... elongation of the prenyl chain of the finalproduct. In addition, two amino acids inserted into FARM,which occurs in FPSs and GGPSs from bacteria and plants,are also considered to be involved in the ... whilesmaller amino acid residues such as valine, alanine, serine,cysteine or glutamic acid are conserved in the longer-chain(all-E) prenyl diphosphate synthases and in the short-chainenzymes of other ... the area, including FARM and severalamino acids upstream of it, as the CLD (chain-lengthdetermination) region and proposed a classification of theseenzymes based on the patterns of such characteristic...