báo cáo khoa học: " Shared pathways to infectious disease susceptibility?" ppt

... studies of immune response defects and infec- tious disease outcomes strongly suggested that infectious diseases would have shared pathways to disease. Severe combined immune deficiency (SCID) ... innate detection mechanisms may not be as shared among diseases as immune response mechanisms. © 2010 BioMed Central Ltd Shared pathways to infectious disease susceptibili...

Ngày tải lên: 11/08/2014, 12:20

... receptor ETR1 cause enhanced sensitivity and exaggerated response to ethylene in Arabidopsis. Plant Physiol 2002, 129:1557-1567. 36. Tosti N, Pasqualini S, Borgogni A, Ederli L, Falistocco ... AtGSTU24 has previously been shown to be sharply and rapidly induced by the herbicides ace- tochlor and metolachlor, as well as the explosives 2,4,6- trinitrotoluene and hexahydro-1,3,5-trinitro-1,...

Ngày tải lên: 12/08/2014, 03:21

... these pathways may converge to influence protein folding, protein stability and ultimately mitochondrial function which appear to be central to the mechanism of neuronal cell death in PD. Autosomal ... DJ-1 in mitochondrial function, the fact that Drosophila lacking DJ-1 exhibit increased sensitivity to environmental mitochondrial toxins [44,51] does point to a role for DJ-1 in mit...

Ngày tải lên: 18/02/2014, 14:20

... bodies [17–19]. Pantothenate kinase is an essential regulatory enzyme in co-enzyme A biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine ... disease) may be misleading attempts to find common pathways to pathogenesis. Rather, we suggest, grouping the different loci which lead to different Lewy body disease may be more revealing...

Ngày tải lên: 18/02/2014, 14:20

... considered to be a key factor in the growth and survival of chondrocytes. Hypoxia is known to regulate the expression of many genes, but little is known about its role in either apoptosis or anti-apoptosis, ... HCT116 cells to proteasome inhibitors. Int J Oncol 24, 935–941. 19 Falchuk KH, Goetzl EJ & Kulka JP (1970) Respiratory gases of synovial fluids. An approach to synovial tiss...

Ngày tải lên: 18/02/2014, 14:20

... binding to this crystallin by ITC and determined the binding constant for the calcium mimic probe. Terbium is believed to bind strongly to calcium-binding sites of proteins compared to calcium due to ... these contradictory observations, it is important to investigate whether b-crystallins from vertebrate lenses bind calcium or not. In this context, to establish calcium-binding...

Ngày tải lên: 18/02/2014, 16:20

... common to organic synthesis but not yet amenable to protein modification. As new methodologies emerge, the study of other PTMs and that of regulatory PTMs will hope- fully provide a powerful tool ... degree of branching cooperate to regulate cell proliferation and differentia- tion. Cell 129, 123–134. 16 Comstock LE & Kasper DL (2006) Bacterial glycans: key mediators of diverse host...

Ngày tải lên: 18/02/2014, 17:20

... storage compartments for a number of pro-death proteins, such as cytochrome c, which are released into the cytoplasm as a consequence of apoptotic signals. The release of these apoptotic factors ... 2006 FEBS corresponding to Bid-a6, which has been shown previ- ously to be able to release calcein from PtdCho LUVs [28], assayed at L ⁄ P molar ratios up to % 5, was unable to induce th...

Ngày tải lên: 19/02/2014, 07:20

... receptor’s primary sequence shows stri- king similarities to the somatostatin receptor family, most notably in the transmembrane domains. The pharmacological relatedness of somatostatin receptors is ... laboratory from rats show only diffuse URP mRNA expression in certain areas of the medulla oblongata that are not known to project to the PPT. There will be a need to produce selectiv...

Ngày tải lên: 19/02/2014, 07:20

... difficult to purify and has a complex double hydrophobic core (Fig. 4). The authors first sought to directly randomize the structural residues in TIM to estimate the overall tolerance to mutation. ... sequence resemblance to each other or to proteins known in nature [69]. However, these proteins were not sufficiently soluble to be examined in vitro except as fusions to maltose bi...

Ngày tải lên: 19/02/2014, 12:20