báo cáo khoa học: "Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells" potx

... 13 of 13RESEARC H ARTIC LE Open AccessTrichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition ... viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells. BMC Plant Biology 2010 ... 3). Alamethicin resistance of tobacco cells is mainly due to the effect of cellulase In the initial experiments, cells were treated with a com-bination of cellulase and macerozyme in mannitol...

Báo cáo khoa học: "Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy" ppt

... visualized using 3-3 diaminobenzidine for 5 minutes.Slides were then rinsed in water, lightly counterstained in filtered Mayer’s hematoxylin, rinsed, dehydrated, cleared,and mounted. The cells of interest ... (WKF)who was blinded to clinical information. Sections werescored by multiplying the avera ge staining intensity seenon a scale of 0 to 3+ by the percentage of cells that werepositive to any degree, ... assistance of Kay C. Chao for performing the KRAStesting, Chris Civalier for performing the BRAF testing, Nana Feinberg forperforming the IHC testing, and the Anatomic Pathology Core Laboratory.This...

Báo cáo khoa học: " Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit"

... remit of the local ethics committee. Prior to introduction of CPOE, local standards of prescribing existedspecifying the tenets of good practice, including the avoid-ance of the use of abbreviations.An ... Most of the errors were minor in outcome, although two non-inter-cepted errors with CPOE led to an increased length of stay orincreased monitoring. In the first case, an anuric patient onhaemofiltration ... of the types of errors appeared to change with CPOE; of particular concern was the finding that all three of the majorintercepted errors arose with CPOE. In our study, CPOEclearly reduced the...

Tài liệu Báo cáo khoa học: High afﬁnity copper binding by steﬁn B (cystatin B) and its role in the inhibition of amyloid ﬁbrillation docx

... are central to copper binding in many proteins they probably formpart of the copper binding sites in this protein.Although there are four histidines in the C-terminal,another histidine is present ... partitioning of the proteininto an aggregated state. The effect of copper binding on the secondary struc-ture was determined using CD in the far UV. To prepare proteins without Cu2+, part of each ... important in the brain, there-fore the role of copper binding or loss of its bindingcould be related to speciﬁc cerebellar function(s) of steﬁn B [18], which remains to be seen by more in vivostudies.Steﬁn...

Báo cáo khoa học: Identiﬁcation and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf

... processes. In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activityinvolved in the oxidative stress in S. solfataricus. To detect differences in the response ... periods of time(Fig. 3). As shown, the addition of stressors to the cul-tures inhibits growth without killing the cells. The hybridizing band in the northern analysisshowed the expected size of ... types of thioredoxins were found. In this study we examined the involvement of the peroxiredoxin Bcp2 in oxidative stress in the hyper-thermophilic aerobic archaeon Sulfolobus solfataricus.Furthermore,...

Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

... C1 deﬁnes the domain closest to the amino terminal end and C2deﬁnes the domain closest to the cell membrane. Acomparison of the inferred amino acid sequence of the C1 and C2 domains reveals ... of the cytoplasmic domain were carried out,making use of the whole receptor intracellular part amputa-ted of its highly variable C-terminal domain after the terminal conserved arginine of the ... receptors are in bold andunderlined, and the cysteine knot is boxed.Also boxed are the transmembrane domain, the ATP binding site, the L45 loop and the serine ⁄ threonine kinase domain. (B) The implied...

báo cáo khoa học: "Sustained complete remission of human epidermal growth factor receptor 2-positive metastatic breast cancer in the liver during long-term trastuzumab (Herceptin) maintenance therapy in a woman: a case report" docx

... years of full remission in the liver but relapsed in the central nervous system within t wo months of with- drawal of trastuzumab maintenance therapy [9].Support for the importance of maintaining ... 34-year-old Cau-casian woman, with no histor y of hormone therapy,smoking, drinking, or a family history of breast cancer,presented with a lump in the center of her right breast. The axillary and neck ... mab (Herceptin) in combination with vinorelbine and gemcitabine. The patientremains in complete remission seven years later and continues to receive trastuzumab as maintenance therapy.Conclusion:...

báo cáo khoa học: "A consensus linkage map for molecular markers and Quantitative Trait Loci associated with economically important traits in melon (Cucumis melo L.)" pptx

... using the bin mapping strategy [15] wereincluded in the integrated map. The expected interval for position of the markers in centiMorgans (cM) in the integrated map based on the markersdefining ... located on the melonintegrated map. Excel spread sheet containing the definition of the QTLlocated on the melon integrated map. QTL are designated according to the following rules: the first ... All the individual maps, the integratedmap, marker and QTL information are available atICuGI web site (http://www.icugi.org). Researchersinterested in including their QTL data into the inte-grated...

báo cáo khoa học:" Short-term effects of amelogenin gene splice products A+4 and A-4 implanted in the exposed rat molar pulp" pptx

... capacity to be involvedsimultaneously in each of the three facets. Altogether, theyare prominently involved in the formation, structure andmineralization of dentin and bone. In addition, some of them ... implantationinto the dental pulp which would in theory implicatetheir differentiation to odontoblast-like progenitors. The kinetics of the reaction supports the interpretation that in this case ... relative to PCNA indi-cate that while implantation of the beads alone does notimpair the steady growth of the cells in the vicinity of the beads, the addition of A+4 or A-4 initially stimulates the cell...

Báo cáo khoa học: "Bovine viral diarrhea virus NS4B protein is an integral membrane protein associated with Golgi markers and rearranged host membranes" ppsx

... known to replicate itsgenome in association with the outer mitochondrial membrane [36]. Nevertheless, the involvement of NS4B in BVDV cytopathogenicity [27] and the induction of apoptosis by cytopathic ... most of the virusremaining in the cells may represent immature virus par-ticles. To ascertain the rate of RNA synthesis during BVDV infec-tion, MDBK cells were infected at MOI of 0.1 and total ... significance of such findingswill be discussed.ResultsKinetics of BVDV RNA synthesis in infected MDBK cells The function of NS4B protein in BVDV replication ispoorly understood. However, the findings...

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