báo cáo khoa học: " Translational bioinformatics in the cloud: an affordable alternative" pot

... enabled by translational bioinformatics and cloud computing, that empo wers clinician scientists to make full use of the available molecular data for formulating and evaluating important translational ... Butte AJ: Translational bioinformatics applications in genome medicine. Genome Med 2009, 1:64. 3. Kann MG: Advances in translational bioinformatics: computational approach...

Ngày tải lên: 11/08/2014, 12:20

... function of the information gained by giving a joint descrip- tion of a and b in terms of what they have in com- mon, compared to describing a and b separately. The relevant data in the lexical domain ... human), they had distinct types (e.g. duke, prince, bachelor). In the other half, entities were of the same type, that is the NPs introducing them had the same nominal...

Ngày tải lên: 17/03/2014, 04:20

... consistency and com- pactness in the bilingual lexicon, and therefore in the transfer module, are achieved. The next steps will include the implementation of the mechanism to drive the bilingual ... lexical rules, the refining and testing of the semantic classification, the isolation of further regularities and the investigation of other types of PP's. Ackno...

Ngày tải lên: 23/03/2014, 20:20

... into the standard of care for anesthesiologists and pain management physi- cians. In the near future, pharmacogenomic approaches in pain management could lead to individualized therapy to ... multidrug resistance 1 (MDRD1) [5]. It is expressed in hepatic, intestinal and renal epithelial cells and also on the luminal side of endothelial cells in the blood-brain barrier, a...

Ngày tải lên: 11/08/2014, 12:20

... reorganization of the follicular epithelium in the resulting adults [40]. DmE75A and DmE75B have been implicated in defining the transition stages 8 and 9 of the egg chambers through either inducing or ... Moses, and the balance between these two proteins determines Drosophila growth rate [76]. In A. aegypti, the maximum AaHR78 transcript abundance in the fat body coin- c...

Ngày tải lên: 18/02/2014, 13:20

... molecule inhibitors, but the potential of using peptides as the starting point in the generation of therapeutics is now a growing area [18,19]. Peptides harbour the potential for chemical and biological ... were synthesized for analysis, extending the number of interactions from 10 to 45, permitting a rigid interpretation in distinguish- ing interacting from noninteracting prote...

Ngày tải lên: 18/02/2014, 13:20

... expect them also to be expressed in a nicotine- dependent manner. In order to investigate this, we analyzed the transcription of these genes in the pres- ence and absence of nicotine in the growth ... [ 14 C]Nicotine metabolites in the medium of A. nicotinovo- rans pAO1 and growth of A. nicotinovorans pAO1 and A. nicotino- vorans lacking pAO1 on CH 3 -4-aminobutyrate, 4-amin...

Ngày tải lên: 19/02/2014, 07:20

... genome organization at the sequence level. Delineating compositionally homogeneous G + C domains in DNA sequences can provide much insight into the understanding of the organization and biological ... shown in Fig. 2, the domains obtained can delineate the variations of the cumulative GC profile and the density distribution of CpG islands more and more accurately with decreas...

Ngày tải lên: 19/02/2014, 07:20

... balance between these antioxidant enzymes is rele- vant for cell and neuronal functions [8,18]. The fact that an increase in catalase activity may not result in neurotoxic effects during SE indicates ... quantities of oxidizable lipids and metals, and, moreover, has fewer antioxidant mechanisms than other tissues [8]. Free radicals are chemical entities characterized by an orbital c...

Ngày tải lên: 19/02/2014, 16:20

... unusual in having two histidine residues (rather than the His-Asn pair seen in OYE, MR and some of the other member proteins; Fig. 1B) in the active site for ligand and substrate binding. For ... His181 and His184 are important in the binding of coenzyme, steroids, nitro- aromatic ligands and the substrate 2-cyclohexen-1-one. The H181A and H184A enzymes retain activity in...

Ngày tải lên: 20/02/2014, 02:21