The Fetal Matrix: Evolution, Development and Disease - part 5 potx

The Fetal Matrix: Evolution, Development and Disease - part 5 potx

The Fetal Matrix: Evolution, Development and Disease - part 5 potx

... from the mitochondria in the egg, and not via the sperm. So they fit the bill of DNA that is transmitted directly from grandmother to granddaughter. Second, the metabolic capacity of the grandchildren’s ... studied the licking and grooming habits of rat mothers with their pups and observed that there are mothers who groom their pups a lot, and those who do not. The pups...
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The Fetal Matrix: Evolution, Development and Disease - part 1 ppt

The Fetal Matrix: Evolution, Development and Disease - part 1 ppt

... Press The Edinburgh Building, Cambridge CB2 8RU, UK First published in print format ISBN-13 97 8-0 -5 2 1-8 3 45 7 -5 ISBN-13 97 8-0 -5 2 1 -5 423 5- 7 ISBN-13 97 8-0 -5 1 1-3 370 1-7 © P. Gluckman and M. Hanson 20 05 2004 Information ... without the written p ermission of Cambrid g e University Press. ISBN-10 0 -5 1 1-3 370 1-9 ISBN-10 0 -5 2 1-8 3 45 7...
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The Fetal Matrix: Evolution, Development and Disease - part 2 ppsx

The Fetal Matrix: Evolution, Development and Disease - part 2 ppsx

... on the fetus but also on the placenta, and this may play a part in the development of the disease pre-eclampsia. The crucial point is that for about the first few weeks of human pregnancy the ... cell, the micro-environment is determined by the concentrations of sugar and oxygen and other nutrients in the blood stream and the tissue space surrounding the c...
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The Fetal Matrix: Evolution, Development and Disease - part 3 pps

The Fetal Matrix: Evolution, Development and Disease - part 3 pps

... in siblings with the same mother and father. In half-siblings with the same mother the correlation is still high, but in half-siblings with different mothers but the same father there is no significant ... the Netherlands exposed to the near- famine conditions imposed by the Nazis in the winter of 1944/ 45. The effects of the poor and unbalanced diet of women during pre...
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The Fetal Matrix: Evolution, Development and Disease - part 4 ppsx

The Fetal Matrix: Evolution, Development and Disease - part 4 ppsx

... adaptive responses and human disease Coronary heart disease Standardised mortality ratios (SMR) in 10 141 men and 55 85 women 20 40 60 80 100 120 -5 .5 -6 .5 -7 .5 -8 .5 -9 .5 >9 .5 Birth weight (pounds) SMR 20 40 60 80 100 120 -5 .5 ... (pounds) SMR 20 40 60 80 100 120 -5 .5 -6 .5 -7 .5 -8 .5 -9 .5 >9 .5 Birth weight (pounds) SMR...
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The Fetal Matrix: Evolution, Development and Disease - part 7 ppt

The Fetal Matrix: Evolution, Development and Disease - part 7 ppt

... only in the offspring but also in the grand-offspring. We have already told the story of the Dutch Hunger Winterof1944 /5 andexactly thesamething happenedthere :the grandchildrenborn to mothers who ... the paternal grandparent to the risk of diabetes in the grandson. Interestingly, the effect seemed to be confined to nutrition during the grandfather’s pre-pubertal growth ph...
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The Fetal Matrix: Evolution, Development and Disease - part 8 pot

The Fetal Matrix: Evolution, Development and Disease - part 8 pot

... different nature 7 And the argument can continue back with diminishing effect to the great-grandmaternal and great-great- grandmaternal environments and so on. 8 The ovary develops in the first half ... PARs, the fetal environment can only shift more slowly. The first developmental signals to which the fetus is exposed occurred within the grandmother’s uterus when the...
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The Fetal Matrix: Evolution, Development and Disease - part 9 doc

The Fetal Matrix: Evolution, Development and Disease - part 9 doc

... devel- opment and recorded his findings. From his observations, he recognised that the health of the fetus and the subsequent child depended on the health of the mother. Two -and- a-half thousand ... health policy and economics. As we discussed in the preface, there has been a large gulf between the theoretical and evolutionary biolo- gists on one hand and medical scien...
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The Fetal Matrix: Evolution, Development and Disease - part 10 doc

The Fetal Matrix: Evolution, Development and Disease - part 10 doc

... 190n grasshoppers 5 grooming, rats 113, 156 growth adolescence 57 after birth 55 –8 catch-up 56 , 141 excessive 211–12 fetal experience 141 childhood 56 infancy 56 length 56 optimal curve 204 patterns and disease ... (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 35 (1992), 59 5–601. Hales, C. N. and Barker, D. J. The thrif...
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The J-Matrix Method Development and Application potx

The J-Matrix Method Development and Application potx

... being the scattering phase shift. From the boundary conditions of Eq. (29), ˜ S(r) is designated the “sine-like” J-matrix solution, and ˜ C(r) the “cosine-like” J-matrix solution. The sine-like ... Arabia msmonem@kfupm.edu.sa ISBN: 97 8-1 -4 02 0-6 07 2-4 e-ISBN: 97 8-1 -4 02 0-6 07 3-1 Library of Congress Control Number: 2008921100 c  2008 Springer Science+Busines...
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