báo cáo khoa học: "Genomic and stem cell policy issues: more alike than different?" pptx

... Stat. 524, 803. 2. Levine AD: Policy uncertainty and the conduct of stem cell research. Cell Stem Cell 2011, 8:132-135. 3. Adams A: Stem cell cures? The long and winding road. Stanford Medicine ... in genomics and human genetics. Annu Rev Genomics Hum Genet 2010, 11:383-425. doi:10.1186/gm251 Cite this article as: Majumder MA: Genomic and stem cell policy issu...

Ngày tải lên: 11/08/2014, 12:21

... metastatic behaviour in a CRC cell [55]. Hsp27 is a cytoprotective chaperone that is phosphoacti- vated during cell stress that prevents aggregation and/ or regulates activity and degradation of certain ... D) and 49 controls. The second set consisted of samples from 37 CRC patients and 31 healthy controls. They reported three potential biomarkers with a sensitivity and specifi-...

Ngày tải lên: 09/08/2014, 04:21

... average error in the KIE for this data set is ±5% and the minimum and maximum error is 1% and 18%, respectively. Hydrogen tunnelling in biological systems S. Hay et al. 3936 FEBS Journal 276 (2009) ... [4,13,14] and flavo- protein [8,15–20] systems. Using a combination of experimental and computational approaches, we have shown that H-transfer reactions can occur by ‘deep’ tunnelling...

Ngày tải lên: 18/02/2014, 11:20

... units higher than obtained in the equilibrium binding studies [18] and 1 pH unit lower than the pK a for the e-amino group of lysine in solution [28]. This discrepancy between the results in [18] and ... all temperatures studied with a rate constant more than 10-fold higher than sealing of the complementary ndsDNA. Both adenylation of T4 DNA ligase and sealing of the complemen...

Ngày tải lên: 21/02/2014, 00:20

... standard enzyme assay, and growth complementation and kinetic parameters were evaluated. All Asp31 substitutions affected enzyme func- tion; D31E, D31Q and D31N reduced activity by 80–90%, and ... L32D mutant was 0.84 lm, and therefore almost two-fold lower than that of the wild type. The wild type and the L32F and L32A mutants had V max (NADPH) val- ues of 80, 69.6 and 53.5...

Ngày tải lên: 16/03/2014, 10:20

... Ballas and Franca B. Barton drafted the manuscript. Franca B. Barton, Myron A. Waclawiw, and Michael L. Terrin performed the statistical analyses and interpreted the results. James R. Eckman and ... sickle cell disease: rates and risk factors. N Engl J Med 1991, 325:11-16. 6. Farber MD, Koshy M, Kinney TR, the Cooperative Group: Cooper- ative study of sickle cell disease: demogr...

Ngày tải lên: 20/06/2014, 15:20

... August [21,41]. The warmer and more moist conditions of the summer months may favor the survival and growth of STEC [21]. More sampling was conducted during summer season, more E. coli O157:H7 ... on their band numbers. Using two primers CRA22 and CRA23 at least 7 bands were generated except 4 strains. Moreover, the discriminatory power ( D -value) revealed 0.86. These diverse b...

Ngày tải lên: 07/08/2014, 18:21

... expression profiles, phenolics and lignin of Sitka spruce bark and sapwood before and after wounding and inoculation with Heterobasidion annosum. Physiological and Molecular Plant Pathology ... 2), which is shorter than expected due to technical problems in the cDNA synthesis and library preparation. Also we used Newbler 2.3 to assemble this data set and Kumar and Blaxte...

Ngày tải lên: 11/08/2014, 11:21

... physiological and pathological responses, such as oligodendrocyte cell differentiation [3], epigenetic modi- fication [4] and DNA damage response [5], as well as embryonic stem cell function and fate ... MEK1 expression, and leads to the repression of cell prolifera- tion during megakaryocytic differentiation in K562 cells [21]. In addition, miR-34c is induced under the control...

Ngày tải lên: 14/02/2014, 19:20

... are easily obtainable and expandable, multipotent progeni- tor cells [1] that have emerged as attractive candidates for cellular therapies for heart and other organ-system disorders [2]. Although ... mesenchymal stem cells. Science 284, 143–147. 2 Porada CD, Zanjani ED & Almeida-Porad G (2006) Adult mesenchymal stem cells: a pluripotent population with multiple applications. Curr...

Ngày tải lên: 18/02/2014, 04:20