báo cáo khoa học: "Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment" pptx

... 3:64 http://genomemedicine.com/content/3/10/64 Page 3 of 12 RESEARCH Open Access Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment Wendy Lorizio 1,2,3* , Hope ... the impact of pharmacogenetic test results on patient and clinician choice of therapy. CYP2D6 testing amo ng tamoxifen users offers a potential test case of...

Ngày tải lên: 11/08/2014, 12:21

... should concern a choice of verb features with respect to the specific properties of the desired verb clas- sification. We could think of either (i) performing several cluster analyses on the same set of verbs, but ... Germany schulte@ims.uni—stuttgart.de Abstract The choice of verb features is crucial for the learning of verb classes. This pa- per presents clustering experimen...

Ngày tải lên: 17/03/2014, 22:20

... Number of genes Number of genes Number of genes Number of genes Fig. 5. Left column: cross-validation of the seed distribution method for six different transcription factors. By means of a jack- knife ... the case of c-Myc, the broad-spectrum ontologies [34]. The results of this jack-knife procedure also provide an estimate of how many of the true positives will lie in...

Ngày tải lên: 18/02/2014, 18:20

... funded by the Of ce of the Di- rector of National Intelligence (ODNI), Intelligence Advanced Research Projects Activity (IARPA), through the U.S. Army Research Lab. All state- ments of fact, opinion ... hypotheses of latent vectors for the definition of bank#n#1 2 Learning Latent Semantics of Definitions 2.1 Intuition Given only a few observed words in a definition, there are many h...

Ngày tải lên: 19/02/2014, 19:20

... Proceedings of the 45th Annual Meet- ing of the Association of Computational Linguistics, ACL’07, pages 760–767. Anders Søgaard. 2011. Semi-supervised condensed nearest neighbor for part -of- speech ... Yoram Singer. 2003. Feature-Rich Part -of- Speech Tagging with a Cyclic Dependency Network. In Proceedings of the Annual Conference of the North American Chapter of the Associatio...

Ngày tải lên: 19/02/2014, 19:20

... the constructs produce proteins of the expected masses, we attached the V5 epitope to the C terminus of the CRFR1 isoforms (Fig. 1C). The predicted masses of the isoforms without/with V5 tag are ... for artificial construct pCRFR1h2, where instead of a band with 53 kDa a Fig. 1. The structure of CRFR1 isoforms. (A) Alternatively spliced isoforms of CRFR1. Shaded boxes, translated e...

Ngày tải lên: 07/03/2014, 15:20

... [35] of the mul- tiple sequence alignment of human G-CSF and its orthologous proteins. It consists of stacks of symbols, one for each position in the protein sequence; the overall height of the ... of selected glutamines. (A–D) Plots corre- sponding to Gln131 and Gln134 in the MD simulation of the wild type and of Gln131 and Gln132 in the simulation of Mut4, respec- tively....

Ngày tải lên: 16/03/2014, 00:20

... phosphorylation of substrates could prove the concept of dual inhibitor sensitivity. This is important not only from a biochemical point of view, because the one-off auto- activation mechanism of the ... regulation of DYRK1A by interacting proteins. Binding of 14-3-3b to an autop- hosphorylated serine residue in the C-terminal domain of DYRK1A (Ser529, numbered Ser520 in the sho...

Ngày tải lên: 22/03/2014, 16:21

... assembly ⁄ disassembly of microtubules by interacting with a and bc subunits of G proteins. Lipid modification of G protein sub- units, i.e. the myristoylation of Ga and prenylation of Gc, are expected ... particularly dynamic [85]. Many functions of Go are thought to be mediated through the actions of a common pool of Gbc dimers. Based on the observed role of G protein subun...

Ngày tải lên: 30/03/2014, 10:20

... Litsenburg et al. Health and Quality of Life Outcomes 2011, 9:25 http://www.hqlo.com/content/9/1/25 Page 4 of 7 RESEARC H Open Access Impaired sleep affects quality of life in children during maintenance ... litsenburg@vumc.nl 1 Department of pediatrics, VU University Medical Center, Amsterdam, Netherlands Full list of author information is available at the end of the article va...

Ngày tải lên: 20/06/2014, 15:20