báo cáo khoa học: " Locus Reference Genomic sequences: an improved basis for describing human DNA variants" pdf

... 29:777-807. doi:10.1186/gm145 Cite this article as: Dalgleish R, et al.: Locus Reference Genomic sequences: an improved basis for describing human DNA variants. Genome Medicine 2010, 2:24. Dalgleish et al. Genome ... the LRG web site (http://www.lrg-sequence.org). Locus Reference Genomic sequences: an improved basis for describing human DNA varian...

Ngày tải lên: 11/08/2014, 12:20

... grants from the Slovak Grant Agency (1 ⁄ 1274 ⁄ 04 and 1 ⁄ 3254 ⁄ 06) and the Science and Technology Assistance Agency (APVT- 20-006604). I would like to thank Gavin Cowper and Lenka Sieber for ... November 2008) doi:10.1111/j.1742-4658.2008.06782.x Naturally occurring G-rich DNA sequences that are able to form G-quad- ruplex structures appear as potential targets for anti-cancer chemot...

Ngày tải lên: 23/03/2014, 06:20

... thank Mauricio Bonifacino and Daniel Austin for assist- ance in obtaining plant material for the study, Tony Omeis for greenhouse assistance, Tim Chumley for technical support, Robert Jansen for ... plants, produced and screened the par- tial genomic fosmid libraries, annotated and analyzed the plastid genomes, and drafted the manuscript. JVK sub- cloned, sequenced, and assembled...

Ngày tải lên: 12/08/2014, 05:20

... Mock B Anti-Cβ2 Merge Merge Anti-γ-tubulin Anti-Cβ2 Anti-γ-tubulin Transfection Cβ2 Mock C Fig. 2. The human Cb2 cDNA encodes an active protein kinase and the Cb2 peptide antibody is specific for human Cb2. (A) Human 293T cells were transiently ... immunofluorescence of human T cells using anti-Cb2(SNO103) in combination with anti-RIa and anti-RIIa. Human T cells were incubated wi...

Ngày tải lên: 16/03/2014, 18:20

... the Netherlands. This work was supported by grants Ha 2372/1-3 and Ha 2372/3-2 from the Deutsche Forschungsgemeinschaft, and by a grant from the Alexander von Hum boldt Foundation (a maintenance grant to ... to increased viral pathogenicity in humans (Keshan disease) and in animal experiments [44]. One obvious function of selenium relates to its role as an antioxidant as a constituent part...

Ngày tải lên: 30/03/2014, 15:20

... Beaulieu S: Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the man- agement of patients with bipolar disorder: update 2007. Bipo- lar Disord 2006, 8(6):721-739. 38. Frances ... disorder. Against acute mania, SGAs might act faster and better than lithium and anticonvulsants while their efficacy during the maintenance phase may be comparable. Quetiapine and the ola...

Ngày tải lên: 08/08/2014, 23:20

... with different units and scales cannot be aggregated before being transformed to a common scale (normalization). Of the many existing choices for normalization, ranking and assignment to a categorical scale ... subjective choices and chance variation in the underlying data on provider performance can be modelled in higher order Monte Carlo experiments. The importance of uncertainty analysis...

Ngày tải lên: 11/08/2014, 16:20

... 2011 Published: 29 March 2011 References 1. Cella D: The Functional Assessment of Cancer Therapy-Anemia (FACT- An) Scale: A new tool for the assessment of outcomes in cancer anemia and fatigue. Semin Hemtol ... was translated to Danish, French, German, and Spanish. A total of 52 patients at five centres (in Austria, Denmark, France, Spain, and the UK) completed the 4 4 items and commented...

Ngày tải lên: 12/08/2014, 01:22

... develop a reference Identlfzcatmn and plan recognition mechanism that can exhibit more " ;human- hke ' tolerance of such utterances. Our goal zs to build a more robust system that can handle ... 4842, Bolt Beranek and Newman Inc. Also Consul Note # 5, USC/Information Sciences Institute. October 1981. [17] L4tman, Diane J. and James F. Allen. A Plan Recogmtion Model for Cl...

Ngày tải lên: 21/02/2014, 20:20

... im- portant to note that FHMM outperforms the cas- caded HMM in terms of NP accuracy for all but one model. For instance, FHMM-CT achieves an NP accuracy of 95.93%, significantly higher than both the ... labeling. Acknowledgments The author would like to thank Katrin Kirchhoff, Jeff Bilmes, and Gang Ji for insightful discussions, Chris Bartels for support on GMTK, and the two anonymo...

Ngày tải lên: 08/03/2014, 04:22