báo cáo khoa học: " The public health utility of genome-wide association study results for smoking behavior" docx

... testing of smoking will result in public health improvements [18] and reduce the likelihood of harm; such harm could include a lowering of the motivation to quit or of the self-efficacy for quitting, ... multiple risk variants and their interactions also may yield stronger associations for different smoking behaviors. Clinical validity of GWAS findings for smoki...

Ngày tải lên: 11/08/2014, 12:20

... to public health the world over. Global health governance strategies need to address the erosion of antimicrobial effectiveness on three levels. Firstly, mechanisms to provide incentives for the ... 1 of 2 (page number not for citation purposes) Globalization and Health Open Access Editorial The global health governance of antimicrobial effectiveness Greg Martin* A...

Ngày tải lên: 11/08/2014, 18:20

... that. The practical side of e- health solutions is missing from the toolkit. Some of the questions leave a lot of room for interpretation and there are many questions in one question and then ... range of professionals for a range of different e -health systems. Users have to accept the need to do a bit of local adaptation and thinking about how best to use the...

Ngày tải lên: 10/08/2014, 11:20

... retained 60% of the initial activity at 45 °C for 90 min when assayed at 35 °C (Fig. 3A,B). The presence of Ca 2+ increased the thermal stability of PhyH and PhyH-DII. After incubation at 60 °C for 30 ... We focus on the function and relationship of the two single domains. Additionally, the possibility that fusion of the PhyH N-terminal domain to other single-doma...

Ngày tải lên: 14/02/2014, 15:20

... oxidation. By contrast, the results of the present study show that A n B n GAPDH isoforms, representing the major isoforms of photosynthetic GAPDH in chloroplasts of higher plants, though being ... [20]. On the other hand, the activity of the purified recombinant C153S mutant was similar to that of the wild-type protein (data not shown), and the kinetics of inac...

Ngày tải lên: 19/02/2014, 05:20

... position as that of the Sm-like SmAP3 of the archaea P. aerophilum [31] and, as in the case of SmAP3, the possibility of two conformations for the C-terminal domain could not be excluded. The multiple ... another. The difference between the Hfqs results from the insertion of a fragment of variable length between the first 67 amino acids and the end of t...

Ngày tải lên: 19/02/2014, 12:20

... performance is influenced by the frequency of graphemic units in the language and by the predictability of their mapping to phonemes. We argue that these results implicate the availability of ... conversion. These findings are incompatible with current implementations of the dual-route theory (Coltheart et aL, 1993). The "central dogma" of this theor...

Ngày tải lên: 20/02/2014, 19:20

... member of the d-subdivision) were unsuccessful or led to the degradation of the isolated species [10]; as a consequence, the stoichiometry of the complex was not established. The formation of stable NrfHA ... containing the double of NrfA subunit in respect to the NrfH subunit. Nevertheless, inside these huge aggregates there are species of the type a 2 b 2. The...

Ngày tải lên: 21/02/2014, 00:20

... class="bi x0 y0 w1 h 1" alt ="" "point of view" for a problem solver at each point in the problem solving from a record of the problem solving report and a record of moves made. Then, ... model of the role of point of view in problem solving. SUMMARY We have reported here a three pronged approach to the study of problem solving action and report:...

Ngày tải lên: 21/02/2014, 20:20

... test whether the removal of the second half of the PolC N-terminus would help to improve the results further. Therefore, we took only the fragment of the multiple sequence alignment covering the ... did. After the iterative mod- eling procedure, the assessment results for the best B. subtilis PolC-NI model were slightly worse than for the PolC-NII domain, y...

Ngày tải lên: 05/03/2014, 23:20