báo cáo khoa học: "Genome Medicine: stem cells, genomics and translational research" pptx

... use of specific cell types produced from human © 2010 BioMed Central Ltd Genome Medicine: stem cells, genomics and translational research Stuart H Orkin* E D I T O R I A L *Correspondence: stuart_orkin@dfci.harvard.edu ... articles on stem cell genomics to be published in this and upcoming issues of Genome Medicine. ese contributions sample just a few of the many excitin...

Ngày tải lên: 11/08/2014, 12:21

... leukemia, burns and spinal-cord injury. Both adult and ES cells can be used for stem cell therapy. In this review, we describe the derivation and characterization of ES cells and cloned ES cells. ... blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood island and myocardium. J Embryol Exp Morphol 1985, 87, 27-45. 17. Draper JS, Moore HD, Ruban LN,...

Ngày tải lên: 07/08/2014, 18:21

... somatic stem cells, using Oct4 gene ablation. They show that Oct4 is dis- pensable for self-renewal in intestinal epithelium, bone marrow mesenchymal stem cells and HSC, hair follicle, brain and ... ng/ml stem cell factor (SCF), 10 ng/ml flt-3 li gand, 10 n g/ml thrombopoietin and 2 mM L-glutamine ( Stem Cell Technologies Inc, UK). Cells were plated at a density of ~2 × 10 5 c...

Ngày tải lên: 11/08/2014, 07:21

... past 2years and what the future of genomic medicine might hold. Transformational eect of systems medicine Since we discussed systems medicine as the future of medical genomics and healthcare ... of Public Health Genomics, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MS E61, Atlanta, GA 30333, USA. 4 Departments of Molecular and Human Genetics and Pedia...

Ngày tải lên: 11/08/2014, 12:21

... search and analysis of similar protein sequences. His two main points were that HMMER3 is now nearly as fast as BLAST, and that it can use ‘forward’ scores for sequence similarity and give ... venerable and a timely conference. Venerable because it boasts an almost 20 year history as a venue to report advances in bioinformatics - yet also timely as we head into the era of person...

Ngày tải lên: 11/08/2014, 12:20

Ngày tải lên: 20/02/2014, 18:20

... Uk and vk often co-occur, as do uk and uk+z. The direct association between uk and vk, and the direct association between uk and Uk+l give rise to an indirect association between v~ and uk+l. ... and let N be the total number of co-occuring word token pairs: K = ~(u,v) k(u,v/, N = ~(~,v) n(u,v). By definition, A = KIN. (4) Equating the right-hand sides of Equations (3)...

Ngày tải lên: 22/02/2014, 03:20

... experimental approach, the ligand of NKG2D, an activating receptor expressed on NK and T cells, was fused to anti-tumor IgG fragments to specif- ically coat this ligand on tumor cells and to induce their lysis ... is a good candidate for a tumor target, as it is a transmembrane tyrosine kinase receptor highly expressed on breast, ovary and lung car- cinomas [9,10], as well as in saliv...

Ngày tải lên: 23/03/2014, 06:20

... context (Adler and Elhadad, 2006; Shacham and Wintner, 2007; Bar-haim et al., 2008; Habash and Rambow, 2005), or jointly with parsing (Tsarfaty, 2006; Gold- berg and Tsarfaty, 2008; Green and Manning, ... Nivre, and Evelina Andersson. 2011. Evaluating dependency parsing: Robust and heuristics-free cross-framework evaluation. In Pro- ceedings of EMNLP. Reut Tsarfaty, Joakim Nivre...

Ngày tải lên: 23/03/2014, 14:20

... (P, ~-p) is a node in S and x, y E P and x N-p y, then x ">s Y. • If (P, ~-p) is a node in S and x, y E P and x ~-p y, then ifz is an element which occurs in S and y dominates z in S ... some element x occurs in R and x a, then a dominates x in T 3. If x and y occur in R and x dominates y in R then x dominates y in T 4. If x and y occur in S and x dominat...

Ngày tải lên: 23/03/2014, 19:20