... disease duration, with a mean duration of 9.3 years. ATA-positive patients had a mean disease duration of 8.0 years, and ARA-positive patients and Ab-Neg patients had disease durations of 5.4 years ... whichproduce cytokines and chemokines that induce tissueAb-Neg: antibody-negative; ACA: anti-centromere antibody; ARA: anti-RNA polymerase antibody; ATA: anti-topoisomerase antibody; ELISA: enzyme-linked ... IL-10, and IL-13 in patients with systemic sclerosis. J Rheumatol 1997, 24:328-332.11. Sato S, Hanakawa H, Hasegawa M, Nagaoka T, Hamaguchi Y, Nishijima C, Komatsu K, Hirata A, Takehara K: Levels...