báo cáo khoa học: " Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics" pps
báo cáo khoa học: " Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics" pps
... for the diagnosis, prognosis and management of RCC.© 2010 BioMed Central Ltd Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeuticsMark R Morris1,2 and Eamonn ... article as: Morris MR, Maher ER: Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics. Genome Medicine 2010, 2:59.Morris and Maher Genome Medicine 2010, 2:59 ... and their relationship to pathways of tumor development. Increased understanding of RCC epigenetics provides new insights into the molecular pathogenesis of RCC and opportunities for developing...
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Báo cáo khoa học: Training of yeast cell dynamics ppt
... increase of the rate of the trans-porter and according to the positive control of the transporter on the frequency [4] this should increase the eigenfrequency of the system and thereby move the eigenfrequency ... of inhibition of protein synthesis on the amplitude of the intracellular NADH oscillation. The amplitude of the intracellularNADH oscillation was determined in the presence of 0 (d), 5 (–) and ... oscillations was close to the eigenfrequency of the cells, than at other frequencies (the eigenfrequency of the cells was taken to be the frequency of the autonomous oscillations they engagedin under...
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Báo cáo khoa học: "Thickness of cumulus cell layer is a significant factor in meiotic competence of buffalo oocytes" potx
... 85, 54, and 26% forgrade 1 (≥= 5 layers of cumulus cells and homogenouscytoplasm), grade 2 (≤= 4 layers of cumulus cells and homogenous cytoplasm) and grade 3 (without cumulus cells and irregular ... the cool months of winter and season of experiment be reported in publications. Ourunderstanding is that the studies on abattoir ovaries may notbe truly representative of the potential of the ... findings of 1.49 [8] and 1.76 [27] for the same breed of buffalo. This difference in oocyte yield isdue to seasonal variation because the other studies wereconducted during the cooler months of winter....
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Báo cáo khoa học: "Glycogen-rich clear cell carcinoma of the breast" pps
... seen. There wasClear -cell carcinoma of the breast, resembling clear -cell car-cinoma of the kidneyFigure 2Clear -cell carcinoma of the breast, resembling clear -cell car-cinoma of the kidney. The ... the large size of the primary tumour. The prognosis of glycogen-rich clear cell carcinoma of the breast is reported to be not particularly favorable and maybe similar to or worse than that of ... throughout the body. The vac-uolated cytoplasm in many of these tumors can be attrib-uted to large quantities of glycogen, as in clear cell carcinomas of the vagina, cervix, endometrium, ovary and salivary...
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Báo cáo khoa học: "Conservatively treated glassy cell carcinoma of the cervix" pot
... conceived of the study, participated in its design and drafting. VS participated in the design of the study and collected the clinical data. MP participated in the design of the study and collected the ... carried out the histopathological evaluation. GS conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final ... updated series of 72 cases and review of the literature.Gynecol Oncol 2004, 94:614-623.12. Gray HJ, Garcia R, Tamimi HK, Koh WJ, Goff BA, Greer BE, Paley PJ:Glassy cell carcinoma of the cervix...
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Báo cáo khoa học: " Role of p53 mutation in the effect of boron neutron capture therapy on oral squamous cell carcinoma" ppsx
... provided cell lines and participated in the design of the study. TO provided cell lines and partic-ipated in the design of the study. YY conceived of the study and participated in its design and ... were 8 and 36%, respectively (Figure 1).Suppression of the proliferation of oral SCC cells by BNCTTo determine the effect of BNCT on the proliferation of cells, SAS/neo and SAS/mp53 cells were ... cells irrespective of the p53 status should be clarified.In the present study, we examined the effects of BNCT on the proliferation, cell cycle, and cell cycle-related proteins of oral SCC cells...
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báo cáo khoa học: "Types of red cell potassium in seven of cattle Spanish native breeds" pdf
... SENGUPTA, 1974) and yaks (KAMENEK, 1977). The purpose of the present paper is to describe the existence of polymorphism of the erythrocyte potassium in six of the seven Spanish ... (127) and Asturiana de la Montana (106). The sampling of each breed was carried out at randomfrom private farmers. The majority of the animals studied were cows. The blood ... the small number of HK animals found generally in that species. We hope to collect asufficiently large number of animals among the offspring of parents with known cell type...
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báo cáo khoa học: "Evolution of T-cell clonality in a patient with Ph-negative acute lymphocytic leukemia occurring after interferon and imatinib therapy for Ph-positive chronic myeloid leukemia" pot
... differ-ence in the expressional number of TCR Va/Vbbetween the disease stage of CP and that of Ph-nega-tive ALL. Only 9 of all 29 Va and 4 of all 24 Vb subfa-milies could be detected at the time of CP, ... al and our previousstudies [16,23,24]. Aliquots of the cDNA (1 μl) wereamplified in 25 μl reactions with one of the 29 Va pri-mers and a Ca primer or one of 24 Vb primers and aCb primer. The ... be interesting to detect the evolution of T -cell clonality in the patient at different disease status. The features of restric tive usage and absence of par-tial T cell clones could be found...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... normally in oleate-treated cells; and (e) the presence of relatively low amounts of oleate protected cells from stearate-induced toxicity and restored the ability of the cells to accumulate triacylglycerols. ... 5B). The ER is the site of synthesis of all secretory pro-teins and resident proteins of the membrane system, and any perturbation that compromises the protein-folding capacity of the organelle ... activation of stearate in the form of stearoyl-CoA was a necessary step for the lipotoxiceffect; (d) the capacity of cells to produce and accumulate triacylglycerols in the form of lipid droplets...
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Tài liệu Báo cáo khoa học: Degradation of tropoelastin by matrix metalloproteinases – cleavage site specificities and release of matrikines pptx
... residues 96–103) of the crystallized proform of MMP-9 (1lj6.pdb) and the coordinates of the peptideIAG cocrystallized with MMP-12 (2oxw.pdb) as template.As the prodomain of MMP-9 and the bound peptide ... metallopro-teinases MMP-7, MMP-9, and MMP-12 and to compare the cleavage sitespecificities of the enzymes using complementary MS techniques and molec-ular modeling. Furthermore, the ability of the three proteases ... MMP-9(Val398) and MMP-7 (Ala215), and Glu219 of MMP-7 and MMP-12 is mutated to Gln402 in MMP-9. The model of the bound substrate with Lys at P1¢ (Fig. 3C)indicates the neighborhood of the polar...
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