báo cáo khoa học: "Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data" ppt

... accuracy in the indepe ndent dataset despite a median cumulative genetic risk in the discovery dataset of 0.90 for the case group, and 0.01 for the control group. For the validation dataset, the values ... case (P-Hat). The median of the cumulative genetic risk in the case group is 0.90, and in the control group 0.01. Quantiles of the estimated cumulat...

Ngày tải lên: 11/08/2014, 12:21

... function. This new form of Q o domain, with the common VLP(133–135) sequence, has therefore been used throughout the other studies reported here. The effect of other variations in the Q o binding ... inhibit bc 1 activity. These are either specific for the Q i site, such as antimycin, or for the Q o site, such as myxothiazol, stigmatellin, natural and synthetic strobilurins. So...

Ngày tải lên: 16/03/2014, 16:20

... categories in the training data. arguments (17.57%) are moved either from the left side of their predicates to the right side after transla- tion (accounting for 11.19%) or from the right side to the left ... semantically important, they also form a major part of the sentences. Therefore, whether verbal predicates are trans- lated correctly or not has a great impact on the...

Ngày tải lên: 19/02/2014, 19:20

... significance of the scores produced by our evaluation methods (for example, the limits of their ranges) before trying to interpret them. There are theoretical principles which indicate that the evaluation ... expected order on the other adjective. We normalize the result to the range 0 to 1 using a simple linear transformation. The second similarity module utilizes the...

Ngày tải lên: 08/03/2014, 07:20

... cells from the early blastomere stage to the blastocyst stage is accompanied by a change in the epigenetic profile that directs the differentiation pathway to either the embryo proper or the placenta. ... 1. Epigenetic distances between ES cells and other stem cells derived from developing embryos. ES cells derived from the inner cell mass (ICM) of blastocysts and EG cells...

Ngày tải lên: 23/03/2014, 07:20

... molecular interface in the case of the former helicase. Further- more, the absence of the S259 OH group in the mutated viral enzyme prevents the formation of one hydrogen bond with bananin, accounting for the reduced ... is very far from the active site suggests that S259 is located either in an allosteric site of the enzyme or in a critical position for the overall...

Ngày tải lên: 28/03/2014, 23:20

... finitive surgery, an d concluded that the pat tern, namely the probability and sites of lymph node metastasis from tumors originated from the head or the body/tail of the pancreas can be followed. In ... relatively rare (all less than 10%). Therefore, group 1-7 can be excluded from the high-dose coverage during precision radiation therapy. The metastatic rate to the hepa...

Ngày tải lên: 09/08/2014, 08:23

... within their historical, intel- lectual and political foundations. The dominant research themes from 1981 to 2008 are summarized in Figure 1 [adapted from [7,8]]. The early years 1981 - 1996 The ... purposes) defend the character of a society. It strikes at the mili- tary, and subverts the forces of order and peacekeeping." The US National Intelligence Council then prod...

Ngày tải lên: 11/08/2014, 14:21

... form the basis of alloca tions from the global social health protection fund, and for the accountability for the allocations received. On this point, the n ational strategies elaborated for the ... of the world should assist each other (or not) in realizing their full potential as human beings and as societies. The para- digm that has been adopted since the adoption...

Ngày tải lên: 11/08/2014, 14:21

... at either the level of the practice or the level of the individual. The theoretical models will be tested using standard multiple regression analysis and structural equation modelling. For predictor ... size together explained 31% of the variance in diabetes management. These authors, along with others [4,5], identified the need for a better understanding of the relation...

Ngày tải lên: 11/08/2014, 16:20