... autoregulation of RIN itself during ripening.Results In silico search of CArG boxes in the promoters of ripening-induced genes The rin mutant lacks expression of LeACS2, LeACS4,TBG4, LeEXP1, LeMAN4 ... levels of LeACO1, ETR3, PG andINV, while these genes are highly upregulated in thewild-type fruit [8,13,28,29], indicating that all of these genes are regulated directly or indirectly by RIN. ... transcriptional regulation of the cel l- wall-modifying genes and ACS genes, respectively. The con-trol of ethylene production by RIN during ripeningmeans that RIN is also indirectly responsible for...