Báo cáo y học: "Kinetics and isotype profile of antibody res

Báo cáo y học: "Kinetics and isotype profile of antibody responses in rhesus macaques induced following vaccination with HPV 6, 11, 16 and 18 L1-virus-like particles formulated with or without Merck aluminum adjuvant" ppt

... of Immune Based Therapies and Vaccines Open Access Original research Kinetics and isotype profile of antibody responses in rhesus macaques induced following vaccination with HPV 6, 11, 16 and ... Immunoassay (cLIA). Sera from rhesus macaques immunized with 2 µg each of HPV 6, 11, 16 and 18L1-VLPs formulated with Merck Aluminum...

Ngày tải lên : 11/08/2014, 10:23

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Báo cáo y học: "The matrix-forming phenotype of cultured human meniscus cells is enhanced after culture with fibroblast growth factor 2 and is further stimulated by hypoxia" pdf

... content of the papain digest was determined by measuring Hoechst 33258 dye (Sigma) binding with a Hoeffer Dyna Quant 200 fluorometer. Glycosaminoglycans were assayed in the papain digest by using ... [22] of meniscus cells in vitro and also to maintain the ability of mon- olayer expanded chondrocytes to redifferentiate [ 16, 2 3]. Materials and methods Cell isolation and exp...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Response to: Cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection – authors’ reply" ppt

... (ACS) in this study was prepared in a GMP (good manufacturing practice) facility in strict accordance with the guidelines supplied by the manufacturer (Orthogen, Düsseldorf, Germany) and was injected ... to determine the cytokine levels before and during ACS treatment. We showed that, 3 days after injection, cytokine levels were at baseline and had no secondary eﬀ ects on...

Ngày tải lên : 12/08/2014, 15:22

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Báo cáo y học: "The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challeng" ppt

... been reported. Therefore, we undertook this important and timely study of the gene expression analysis in AA. In this study, we examined the gene expression profiles of the draining lymph node ... molecules (Tables 1 and 2). Not surprisingly, the Bhsp65 -induced gene expression profile mostly reinforced the immune-based and inflammatory nature of AA. The expression lev...

Ngày tải lên : 12/08/2014, 18:20

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Báo cáo y học: "An open pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine: preliminary results on tolerability and clinical effects" ppsx

... thus continuing the study with zonisamide 75 mg/day once a day augmentation and maintaining duloxetine 60 mg/ day once a day. By definition, week 12 HAM-D t otal scores were significantly lower ... neurotransmitters involved in the patho- physiology of depression, including dopamine and seroto- nin [11-13]. Therefore, in consideration of a partial pharmacodynamic overlap between...

Ngày tải lên : 09/08/2014, 01:21

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Báo cáo y học: "Magnetic resonance imaging changes of sacroiliac joints in patients with recent-onset inflammatory back pain: inter-reader reliability and prevalence of abnormalities" potx

... therefore be ascertained in future, by following the patients longitudinally and obtaining more data, which will occur in this cohort. The development and choice of an appro- priate scoring system ... reported a history of both uveitis and IBD, and one patient reported psoriasis and IBD. Of the 25 patients (37%) with a family history of AS, four patients had a medica...

Ngày tải lên : 09/08/2014, 07:20

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$Báo cáo y học: "Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity" pot$

Báo cáo y học: "Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity" pot

... respectively, of predicting withdrawal of infliximab therapy due to inefficacy (Table 3). Taking into account the 13.6% a priori chance to withdraw therapy due to inefficacy, a DAS28 of at least ... 511 patients with long-standing refractory rheumatoid arthritis treated with intravenous infusions of infliximab 3 mg/kg at weeks 0, 2, 6, and 14 and every 8 weeks thereafter for...

Ngày tải lên : 09/08/2014, 08:22

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Báo cáo y học: "RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro" pps

... rapidly in mouse osteoclasts following cytokine starvation but are restored by pro-survival factorsMcl-1 levels decrease rapidly in mouse osteoclasts following cytokine starvation but are restored ... clodronate or alendronate for up to 48 hours in the absence or presence of RANKL. Changes in cell morphology and induction of apoptosis were examined by scanning electron m...

Ngày tải lên : 09/08/2014, 14:20

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Báo cáo y học: " Phase IIb randomized trial of adjunct immunotherapy in patients with first-diagnosed tuberculosis, relapsed and multi-drug-resistant (MDR) TB" doc

... which following chemical- and heat inactivation was formulated into an oral pill according to proprietary technology developed by us [6]. It is well known that one third of people carry M. tuberculosis ... of revaccination with BCG in early childhood on mortality: randomised trial in Guinea-Bissau. BMJ 2010, 340:c671. 32. Silin DS, Lyubomska OV, Jirathitikal V, Bourinbaiar A...

Ngày tải lên : 11/08/2014, 08:21

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Báo cáo y học: " The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages" doc

... hibition of two steps in the NFB pathway by modifying specific cysteine residues in IKKa and in the p50-subunit resulting in the inhibition of nuclear translocation and DNA-binding to the iNOS promoter. ... part of host defenses against microorgan- isms. Macrophages are the main proinflammatory cells responsible for invading pathogens by releasing proinflammatory mediator...

Ngày tải lên : 11/08/2014, 08:22

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