báo cáo khoa học: " Musings on genome medicine: Hepatitis C David G Nathan and Stuart H Orkin" ppsx

... the treatment of chronic hepatitis C in blacks and non-Hispanic whites. NEngl J Med 2004, 350:2265-2271. 2. NIH Consensus Statement on Management of Hepatitis C: 2002. NIH Consens State Sci ... Qi Y, Ge D, O’Huigin C, Kidd J, Kidd K, Khakoo SI, Alexander G, Goedert JJ, Kirk GD, Doneld SM, Rosen HR, Tobler LH, Busch MP, McHutchison JG, Goldstein DB, Carrington M: Genetic var...

Ngày tải lên: 11/08/2014, 12:20

... (along with physicians) by consumer-directed advertising campaigns operated by pharmaceutical companies, physician groups and hospitals. Only a concerted and successful effort to educate physicians, ... from the current mess? Cost control can only be achieved by behavioral changes. President Obama is a great educator. We have to pray that he can teach this course successfully. The...

Ngày tải lên: 11/08/2014, 12:20

... regarding the etiology of both CD and UC is that they are the result of very Musings Musings on genome medicine: Crohn’s disease David G Nathan and Stuart H Orkin Address: Dana-Farber Cancer Institute, ... all thought to be psychosomatic illnesses. The data supporting that argument were very thin at the time and the discovery of Helicobacter pylori as the cause of p...

Ngày tải lên: 11/08/2014, 12:20

... alpha-galactosidase-A (GLA) that lead to the accumulation of neutral glycosphingolipids, particularly globotriaosylceramid and galactosylceramid, both of which accumulate in the cornea and vasculature and cause ... enormous challenge to any healthcare budget and can only be intelligently supported in a highly productive and efficient health system. In the rare types of Gaucher...

Ngày tải lên: 11/08/2014, 12:20

... cofactor binding (Fig. 4C) and vice versa (Fig. 2). Thus, the large conformational change observed at the active site on substrate binding changes the position and orientation (relative to the ... catalytic activation Table 1. Comparison of distances (A ˚ ) of the superposition of the crystal structure of ligand-free dimeric rPAH (PDB id code 1PHZ), which contains both the regulatory a...

Ngày tải lên: 17/03/2014, 09:20

... c; IAP-2; a-fetoprotein. Apoptotic cell death is characterized by biochemical and morphological changes, which are largely caused by caspase activity. A class of cysteine proteases, known as caspases, which are constitutively ... developed by enhanced chemiluminescence staining using ECL reagents (Amersham Pharmacia Biotech). Gel calibration was per- formed with the Low Molecular Weight Ca...

Ngày tải lên: 08/03/2014, 08:20

... fre- High magnification view of lesion resected from the pancreas (haematoxylin and eosin)Figure 4 High magnification view of lesion resected from the pancreas (haematoxylin and eosin). High magnification ... magnification view of lesion resected from the pancreas (immunohistochemical staining with TTF-1)Figure 5 High magnification view of lesion resected from the pancreas (immunohistoc...

Ngày tải lên: 09/08/2014, 07:22

... Engl J Med 1981, 304:989-994. 3. Franchini M, Capra F, Tagliarferri A, Rossetti G, De Gioroncoli M, Rocca P, Aprili G, Gandini G: Update on Chronic hepatitis C in Hemophiliacs. Haematologica ... have consistently given congruent results for HCV genotyping using different genomic regions [8]. In this study, incongruent results were found for one HCV strain circulating in a hemophiliac...

Ngày tải lên: 12/08/2014, 04:20

... Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas B, Barry CE 3rd et al. (1998) Deciphering the biology of Mycobac- terium tuberculosis from the complete genome ... indicating a minor conformational change followed by the exposure of certain buried hydrophobic patches. CD and fluorescence data clearly suggested struc- tural variations among seven WhiB pro...

Ngày tải lên: 18/02/2014, 12:20

... show how Support Vector Machines along with kernel functions can ef- fectively represent syntax and semantics. Our experiments on question/answer classification show that the above models highly ... Infor- mation Retrieval has always been an interest- ing and challenging research area. Despite the high expectations, most of the results indicate that successfully using NLP is very complex...

Ngày tải lên: 20/02/2014, 09:20