báo cáo khoa học: " High-throughput analysis of chromosome translocations and other genome rearrangements in epithelial cancers" pdf

... Edwards PAW: High-throughput analysis of chromosome translocations and other genome rearrangements in epithelial cancers. Genome Medicine 2010, 2:19. Newman and Edwards Genome Medicine 2010, 2:19 ... found in common cancers, such as breast carcinoma, and some of these will prove to be important in cancer diagnosis and treatment. © 2010 BioMed Central Lt...

Ngày tải lên: 11/08/2014, 12:20

... concluded from the structural model of the PTS1-binding C-terminal domain of HpPex5p (Fig. 4). In this domain three of the seven Trp residues of HpPex5p are found. However, of these three residues only ... (amplitudes, correlation times and standard errors) are given in Table 1. Fig. 4. Model of the C terminal domain of HpPex5p. Molecular model of the TPR domain of HpP...

Ngày tải lên: 21/02/2014, 00:20

... value. The docking of MeMan into the carbohydrate-binding sites of Orysata and other JRLs was performed with the program insightii. The lowest apparent binding energy (E bind expressed in kcalÆmol )1 ) ... removed in a solu- tion of Tris-buffered saline containing 0.05% Tween 20 and washed by gently dipping the slides four times in successive washes of Tris-buffered saline...

Ngày tải lên: 14/03/2014, 23:20

... Constantinos E. Vorgias 3 and Pedro L. Mateo 1 1 Department of Physical Chemistry, Faculty of Sciences and Institute of Biotechnology, University of Granada, Spain; 2 Institute of Protein Research, ... Thermodynamics of structural stability and cooperative folding behaviour in proteins. Adv. Protein Chem. 43, 313–361. 35. Zhou, H X. (2002) Toward the physical basis of th...

Ngày tải lên: 23/03/2014, 12:20

... sub- strate acetyl-S-Ppant-PCP. Interestingly, after 5–10 min of incubation at 37 °C, no further hydrolysis of the remain- ing substrate was observed, indicating clear instability of this enzyme under the ... the removal of short acyl chains originating from aberrant decarboxylation of chain extender units from the thiol moiety of the 4¢-Ppant cofactors of acyl carrier proteins...

Ngày tải lên: 30/03/2014, 13:20

... file 15) in a PCR consisting of 1 min pre- incubation at 95°C and 30 cycles at 95°C for 30 s, 54°C for 30 s and 72°C for 2 min 30 s, followed by 1 cycle at 72°C for 5 min. Protein domains in th ... Alignment of the amino acid sequence of the Micrasterias denticulata expansin-resembling proteins Alignment of the amino acid sequence of the M. denticulata expansin-resembling pr...

Ngày tải lên: 11/08/2014, 11:21

... lentogenic, and asymptomatic enteric strains on the basis of their patho- genesis and virulence. The velogenic strains cause acute fatal infection of chickens of all age groups with clinical findings of ... dur- ing migration and the sharing of common wintering and breeding areas may provide opportunity for virus spread within and between countries and may help perpetuat...

Ngày tải lên: 12/08/2014, 04:20

... DISTRIBUTION OF NON-PRONOMINAL AND PRONOMINAL NOUN PHRASES Non-pronominal noun phrases play a role in indicating and realizing topic shifts in a dialogue. Since new subdialogues are ... pronominal noun phrases will tend to occur more frequently at the beginning of subdialogues than later in the subdialogues. On the other hand, pronominal noun phrases play a role in indic...

Ngày tải lên: 21/02/2014, 20:20

... both rule and N-gram based features. • Quantity of training data. • Modality (text or speech) of training data. We randomly divided the training corpus into ten equal pieces, and trained on subsets ... which sets of semantic atoms are consistent. The decoding pro- cess proceeds as follows: 3.1 Training and decoding Training data for ALTERF is supplied in the form of a text f...

Ngày tải lên: 08/03/2014, 21:20

... contaminat- ing protein that is either an accessory protein or a minor recombinant protein [34]. Studies show that an R88A mutation (arginine to alanine) in the nucleotide- binding site eliminates ... four) and inter-quadruplex binding sites in c-Myb and hTERT represents oppor- tunities for specific binding interactions. Some of these drug–G-quadruplex interactions have been addresse...

Ngày tải lên: 23/03/2014, 03:20