báo cáo khoa học: " Patterns of sequence polymorphism in the fleshless berry locus in cultivated and wild Vitis vinifera accessions" pdf
... for the 69 genome fragments at the top of chromosome 18 in the cultivated and the wild compartmen t of Vitis vinifera and details of the shared and specific insertions/deletions (INDELs) and ... from the flb region in wild and cultivated grapevines. Venn diagram showing the distribution of the 554 non-redundant SNPs found in the 948 kb reg...
Ngày tải lên: 11/08/2014, 11:21
... to the a-globin gene locus dur- ing the differentiation of erythroid cells. The regula- tory elements located upstream of the a-globin genes also appear to initiate the activation of the gene locus. However, ... gene promoters and to the LCR of the murine b-globin gene locus in MEL cells. (A) Schematic repre- sentation of the murine b-globin gene locus....
Ngày tải lên: 07/03/2014, 12:20
... constants with the wild- type PR (Table 3). The mutated residues in this sequence are in the outer regions of the cleavage site sequence recognized by the PR, and the respective S4 and S3 binding sites ... 2). Increasing the concentration of the NC/p1 substrate above the K m resulted in a decreased velocity, suggesting the possibility of increased nonp...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: Characterization of sequence variations in human histone H1.2 and H1.4 subtypes pptx
... confirm the H1.2 Ala17Val sequence variation, a 183 bp PCR product was amplified in the 5¢-UTR, and the start of the coding sequence of the H1.2 gene cor- responding to the N-terminal tail of the ... tail and the binding of H1.4 to chromatin, as arginine offers additional hydrogen-bonding abilities to DNA as compared to lysine. Lysine 173 in H1.4 is situated...
Ngày tải lên: 30/03/2014, 20:20
báo cáo khoa học: " Patterns of research utilization on patient care units" pps
... Pitts N: Changing the behavior of healthcare professionals: The use of theory in promoting the uptake of research findings. J Clin Epidemiol 2005, 58:107-12. 4. The Improved Clinical Effectiveness ... participated in conceptualiza- tion of study, securing grant funding, in the start-up of the study (with data collection) and served as a lead investiga- tor for t...
Ngày tải lên: 11/08/2014, 16:21
Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"
... intensive care unit during the studies noted that interns in the intervention schedule “often knew very little about the patients who had been admitted the night before” and that the “intern coming on at ... errors.” Differences in the incidence of serious errors were analyzed using rates (per patient-day), and therefore the fact that there were more patient-days in...
Ngày tải lên: 25/10/2012, 10:45
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a coupled oscillator-based mechanism in smooth muscle ppt
... typically in the range 2–3 mm [26]. Finding experimental evidence that electrical cou- pling is the key ‘spring’ interlinking the Ca 2+ stores has involved repeating the decoupling experiment of Fig. ... composed of a large number of Ca 2+ store oscillators. In this simulation, the intrinsic frequencies of oscilla- tors are different from each other, and as the [Ins(...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Proteolysis of Pseudomonas exotoxin A within hepatic endosomes by cathepsins B and D produces fragments displaying in vitro ADP-ribosylating and apoptotic effects doc
... determined. Finally, we assign an important role to the endosomal acidic cathep- sins B and D in increasing the in vitro transfer of the ADP-ribosyl moiety of NAD + to EF-2 by ETA, but not in the ... revealed the N-terminal sequence of ETA (AEEAFDL), suggesting that the cleavage sites are located within the C-terminal region of the toxin. N-terminal sequence...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area ppt
... was preincubated for 10 min and assayed in the presence of the given concentrations of the hydro- phobic probe bis-ANS, using TO as substrate. The activity of phos- phorylated HSL in the TO assay ... exposes and ⁄ or increases the lipid-binding area of the enzyme. A direct demonstration of this presumed conformational change will have to await the solving of...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae pptx
... vitro activity of acyl-CoA:ergosterol acyltransferase was determined in an are1 deletion background. The enzyme activity in the ste20D strain and the cla4D strain was indistinguishable from that in the wild- type ... lethal, indicating that CLA4 and these genes, encod- ing proteins involved in sterol synthesis, may function in the same pathway(s) [25]. It is not cle...
Ngày tải lên: 18/02/2014, 13:20