báo cáo khoa học: " Pharmacogenomic considerations in the opioid management of pain" pot
báo cáo khoa học: " Pharmacogenomic considerations in the opioid management of pain" pot
... renal epithelial cells and also on the
luminal side of endothelial cells in the blood-brain
barrier, and it is a major determinant of the pharmaco-
kinetics and pharmacodynamics of several opioids ... standard of
care for anesthesiologists and pain management physi-
cians. In the near future, pharmacogenomic approaches
in pain management could lead to individual...
Báo cáo khoa học: Conserved residues in the N-domain of the AAA+ chaperone ClpA regulate substrate recognition and unfolding pdf
... two
elements in ClpA, one in the N-domain and the other
in the pore of the ClpA hexamer. In the case of short
unstructured peptides or unfolded proteins such as
casein, binding to the tyrosine residues in ... three
domains: an N-domain and two ATP-binding domains
referred to as the D1 and D2 domains. Interestingly,
deletion of the N-domain from ClpA not only ab...
Báo cáo khoa học: "Some Problems in the Mechanical Translation of German" pdf
...
ent. These arise with verbs of perceiving and
certain others such as "permitting," when the
substantive which is the direct object of the
main verb is also the subject of the infinitive. ... the feminine singu-
lar dative.
2. The masculine singular accusative of wel-
cher is identical to the dative plural.
3. The nominative form is identical to the...
Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx
... construct in which the N-terminus of the
OTR is replaced with the corresponding sequence of
the V
1a
R [10]. The role of the N-terminus has been
addressed recently by alanine-scanning mutagenesis of the
N-terminus ... off-state. The unique ability of
arginyl to fulfil this constraining function in the N-terminus
of the V
1a
R is similar to the unique const...
Báo cáo khoa học: Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability pptx
... located in
the interface between monomers [18]. Assuming that the
catalytic sites of HDC are also in the interface between
monomers, we postulated the hypothesis that the observed
high degree of rotation ... locate the catalytic center and predict the shape of the
dimeric protein. The model reinforced our hypothesis
proposed above. To further address this hypothesi...
Báo cáo khoa học: Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations pot
... cataloging
the structure to class I. As the bulky NH
2
group on guanine was believed
to prevent binding of the drug in the minor groove, the detailed nature of
several of the amidinium and guanidinium ... sequence of the
decamer. Part of the spine of hydration is substituted
by the amide N atoms of the minor groove binder.
As the crystal engineering techn...
Báo cáo khoa học: "Recent advances in the surgical care of breast cancer patients" pps
... directing planes of sur-
gery during the exc ision. This in turn is helpful in guar-
anteeing both negative margins and an adequate
contour of resection in order to minimize the volume of
excision.
Identification ... 5
years at the multivariate analysis [237].
In the US this information has resulted in a rapid
increment of Breast Fellowship, recognizing that appro-
p...
Báo cáo khoa hoc:" Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma progression" potx
... con-
taining infiltrating lymphocytes and showing low Clark
level lesions. It is of note that we are unable to verify
whether the missingness of data on TILs in this study is
informative therefore these ... were combined into a single variable, the 'phe-
notypic index' [17]. This index, with minimum and max-
imum values of 1 and 5, represents the sum of points
assign...
Báo cáo khoa hoc:" Perfluorodecaline residue in the anterior chamber of a patient with an intact crystalline lens: a case report" ppt
... report.
Competing interests
The author(s) declare that they have no competing inter-
ests.
Colour images of perfluorodecalin residue in anterior cham-ber of a 17-year-old male with an intact crystalline ... images of perfluorodecalin residue in anterior cham-
ber of a 17-year-old male with an intact crystalline lens.
Colour images of the retina before and after operationFigu...
báo cáo khoa học: " Translational bioinformatics in the cloud: an affordable alternative" pot
... cloud computing allows
free configuration of virtual machin e instances, thereby
sharing the burden of security with the user. Second,
cloud computing requires the t ransfer of data, which
introduces ... operating the cluster, which was divided by the
number of CPUs in the cluster to estimate the per-
CPU/per-hour cost of operating the local cluster.
Results
From o...
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