank and VAS data. Furthermore, the TTO values for ... integrated the TTO study protocol, scoring administration, and the visual aid. The program presented the standardized health states (including the patient’s health stat...

Ngày tải lên: 12/08/2014, 01:22

... than most amino acids. The concentration of asparagine also increased in Pseudomonas syringae-infected tomato leaves, suggesting that asparagine, and not glutamine is primarily involved in the ... a halotolerant-alanine betaine accumulating Plum- baginaceae. Plant Physiol Biochem 2003, 41:993-998. 47. Rathinasabapathi B: Propionate, a source of beta-alanine, is an inhibitor of b...

Ngày tải lên: 12/08/2014, 05:20

... the kinetic parameters t hat enable such oscillations. The main result of such an analysis is that oscillations arise if t he parameter k 3 is the l argest and the parameters k 6 and k 7 are the ... values and a 3 < 0 in the unstable steady state, oscillations can be obtained. Analysis of negative and positive subgraphs and comparison of their values gives ris...

Ngày tải lên: 19/02/2014, 16:20

... empirically attested in corpus data. We automatically acquire alternating verbs from large balanced corpora by using partial- parsing methods and taxonomic information, and discuss how corpus data ... percentages are the aver- age of the judges' individual classifications. 399 Acquiring Lexical Generalizations from Corpora: A Case Study for Diathesis Alternations Ma...

Ngày tải lên: 20/02/2014, 19:20

... 2007. c 2007 Association for Computational Linguistics Grammar Approximation by Representative Sublanguage: A New Model for Language Learning Smaranda Muresan Institute for Advanced Computer ... propose a new language learning model that learns a syntactic-semantic grammar from a small number of natural language strings annotated with their semantics, along with basic assumptio...

Ngày tải lên: 08/03/2014, 02:21