báo cáo khoa học: " Future medical applications of single-cell sequencing in cancer" pot

... single-molecule sequencing, by requiring lower amounts of input DNA. In summary, the future medical applications of single- cell sequencing will be in early detection, monitoring CTCs during ... for sorting single cells into 96-well Figure 1. Medical applications of single-cell sequencing. (a) Proling of rare tumor cells in scarce clinical samples, such as n...

Ngày tải lên: 11/08/2014, 12:21

... dosing. Using this methodology, we examined the effects of methylglyoxal on an in vivo T. brucei infection. The maximum achiev- able methylglyoxal concentration in blood following oral dosing of ... for 72 h. Concentrations of inhib- itor causing a 50% reduction in growth (EC 50 ) were deter- mined using the following two-parameter equation by nonlinear regression using grafit: y...

Ngày tải lên: 23/03/2014, 06:20

... exploit this understanding of the dynamic system to obtain an interpretation of the biochemical nature of the activating and inhibiting modes. In essence, we do this by mapping the measured phase ... those of Fig. 7; the remaining values are C a 2 A tot ¼ 12.1mm 2 and C a 2 N tot ¼ 2.6mm 2 . With this in mind, we can use the on ⁄ off switching of PFK to rationalize the results...

Ngày tải lên: 30/03/2014, 16:20

... Are the main points in my essay clearly stated? d) Do the main points in my essay relate to my original thesis statement? If these questions are expressed in general terms, they are of little ... (1998) (see also Larkey and Croft (1996) for descriptions of additional applications) . In Larkey (1998), sets of essays used for training scoring models typically contain fewe...

Ngày tải lên: 31/03/2014, 04:20

... Some Novel Applications of Explanation-Based Learning to Parsing Lexicalized Tree-Adjoining Grammars" B. Srinivas and Aravind K. Joshi Department of Computer and Information Science ... to be in this general direction, it is distinct in that it ex- ploits some of the key properties of LTAG to (a) achieve an immediate generalization of parses in the training s...

Ngày tải lên: 20/02/2014, 22:20

... role in sustaining adherence to antiretroviral treatment (ART) for HIV infection [7]. The topic of adherence to ART has been widely studied since the beginning of the HIV epidemic [8]. In injecting ... OMT was defined as having reported use of opioids in a non- medical context, and/or the misuse of the prescribed oral OMT by an inappropriate route of administration (injec...

Ngày tải lên: 11/08/2014, 18:20

... proteinase K. DPP IV levels following stimulation with insulin and bpV(phen) In order to examine changes in DPP IV levels follow- ing insulin stimulation, rats were injected with the PTP inhibitor ... dynamic role of the translocons [54,55] and membrane restructuring enzymes [56] in protein targeting is beginning to be perceived. For instance, one striking example of c-Src location...

Ngày tải lên: 19/02/2014, 07:20

... current DA tagging as a work in progress. 4.3.3 Zone coding Each of the five main areas had a correspond- ing set of subzones. A subzone is a building, a room within a building, or any other ... corresponding se- ries of progressive moments in time portraying en- try into the Bank subzone as represented in RAT. In the annotation, each avatar name is recorded in or- der o...

Ngày tải lên: 20/02/2014, 04:20

... struc- tures giving rise to th e same set of dependen- cies (a piece of a tile of a roof of a house vs. a piece of a roof of a tile of a house) cannot be distinguished. We believe that an inverted index ... performance of 87.6% for a train- ing set of about 85% of WSJ. That num- ber is not that far from the 82.8% achieved by Collins’ parser in our experiments when traine...

Ngày tải lên: 20/02/2014, 12:20

... strings (we will come back to word strings in section 5). Each corpus was divided into 10 training/test set splits of 90%/10% (n-fold testing), and each training set was randomly divided into ... believe that our result is quite promising for the future of unsupervised parsing. In putting our best f-score in table 4 into perspective, it should be kept in mind that the gold...

Ngày tải lên: 20/02/2014, 12:20