... converts adenosine and 20-deoxyadeno-sine to inosine and 20-deoxyinosine, respectively. Thosecomponents are generated in large amounts from apopto-tic cells in the thymus, marrow, and lymph nodes ... reported in 19 72 [2]. Infants withthis syndrome are lymphopenic and have profounddeficiencies of T and B cell numb ers and function.Adenosine deaminase is an important deaminatingenzyme, which ... lymphopenic and died of infection before their second birthday. In theensuing years, differences in inheritance patterns werenoted, indicating causal heterogeneity of this condition. In many families,...