Báo cáo y học: "Development of a model of focal pneumococcal pneumonia in young rats" ppsx

... of a model of focal pneumococcal pneumonia in young rats Richard Malley* 1,2 , Anne M Stack 1 , Robert N Husson 2 , Claudette M Thompson 3 , Gary R Fleisher 1 and Richard A Saladino 1,4 Address: ... develop a model of Streptococcus pneumoniae pneumonia in Sprague- Dawley rats. We challenged three-week old Sprague-Dawley pups via intrapulmonary injection of S....

Ngày tải lên: 11/08/2014, 10:23

... joint inflammation improves. Rheumatoid cachexia may be an important risk factor for cardiovascular disease and excess mortality in RA. In this issue of Arthritis Research & Therapy, Elkan and ... issue of Arthritis Research & Therapy includes an important article on rheumatoid cachexia by Elkan and colleagues [1] demonstrating that cachexia remains common in rheumatoid arth...

Ngày tải lên: 09/08/2014, 14:20

... in high local concentrations in murine fibrosarcoma models of hyperalgesia [19], and was not seen in a non-sarcoma model (melanoma) [19]. Interestingly, local administra- tion of an endothelin -A receptor ... characteristic of potentially spe- cific inhibition as a means of alleviating cancer pain. In many cancers, invasion of the perineurium is necessary for the deve...

Ngày tải lên: 10/08/2014, 10:20

... in the same way as their mammalian counterparts [12], and they also bind to syntrophin [18]. dys-1 and dyb-1 mutants d isplay a similar behavioural phenotype c onsisting of hyperactivity, exagger- ated ... dystrobrevins, there a re several i ndications that they may play a role in signalling mechanisms. First, dystrobrevins are tyrosine-phosphorylated proteins [5,14]. Secondly, i...

Ngày tải lên: 08/03/2014, 23:20

... tumor samples and found somatic mutations in 24 genes, including APC, KRAS, SMAD4 and PIK3CA. A pairwise comparison of somatic variations in primary and metastatic samples indicated that many chromothripsis ... visualized by Circos software [38]. SNP-array analysis DNA from all 16 tumor and control samples was analyzed by Illumina Cyto12 SNP arrays according to standard proce...

Ngày tải lên: 09/08/2014, 23:20

... article as: Bhat et al.: Long-term myocardial recov ery after mitral valve replacement in noncompaction cardiomyopathy. Journal of Cardiothoracic Surgery 2011 6:124. Bhat et al. Journal of Cardiothoracic ... 10016, USA. Authors’ contributions AC, YO and TC analyzed and interpreted the patient data. TB, HB and ST were involved in doing the literature review and manuscript preparation a...

Ngày tải lên: 10/08/2014, 09:22

... Corresponding author Abstract Introduction: Hypocellular variants of acute myeloid leukemia are very rare and almost always occur in old aged patients. In contrast, hypocellular acute lymphoblastic ... best of our knowledge, hypocellular AML has not been reported in young and pediatric patients. There are many case series and individual case reports of hypoplastic acute leukemi...

Ngày tải lên: 11/08/2014, 19:21

... mean of three acceptable maneuvers is reported as the data point. Cytokine Measurements Plasma and lung lavage cytokines were measured using the Luminex human cytokine multiplex-25 bead array assay ... execu- tion and aided in the preparation of the manuscript and the statistical analysis of the data. MR contributed to the study design and analysis of data. JC helped to design the s...

Ngày tải lên: 12/08/2014, 14:20

... Tsuda, T., K aya, S., Yokoyama, T., Hayashi, Y. & Taniguchi, K. (1998) ATP and acetyl phosphate induces m olecular events near the ATP binding site and t he membrane dom ain of N a + , K + -ATPase:Thetetramericnatureoftheenzyme.J. ... S., A be, K., Taniguchi, K., Katoh, T ., Yazawa, M., Hayashi, Y. & Ma Ê rdh, S. (1999) Acid-labile ATP and/or ADP/P i binding to the tetraprotom...

Ngày tải lên: 24/03/2014, 00:21

... Lucia, Australia A novel photoactivatable analog of antisauvagine-30 (aSvg- 30), a specific antagonist for corticotropin-releasing factor (CRF) receptor, type 2 (CRF 2 ), has been synthesized and characterized. ... with astressin or its photoactivatable analog thus indicating the specificity of the novel photo ligand. It is noteworthy that the N-terminal amino acid D -Phe in antisauva...

Ngày tải lên: 31/03/2014, 08:20