... patient had many of the clinical and anatomic findings typical of OTCS: the dysmorphic face, white matter alteration, as described by Lalatta [4] and by Azimi [5], cerebral hemorrhage [3] and hearing ... rheumatology con- cluded that patient 1 of Optiz had a possible connective tissue abnormal ity and increased vascular fragility that started the catastrophic cascade t...
Ngày tải lên: 10/08/2014, 23:21
... curves the para- meters b and a were varied and R was kept fix at 0.1, 0.5 and 1, respectively. The fitted EAR values were compared to the original data. The a- and R-values, and a- andb-values ... γ a ln agea 7 0 (2) In this form the fit parameters are gender-averaged and centered at an age at expo- sure of 30 years and an attained age of 70 years. Th...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "Positive end-expiratory pressure at minimal respiratory elastance represents the best compromise between mechanical stress and lung aeration in oleic acid induced lung injury" pps
... poorly aerated and hyperinflated areas. Study limitations A limitation of the present study is that the lung morphological analysis was based on a single slice of the CT scan taken at the juxta-diaphragmatic ... normally aerated areas, light grey squares indicate poorly aerated areas, and black triangles indicate non-aerated areas. The filled and open symbols indicate...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: " Bullet-induced synovitis as a cause of secondary osteoarthritis of the hip joint: A case report and review of literature" ppt
... conceived of the case, drafted the manuscript and did the literature review. MU helped in drafting and reviewed the case. MAW reviewed the case, helped in drafting the report. YJS helped in literature ... several factors. Firstly the initial trauma may cause fractures of articular bone, leading to an incon- gruous and irregular joint surface. Motion of such su...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes docx
... 2035 isomerization of aspartate residues [6]. Major targets of these alterations, also called Ôprotein molecular fatigue damageÕ [7], are cytoskeletal components, such as ankyrin and bands 4.1 and 4.2, as ... concentration was determined spectro- photometrically [24]. PK activity was evaluated as a cell-age marker by the method of Beutler et al.[16]. Statistical analysis S...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo y học: "B cells as a therapeutic target in autoimmune disease" doc
... cells. In addition, signaling via CD20 Commentary B cells as a therapeutic target in autoimmune disease Jörg J Goronzy and Cornelia M Weyand Departments of Medicine and Immunology, Mayo Clinic, ... declared. Acknowledgements Supported in part by grants from the National Institutes of Health (AR 42457, AR 41974 and AI 44142) and by the Mayo Foundation. We thank James W Fulb...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Rheumatoid arthritis as a hyper-endoplasmic reticulumassociated degradation disease" pdf
... to understand the role of the ERAD system in human RA and to define other as yet unknown aspects of RA before the design of any ERAD-based therapy for the disease. Competing interests The author(s) ... Marianna University School of Medicine, Kawasaki, Kanagawa, Japan 2 Rheumatology, Immunology and Genetics Program, Institute of Medical Science, St Marianna University...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Plasma gelsolin as a biomarker of inflammation" doc
... dogma has expanded to now accommodate the convincing observations that plasma gelsolin can bind a variety of potentially inflammatory moieties, and can thereby modulate the exuberance of the host ... actin may be the primary cause of gelsolin depletion, the biologic imperative for gelsolin could entail the modulation of several inflammatory mediators as much as...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study" potx
... study, although uTWEAK levels did increase as the flare approached, the peak was at the time of the flare rather than in advance of it. As the measurements were based on a relatively small group of ... levels and disease activity over time. Classification of systemic lupus erythematosus activity status LN activity was evaluated based on a subset of the Systemi...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Obstructive azoospermia as an unusual complication associated with herniorrhaphy of an omphalocele: a case repor" ppt
... matures. Omphalocele is a disease of neonates involving the herniation of intra-abdominal organs because of an abdominal wall defect, and emergency operations are gen erally required in most cases. The reported ... procedure and reported the case. KY and AK interpreted and analyzed the findings. OO participated in the diagnostic and therapeutic decisions. KO and...
Ngày tải lên: 10/08/2014, 23:21