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báo cáo khoa học: " Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor d from Peroxisome proliferatoractivated receptor g in the ob/ob mouse" ppt

báo cáo khoa học:

báo cáo khoa học: " Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor d from Peroxisome proliferatoractivated receptor g in the ob/ob mouse" ppt

... skeletalmuscle the concentrations of adenine were decreased andthose of adenosines and ribose sugars from the adenosineswere increased. Therefore, the decrease in amino acids mayrelate to increased oxidative ... ((dd))Bar graph demonstrating the difference in the average integrated area of the serinepeak from control and PPARd agonist treated liver. Error bars show standard error deviations from the ... coordinated the animal study and sample collection. JNH participated in intellectual discussion of the data. AWN participated in the design of the study, in intellectual discussion and held asupervisory...
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Báo cáo khoa học: Increased NADPH concentration obtained by metabolic engineering of the pentose phosphate pathway in Aspergillus niger docx

Báo cáo khoa học: Increased NADPH concentration obtained by metabolic engineering of the pentose phosphate pathway in Aspergillus niger docx

... Scores and X-loading Weights and Y-loa-dings in PLS regression shown in Fig. 5.Figure S4. Residual variance of calibrated X and of validated Y (NADPH) in PLS regression shown in Fig. 5.Figure ... the genes gndA, gsdA and tktATo be able to manipulate the genes gndA, gsdA andtktA encoding 6PGDH, G6 PDH and TKT, respect-ively, these genes were cloned by screening an A. nigerN400 genomic ... Overexpressing strains were obtained bycotransformation of the uridine requiring strain [39] NW129(cspA1 goxC17 pyrA6) with 1 lg of the plasmid pGW635containing the pyrA gene and 20 lg of a plasmid...
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báo cáo khoa học:

báo cáo khoa học: "Ultrasound-guided thrombin injection for the treatment of an iatrogenic hepatic artery pseudoaneurysm: a case report" ppt

... considered to be inappropriate, since TAE may cause hepatic infarction because of an a lready occluded portalvein. Under US and digital subtraction angiography(DSA) guidance (Figure 1b), the ... contributionsHT reviewed relevant literature and drafted the manuscript. All authorsprovided clinical expertise and participated in drafting the manuscript. Andall authors read and approved the final manuscript.Competing ... pseudoaneurysm waspunctured with a 21-gauge needle and 1500 U of human-derived thrombin was injected into the pseudoaneurysm(Figure 2). Total occlusion of the pseudoaneurysm wasconfirmed by DSA...
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Báo cáo khoa học:

Báo cáo khoa học: "Nucleated red blood cells in the blood of medical intensive care patients indicate increased mortality risk: a prospective cohort study" doc

... for death increased with the NRBC concentration and seems to decline again when the NRBCs have disappeared from the circulation. The prognosticsignificance of NRBCs was independent of other ... concentration of NRBCs in the blood, but the prognosis improved when the NRBC concentration decreased. In particular, after the firstdetection of NRBCs in blood and during the further course of intensive ... treatment.ConclusionThis is the first study in which the daily screening for NRBCs in the peripheral blood of patients in the medical intensive careunit was investigated with regard to its prognostic power for in- hospital...
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

... that invertase activity is increased during coldexposure in Rsch, whereas acitivity is reduced in C24after 7 days in the cold. Regarding the question of Systems biology of cold acclimation in ... showed significantly higheractivities of vInv at 0, 1 and 3 days of cold exposure. The activity of vInv in Rsch increased continuouslyduring cold exposure, and became significantly higherthan in ... cycling, weperformed in silico experiments, using the validatedmathematical model in terms of predictive metabolicengineering [18]. Replacing Vmaxvalues and k values in the C24 model with the...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

... and play a role in Tourette’s syndrome, nicotine addiction and Parkinson’sdisease. Thus, nAChRs modulating the dopamine releasegain increasing interest as drug targets, and identification of the ... subunits).cUnlessotherwise indicated, Kivalues for inhibition of epibatidine binding are shown; B, inhibition of a-BTX binding. d Indicates cases where K d values were obtained from oocyte-expressed receptors.Ó ... recent study based onsingle channel recordings and the use of a-conotoxins MIIand AuIB further dissected and correlated the combinato-rial and functional heterogeneity of the slowly decayingpopulation...
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Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf

Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf

... conforma-tional integrity. During protein unfolding ⁄ refolding, the addition of 2.5 protons (both E75 and E129 are the targets of protonation) results in SNase unfolding,with refolding at an early stage ... refolding[21]. Since then, many scientists have been interested in demonstrating this concept by using N-terminal andC-terminal fragments of SNase as models for the study of folding and unfolding pathways. ... center. The indole ring [26] of W140 may be the main target for the interactionwith both loop 2 and loop 3. Furthermore, from the protein folding scheme discussed previously [9],N « D D D 3,...
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Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf

Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf

... for the protein undergoing either aggregation or nativefolding.Analysis of the modulation of aggregation in bacte-ria was also of support in clarifying critical steps of oxidative folding of ... onformed aggregates triggering the degradation of mis-folded proteins while ClpB releases them from inclu-sion bodies (IBs) and presents unfolded polypeptidesto the (re)folding machinery. Altogether, ... detailedanalysis of the mode of building and of the structure of aggregates can be useful to dissect pathways andbottlenecks in the folding of specific proteins, forexample those containing...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc

Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc

... tissue retains the abilityto generate new adipocytes throughout life. Increased adipocyte number during aging has been implicated in the rising incidence and severity of obesity among the elderly ... of increased prolifera-tion or recruitment of preadipocytes [12], suggestingthat these cyclin-dependent kinase inhibitors areimportant in the regulation of adipocyte number. The S-phase kinase-associated ... Second, RMI1 deficiency signifi-cantly reduced food intake only under conditions of excess of energy input [19]. In addition, RMI1 expres-sion was significantly increased in the hypothalamusunder...
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Báo cáo khoa học: Neural retina leucine-zipper regulates the expression of Ppp2r5c, the regulatory subunit of protein phosphatase 2A, in photoreceptor development pdf

Báo cáo khoa học: Neural retina leucine-zipper regulates the expression of Ppp2r5c, the regulatory subunit of protein phosphatase 2A, in photoreceptor development pdf

... 5¢-CCC TGAAGC CAG GAT GAG CCG CAG GGA AAG-3¢ and5¢-TGG AGC TC G CTG ATT GGC CAG AAG CTG CAA-3¢) was used for the following EMSA assay. The DNAÆpro-tein binding reaction was conducted in a mixture ... 5¢-TCT TGG ACACGG TAG CAG AG-3¢; Ppp2r5c, forward, 5¢-AGT ACCTGG GGA TTG GC-3¢; Ppp2r5c, reverse, 5¢-CAT GGCTTG ATA TAC AAC GC-3¢; Gapdh, forward, 5¢-GGGCAC TTA CGG GTG TTA GA-3¢; Gapdh, reverse, ... 5¢-TCA GAG GAA GAG GTGTGT GTG-3¢. Amplified Nrl cDNA was introduced into the pCRII–TOPO vector (Invitrogen), and the Nrl clonewas verified by DNA sequencing. Nrl-full length cDNAwas subcloned into...
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