báo cáo khoa học: " Uncharacterized conserved motifs outside

báo cáo khoa học: " Uncharacterized conserved motifs outside the HD-Zip domain in HD-Zip subfamily I transcription factors; a potential source of functional diversity" docx

... two are almost indispensable: a DNA-binding domain and a protein-proteininteractiondomainwhich mediates activation or repression of transcription [1]. HD-Zip proteins are transcription factors ... proteins have a mod- ular structure and exhibit at least two types of domains: a DNA binding domain and a protein-protein interaction domain which mediates, directly or ind...

Ngày tải lên : 11/08/2014, 11:21

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Báo cáo khoa học: Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death ppt

... brain. In the course of cerebral ischemia (i. e. stroke, trauma, cardiac arrest), abnormal levels of the excitatory amino acid glutamate build up in the brain, causing ‘axon-sparing’ excitotoxic ... University of Calabria, Arcavacata di Rende (CS), Italy A wealth of information has accumulated to date con- cerning the basic mechanisms underlying post-ischemic neuronal de...

Ngày tải lên : 07/03/2014, 03:20

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Báo cáo khoa học: Huntington’s disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases pptx

... polyglutamine tract [28]. Ataxin-1 inclusion formation is dictated by signaling and post-translational phosphorylation of a single serine in ataxin-1 at position 776, regardless of polyglutamine ... Disease Foundation, (HDF) USA, the Cure Huntington’s Disease Initiative (CHDI) USA, the Huntington’s disease Society of America (HDSA), the Huntington’s Society of Canada and...

Ngày tải lên : 23/03/2014, 07:20

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Báo cáo khoa học: Annexin A2 binds to the localization signal in the 3¢ untranslated region of c-myc mRNA ppt

... function. There is now evidence that in an increasing number of speciﬁc cases this not only involves targeting signals within proteins, but also signals in mRNAs resulting in their localization and ... The data indicate a novel functional role for the RNA-binding properties of annexin A2 in perinuclear localization of mRNA and the association with the cytoskeleton....

Ngày tải lên : 30/03/2014, 15:20

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Báo cáo khoa học: " Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas – a retrospective evaluation of the Homburg experience in the years 1995–2007" pdf

... Gammamed1 2i high-dose- rate afterloading machine (Varian Medical Systems, Haan, Germany) with a Ir-192 source and a nominal activity of 10 Ci which was situated in a special room in direct vicin- ity ... primary sarcomas, in the remaining nine the disease had recurred. The mean age at the beginning of treatment was 56 years, the mean Karnofsky performance status 9...

Ngày tải lên : 09/08/2014, 10:20

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báo cáo khoa học: " Part II, Provider perspectives: should patients be activated to request evidence-based medicine? a qualitative study of the VA project to implement diuretics (VAPID)" potx

... dis- cussions: Interviewe r: ‘What do you think in general about promoting things such as new guideline therapies through patient-initiated interventions taking information to the patient and having them bring ... intervention as facilitating change in a manner more unique to patient activation, by ‘empowering’ patients and ‘align- ing’ the ‘priorities’ of the patient and prov...

Ngày tải lên : 10/08/2014, 10:22

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báo cáo khoa học:"Maximum occlusal force and medial mandibular flexure in relation to vertical facial pattern: a cross-sectional study" pdf

... that maximum bite force in the molar area was not associated with facial characteristics in Scandinavian children and young adults, although they found that bite force in the incisor region was ... image was cali- brated with the digital calipers image (10 mm-width). Intermolar distance was measured in triplicate for each image and averaged. MMF in maximum opening was calculat...

Ngày tải lên : 11/08/2014, 23:22

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Báo cáo khoa học: " Hepatitis C Virus entry: the early steps in the viral replication cycle" ppt

... intracellular loop, and two intracellular tails (the C and N-termi- nus). Within the family of mammalian claudins the N- terminal is ~7 amino acids, the first extracellular loop (ECL1) is ~50 amino acids, ... author of this manuscript. Author information After finishing high school in Tucson, Arizona, the author enlisted as an infantryman in the United States Army. After...

Ngày tải lên : 12/08/2014, 04:21

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Báo cáo khoa học: Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A pdf

... DISCUSSION Identi®cation of two A subunit-binding domains in B5 6a To determine the minimal r egion of B56 that interacted with the PP 2A subunit, we utilized an in vitro binding assay using GST -A subunit ... in the individual protein sequence, followed by the GenBank accession number. Amino acids that are invariant are highlighted in black. Identical residues conse...

Ngày tải lên : 08/03/2014, 10:20

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