báo cáo khoa học: " Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor d from Peroxisome proliferatoractivated receptor g in the ob/ob mouse" ppt

... skeletal muscle the concentrations of adenine were decreased and those of adenosines and ribose sugars from the adenosines were increased. Therefore, the decrease in amino acids may relate to increased oxidative ... ((dd)) Bar graph demonstrating the difference in the average integrated area of the serine peak from control and PPARd agonist treated liver. Error...

Ngày tải lên: 11/08/2014, 12:20

... Scores and X-loading Weights and Y-loa- dings in PLS regression shown in Fig. 5. Figure S4. Residual variance of calibrated X and of validated Y (NADPH) in PLS regression shown in Fig. 5. Figure ... the genes gndA, gsdA and tktA To be able to manipulate the genes gndA, gsdA and tktA encoding 6PGDH, G6 PDH and TKT, respect- ively, these genes were cloned by screening an A. nig...

Ngày tải lên: 07/03/2014, 17:20

... considered to be inappropriate, since TAE may cause hepatic infarction because of an a lready occluded portal vein. Under US and digital subtraction angiography (DSA) guidance (Figure 1b), the ... contributions HT reviewed relevant literature and drafted the manuscript. All authors provided clinical expertise and participated in drafting the manuscript. And all authors read and ap...

Ngày tải lên: 10/08/2014, 23:20

... for death increased with the NRBC concentration and seems to decline again when the NRBCs have disappeared from the circulation. The prognostic significance of NRBCs was independent of other ... concentration of NRBCs in the blood, but the prognosis improved when the NRBC concentration decreased. In particular, after the first detection of NRBCs in blood and...

Ngày tải lên: 13/08/2014, 03:21

... that invertase activity is increased during cold exposure in Rsch, whereas acitivity is reduced in C24 after 7 days in the cold. Regarding the question of Systems biology of cold acclimation in ... showed significantly higher activities of vInv at 0, 1 and 3 days of cold exposure. The activity of vInv in Rsch increased continuously during cold exposure, and became...

Ngày tải lên: 14/02/2014, 22:20

... and play a role in Tourette’s syndrome, nicotine addiction and Parkinson’s disease. Thus, nAChRs modulating the dopamine release gain increasing interest as drug targets, and identification of the ... subunits). c Unless otherwise indicated, K i values for inhibition of epibatidine binding are shown; B, inhibition of a-BTX binding. d Indicates cases where K d values were obtain...

Ngày tải lên: 19/02/2014, 12:20

... conforma- tional integrity. During protein unfolding ⁄ refolding, the addition of 2.5 protons (both E75 and E129 are the targets of protonation) results in SNase unfolding, with refolding at an early stage ... refolding [21]. Since then, many scientists have been interested in demonstrating this concept by using N-terminal and C-terminal fragments of SNase as models for the st...

Ngày tải lên: 20/02/2014, 01:20

... for the protein undergoing either aggregation or native folding. Analysis of the modulation of aggregation in bacte- ria was also of support in clarifying critical steps of oxidative folding of ... on formed aggregates triggering the degradation of mis- folded proteins while ClpB releases them from inclu- sion bodies (IBs) and presents unfolded polypeptides to the...

Ngày tải lên: 06/03/2014, 00:20

... tissue retains the ability to generate new adipocytes throughout life. Increased adipocyte number during aging has been implicated in the rising incidence and severity of obesity among the elderly ... of increased prolifera- tion or recruitment of preadipocytes [12], suggesting that these cyclin-dependent kinase inhibitors are important in the regulation of adipocyte n...

Ngày tải lên: 06/03/2014, 01:20

... 5¢-CCC TGA AGC CAG GAT GAG CCG CAG GGA AAG-3¢ and 5¢-TGG AGC TC G CTG ATT GGC CAG AAG CTG CAA- 3¢) was used for the following EMSA assay. The DNAÆpro- tein binding reaction was conducted in a mixture ... 5¢-TCT TGG ACA CGG TAG CAG AG-3¢; Ppp2r5c, forward, 5¢-AGT ACC TGG GGA TTG GC-3¢; Ppp2r5c, reverse, 5¢-CAT GGC TTG ATA TAC AAC GC-3¢; Gapdh, forward, 5¢-GGG CAC TTA CGG GTG TTA GA-3¢;...

Ngày tải lên: 06/03/2014, 02:20