The Fetal Matrix: Evolution, Development and Disease - part 10 doc

... J. E. and Gluckman, P. D. Growth, metabolic and endocrine adaptations to fetal under- nutrition. In Fetal Origins of Cardiovascular Disease and Lung Disease. Lung Biology in Health and Disease, ... et al. Fetal growth and coronary heart disease in South India. Lancet 348 (1996), 1269–73. Stevens, L. M. and Landis, S. C. Developmental interactions between sweat glands...

Ngày tải lên: 11/08/2014, 11:22

... devel- opment and recorded his findings. From his observations, he recognised that the health of the fetus and the subsequent child depended on the health of the mother. Two -and- a-half thousand ... disciplines, from theoretical biology to health policy and economics. As we discussed in the preface, there has been a large gulf between the theoretical and evolutionary bio...

Ngày tải lên: 11/08/2014, 11:22

... University Press The Edinburgh Building, Cambridge CB2 8RU, UK First published in print format ISBN-13 97 8-0 -5 2 1-8 345 7-5 ISBN-13 97 8-0 -5 2 1-5 423 5-7 ISBN-13 97 8-0 -5 1 1-3 370 1-7 © P. Gluckman and M. Hanson ... Press. ISBN -1 0 0-5 1 1-3 370 1-9 ISBN -1 0 0-5 2 1-8 345 7-0 ISBN -1 0 0-5 2 1-5 423 5-9 Cambridge University Press ha...

Ngày tải lên: 11/08/2014, 11:22

... on the fetus but also on the placenta, and this may play a part in the development of the disease pre-eclampsia. The crucial point is that for about the first few weeks of human pregnancy the ... cell, the micro-environment is determined by the concentrations of sugar and oxygen and other nutrients in the blood stream and the tissue space surrounding the c...

Ngày tải lên: 11/08/2014, 11:22

... in siblings with the same mother and father. In half-siblings with the same mother the correlation is still high, but in half-siblings with different mothers but the same father there is no significant ... the Netherlands exposed to the near- famine conditions imposed by the Nazis in the winter of 1944/45. The effects of the poor and unbalanced diet of women during preg...

Ngày tải lên: 11/08/2014, 11:22

... Predictive adaptive responses and human disease Coronary heart disease Standardised mortality ratios (SMR) in 10 141 men and 5585 women 20 40 60 80 100 120 -5 .5 -6 .5 -7 .5 -8 .5 -9 .5 >9.5 Birth weight ... or the stress on the appearance of a hungry-looking predator. The adrenal gland is under the control of the pituitary gland, which makes the horm...

Ngày tải lên: 11/08/2014, 11:22

... from the mitochondria in the egg, and not via the sperm. So they fit the bill of DNA that is transmitted directly from grandmother to granddaughter. Second, the metabolic capacity of the grandchildren’s ... studied the licking and grooming habits of rat mothers with their pups and observed that there are mothers who groom their pups a lot, and those who do not. The pups...

Ngày tải lên: 11/08/2014, 11:22

... only in the offspring but also in the grand-offspring. We have already told the story of the Dutch Hunger Winterof1944/5 andexactly thesamething happenedthere :the grandchildrenborn to mothers who ... the paternal grandparent to the risk of diabetes in the grandson. Interestingly, the effect seemed to be confined to nutrition during the grandfather’s pre-pubertal growth phas...

Ngày tải lên: 11/08/2014, 11:22

... different nature 7 And the argument can continue back with diminishing effect to the great-grandmaternal and great-great- grandmaternal environments and so on. 8 The ovary develops in the first half ... diabetes, and in both India and Finland the pattern and timing of the adiposity rebound is partly determined prenatally. The data from Finland show similar influences o...

Ngày tải lên: 11/08/2014, 11:22

... Arabia msmonem@kfupm.edu.sa ISBN: 97 8-1 -4 02 0-6 07 2-4 e-ISBN: 97 8-1 -4 02 0-6 07 3-1 Library of Congress Control Number: 200892 1100 c  2008 Springer Science+Business Media B.V. No part of this work may be reproduced, ... being the scattering phase shift. From the boundary conditions of Eq. (29), ˜ S(r) is designated the “sine-like” J-matrix solution, and ˜ C(r...

Ngày tải lên: 27/06/2014, 05:20