Báo cáo y học: "Tumor-infiltrating effector cells of α-galactosylceramide-induced antitumor immunity in metastatic liver tumor" pdf

... nod-ules, since MC38 cells sometimes showed diffuse invasiveFlow cytometry analysis of tumor-infiltrating cells (I)Figure 2Flow cytometry analysis of tumor-infiltrating cells (I). Leukocytes were ... AccessOriginal researchTumor-infiltrating effector cells of α-galactosylceramide-induced antitumor immunity in metastatic liver tumorTakuya Osada*1,2, Hirokazu Nagawa1 and Yoichi Shibata2Address: ... enhance NK cell infiltration into tumornodules. This reagent may also elicit more profound immunity, including acquired immunity, by inducing theinfiltration of DC and CD8+T cells into tumor nodules.These...

Báo cáo y học: "Women’s experiences of wearing therapeutic footwear in three European countries" pdf

... replacement of existingfootwear is not as noticeable as it closely resembles thefootwear that they would normally wear. Contrastingly,forthewomen,thelossoffemininityimposedbytheappearance of the footwear ... will not like me any more ”. Catalina (Spain)“Ican’t walk normally If you shuffle around peoplenotice and (thinks for a time) it shows in yourface pain shows in your face makes you look oldand ... vital in influen-cing whether they engaged in the use of therapeuticfootwear. This relationship is described as a partnership in which sharing of information, support, and empathyis necessary...

Báo cáo y học: "Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients" doc

... Luton, UKECD, phycoerythrin-Texas Red-x; FITC, fluorescein isothiocyanate; PC5, phycoerythrin-cyanin 5.1; PC7, phycoerythrin-cyanin 7; PE, phycoerythrinUrbanowicz et al. Respiratory Research 2010, ... predominantly Th1-type cytokines [21-24],which could influence t he cytokine milieu within thelung to one which is pro-inflammatory. Interestingly, nodifference in cytotoxic ability of the ... assay.Conclusion In summary, we have shown an increased propo rtion of three types of cytotoxic cells, namely C D8+T lympho-cytes, NK and NKT-like cells, in the induced sputum of COPD subjects...

Báo cáo y học: " Altered effector function of peripheral cytotoxic cells in COPD" doc

... IgG2b δG9 Becton Dickinson, Oxford, UKECD, phycoerythrin-Texas Red-x; FITC, fluorescein isothiocyanate; PC5, phycoerythrin-cyanin 5.1; PC7, phycoerythrin-cyanin 7; PE, phycoerythrinPublish with ... the synergistic activity of the apoptosis inducing granzyme B to kill within the 4-hour window of the assay. Granzyme B only cells couldkill through the endocytotic uptake of granzyme B by thetarget ... extremely low number of invariant NKT cells in theCytotoxic activity of CD56+ cells in the presence of different concentrations of an anti-perforin antibody (A), an anti-granzyme B antibody (B)...

Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx

... 2-arachidonoylglycerol (2-AG), the cannabinoid CB1and CB2receptors, and one of the enzymes mostlyresponsible for endocannabinoid hydrolysis, the fatty acidamide hydrolase (FAAH). By using a very ... theendocannabinoids, have been detected in several bloodimmune cells, including monocytes/macrophages,basophils and lymphocytes. However, their presence in dendritic cells, which play a key role in the ... described in vitro [9]. A reduction of the cytolytic activity of naturalkiller cells and of antigen presentation was also observed,again in vitro [9].The endocannabinoid system, comprising membranereceptors...

Báo cáo y học: "Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathie" doc

... killer cells to the site of inflammation. In conclusion, a network of interactions between cytokines,chemokines and proteases controls the recruitment of leuko-cytes. Blockage of a single cytokine ... Conings R,Opdenakker G, Heremans H, Billiau A: Induction of monocytechemotactic proteins MCP-1 and MCP-2 in human fibroblastsand leukocytes by cytokines and cytokine inducers. Chemicalsynthesis ... thestudy.ResultsSynergistic induction of CXCL10 ligands in fibroblasts andendothelial cells by inflammatory cytokines.The lymphocyte chemotactic CXCR3 ligands are known to beinducible by IFNs, whereas...

Báo cáo y học: "IFN-gamma regulation of ICAM-1 receptors in bronchial epithelial cells: soluble ICAM–1 release inhibits human rhinovirus infectio" pptx

... A: Inhibition of interferon signalling by dengue virus. PNAS2003, 100(24):14333-14338.29. Lin RJ, Liao CL, Lin E, Lin Y: Blocking of the alpha interferon-induced Jak-Stat signalling pathway ... on cell type [9,10]. Crucially, thecourse of HRV infection can also be manipulated by thetypes and time kinetics of inflammatory cytokines in theimmediate cell milieu [11-13]. Of interest, ... monolayerswashed with PBS.HRV infection of NHBE cells To determine whether expression behaviour of ICAM-1isoforms in HRV-infected airway epithelial cells is influ-enced by IFN-γ pre-conditioning...

Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"

... 14distress syndrome within 30 days following inclusion.The secondary endpoint was overall survival within 30days following study inclusion. Outcomes were assessedduring hospital stay at days 3, ... available in 94.8% of patients. The most frequently missing covariate con-tained in the CURB65 score was urea which was missing in 19.1% of patients, primarily because it was only rarelymeasured in ... PCT. The primary end-point in thisnon-inferiority trial was a combined endpoint of adversemedical outcomes within 30 days following the EDadmission. A further predefined secondary objective wasthe...

Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

... distinct career pathway. Involving such physicians in medicalemergency teams will likely facilitate the dual roles of these as aclinical outreach arm of the intensive care unit and in identifyingproblems ... higherthan routine incident-reporting systems, but without requiringsubstantial investments of additional resources. Academic centersare increasingly recognizing engagement in quality improvement ... development of METs rose from observations that, in the majority of patients, premonitory signs and symptoms of cardio-pulmonary instability are often present hours before clinicaldeterioration [6]. By...

Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"

... drainage system of the frontal sinus depends on its embryologic development [2,13]. The drainage usually occurs directly into the frontal recess [14] or into the frontal recess by way of rudimentary ... age of 8 years, the top of the frontal sinuses is at the level of the orbital roof, and by the age of 10 years, the sinuses extend into the vertical portion of the frontal bone. The final adult ... usually found in individuals of the same age [11,12]. Because the left and right frontal sinuses develop independently, a significant asym-metry between these sinuses can arise in the same individual...

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