... changing, roles in the overall patho- genesis of this form of arthritis. In the light of the findings presented by Kim and colleagues [1], it is interesting that a small number of studies have ... disease severity [5]. In another study, EAE failed to resolve in TNFα -/- or TNFR -/- mice, suggesting that TNFα plays an important role in resolution of inflammation [6]. In m...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Anti-inflammatory activity of nanocrystalline silver-derived solutions in porcine contact dermatitis" pptx
... grafts[1-5]. Recently, studies h ave shown that, unlike solutions that contain only Ag + , nanocrystalline silver has anti- inflam- matory activity independent of its antimicrobial activity in a porcine model of ... 20 of 20 - no staining anywhere; 1 - very small areas of staining and/or very light staining; 2 - small areas of dark stain- ing and/or larger areas of lig...
Ngày tải lên: 11/08/2014, 08:22
... S, Shao G, Liu L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. ... pro- tein-binding zinc finger protein 1 (RIZ1). Int J Mol Sci 2008; 9: 943-50. 21. Chen L, Ling B, Alcorn J, Yang J. Analysis of the expression of human N-myristoyltransferase 1 (hNMT-1)...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo Y học: Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein–protein interactions pdf
... Wathelet 1 1 Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati; 2 Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA Virus infection ... reporter in the absence of mCBP, suggesting that IRF-3 by itself is devoid of intrinsic transcriptional activity. Fig. 2. The transcriptional activity of...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Identification of mammalian-type transglutaminase in Physarum polycephalum Evidence from the cDNA sequence and involvement of GTP in the regulation of transamidating activity potx
... might be similar to that by which they inhibit the enzymatic activity of TGase 4. Hydrolysing activity of GTP was also found in the purified PpTGase protein as in the case of TGase 2. Mammalian TGase ... enzymatic activity in the presence of the nucleotides. GTP and ATP clearly inhibited the activity, while GDP showed weak inhibition. GMP did not block the enzymatic activ...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates docx
... those of hK3 and were mainly at P1 Gln residues or b etween residues bearing hydroxyl groups. PAP amidolytic activity was poorly inhibited by all currently used wide spectrum proteinase inhibitors. ... benzamidine, leupeptin, Soya bean t rypsin inhibitor (SBTI) 6,7 ,(1-trans- epoxysuccinyl-leucylamido (4-guanidino) butane (E64 6,7 ), o-phenanthroline, and NaF, w hich inhibits phosphatas...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Bromoperoxidase activity of vanadate-substituted acid phosphatases from Shigella flexneri and Salmonella enterica ser. typhimurium doc
... Software. Assay of PhoN-Se brominating activity. The brominating activity of PhoN-Se was measured by the phenol red assay as mentioned above but using sodium acetate (pH 4.6) instead of citrate. ... easily be detected visually [22]. As phosphate ions inhibit the brominating activity of PhoN-Sf, it is likely that phosphate binds at the active site of the enzyme and prevents bind...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity" pps
... between soluble Cytotoxic T Lymphocyte Antigen- 4 (sCTLA-4) and clinical index of disease activity Bath Ankylosing Spond-ylitis Disease Activity Index in 165 patients with spondylarthropathiesCorrelation ... between soluble Cytotoxic T Lymphocyte Antigen- 4 (sCTLA-4) and clinical index of disease activity Bath Ankylosing Spond- ylitis Disease Activity Index in 165 patients wi...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo" pptx
... consistency in HIV-1 inhibition for >20 experiments. In addition, in this study the cytotoxicity was carefully defined in cell cycle Table 2: WR1065 did not alter cell cycle parameters in HIV-1-uninfected ... not inhibit the antiretroviral activity of AZT. On the contrary, combination of WR1065 with AZT did increase the antiretroviral efficacy of AZT. Anti-SIV activity...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " Differential activity of candidate microbicides against early steps of HIV-1 infection upon complement virus opsonizatio" pdf
... aim of the present proof -of- concept study was to evaluate whether complement opsonization may affect the in vitro activity of a panel of microbicide molecule candidates acting against early steps ... and was maintained in RPMI-1640 containing 10% FCS and anti- biotics (100 μg of streptomycin per ml, and 100 IU of penicillin per ml). Candidate molecules The gp120-interacting...
Ngày tải lên: 10/08/2014, 05:21