Báo cáo y học: "Hepcidin is elevated in mice injected with Mycoplasma arthritidis" ppt

... purposes) Mice injected with M. arthritidis are hypoferremicFigure 2 Mice injected with M. arthritidis are hypoferremic. A. Transferrin saturation was analyzed in C3H/HeJ and C3H/HeSnJ mice injected with ... hepcidin is elevated in mice injected with M. arthritidis. A. Eighteen female mice (10 weeks) C3H/HeJ and 18 female mice (10 weeks) C3H/HeSnJ mice w...

Ngày tải lên: 11/08/2014, 08:22

... tenta- tively supports the hypothesis that a mechanism thorough which abnormal metabolism may ultimately influence ALS pathogenesis is through mechanisms involving reduced expression of Vgf. This evidence ... muscle testing was based on the MRC clinical grading system, out of a total of 100 possible points. ROC analysis was carried out to determine the sensitivity and specificity of Vgf...

Ngày tải lên: 03/11/2012, 10:52

... the binding of DREAM to DNA, which implied a role in the hierar- chical machinery regulating the rat dynorphin-encoding pro- dynorphin (pdyn) gene in a Ca 2+ -dependent manner. Dynorphin interacts ... role in the inherent KOR system previously described in SFLCs [47]. Therefore, DREAM is not a target to locally reduce the intensity of chronic pain in patients with arthritis. Com...

Ngày tải lên: 09/08/2014, 10:23

... protein, also known as CIN85 or SETA, is an adaptor-type protein belonging to the CD2AP/CMS family. It was found in complexes with many signaling proteins, including phos- phoinositol (PtdIns) ... proteolysis, causing an accumulation of proteins that are usually degraded by this pathway [22]. In contrast to lactacystine, which is a highly specific proteasomal inhibitor [23], ALLN inh...

Ngày tải lên: 17/03/2014, 23:20

... employing a nonspecific stimulus. This finding is consistent with the histology found in biopsies of chronic urticaria lesions, where a CD4 + predominant infiltrate is found. 29 Although PMA-I-induced ... antibodies against the eosinophil low-affinity IgE receptor (CD23), which activate eosinophils and induce histamine release by eosinophie cationic protein (ECP), major basic protein...

Ngày tải lên: 08/08/2014, 21:20

... for over-diagnosing polymyositis (PM) [8]; for loosely defining myositis in overlap (overlap myositis [OM]) with another connective tissue disease (CTD) AIM = autoimmune myositis; ALBIA = addressable ... myositis Classification Abbreviation Definition/description Original Bohan and Peter classification PM Primary polymyositis DM Primary dermatomyositis CTM Myositis with another connecti...

Ngày tải lên: 09/08/2014, 10:20

... GMT. Activity and chronicity indices of renal tissue injury Renal tissue injury was evaluated using activity and chronicity indices as previously reported by Austin and colleagues [34]. The activity index ... studies have indicated that aPL may influence the dynamic equilibrium between hemostasis and fibrinolysis by cross-reacting with some hemostatic and fibrinolytic proteases (e.g., plasm...

Ngày tải lên: 09/08/2014, 14:21

... alternative mapping quality ≥35); 2, reads mapping ≥10 kb apart spanned by 1 read pair (with an alternative mapping quality ≥35), with both ends map- ping to within 100 kb of a change point in copy number identified ... genome is show in the outer ring. The blue line indicates changes in copy number as determined by read coverage density. Intra- (green) and inter-chromosomal (purpl...

Ngày tải lên: 09/08/2014, 22:23

... thyroid tumor or other malig nancy. Ectopic thymic tissue can be found along the entire thymic descent path during embryogenesis. However, a thymoma arising from such ectopic thymic tissue is ... microscopy demonstrated the tum or comprised a mixture of lymphocyte-poor spindle cell areas and lymphocyte-rich areas. These histopathologic findings were consistent with a type AB according to...

Ngày tải lên: 10/08/2014, 09:21

... symptoms, making early diagnosis a challenge. We describe here a 42-year- old woman with a primary cardiac osteosarcoma, which was surgically removed by cardiopulmonary bypass. Two years later, ... cavity and their management. Introduction Although osteosarcoma is a common tumor of the skeletal system, primary cardiac osteosarcoma is an extremely rare malignant disease wit h no nspecifi...

Ngày tải lên: 10/08/2014, 09:23