Báo cáo y học: "Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9" pptx

Báo cáo y học: "Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9" pptx

Báo cáo y học: "Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9" pptx

... Access Page 1 of 11 (page number not for citation purposes) Journal of Inflammation Research Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9 Cintia ... cryosections (Fig- ure 3) and intensity of immunoreactivity was measured in the epithelial layer (Figure 2B). CD25 and CD122 immunoreactivi...

Ngày tải lên: 11/08/2014, 08:22

11 242 0
Báo cáo y học: " Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus" pptx

Báo cáo y học: " Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus" pptx

... assays To study the natural T-cell reactivity occurring in unprimed lupus-prone mice, MRL/lpr mice were bled at weeks 8, 10, 12 and 14, and lymphocytes were purified by density separation (Lympholyte-M, ... homogeneity of each purified peptide was checked by analytical high-performance liquid chromatogra- phy (HPLC), and their identity was assessed by matrix- assisted laser deso...

Ngày tải lên: 09/08/2014, 10:21

10 424 0
Báo cáo y học: "Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan" pptx

Báo cáo y học: "Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan" pptx

... Applied Biosystems). Reaction conditions were 50°C for 2 min and 95°C for 10 min, followed by 40 cycles at 95°C for 15 s and 60°C for 1 min. To confirm the quality and accuracy of genotyping data from ... olymorphisms of PLA2R1 and the deve lopment of this disease has not yet been examined. In this study, we analyzed the gene poly- morphisms of PLA2R1 by using TaqMan all...

Ngày tải lên: 10/08/2014, 05:21

8 267 0
Báo cáo y học: "Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study" docx

Báo cáo y học: "Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study" docx

... purposes) Materials and methods This study was approved by the local ethics committee of the Memorial University of Newfoundland and University of Toronto. Informed consent was obtained from all patients. ... the study was 49.7 years. The mean age at onset of psoriasis was 29.3 years (standard deviation 14.2 years) and the mean age at onset of PsA was 38.1 years (standard...

Ngày tải lên: 09/08/2014, 07:20

3 324 0
Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx

Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx

... pathogens and enhance the activ- ity of phagocytes [12]. Homozygosity for variant MBL alleles is probably a minor risk factor for the presence of SLE, as shown by a recent meta- analysis of all ... controls, and functional activity of the MBL pathway was less than 10% of the activity of the standard in 43% of the patients with SLE versus 28% in healthy controls (Table 1)...

Ngày tải lên: 09/08/2014, 08:23

10 325 0
Báo cáo y học: " Identification of functional modules that correlate with phenotypic difference: the influence of network topology" potx

Báo cáo y học: " Identification of functional modules that correlate with phenotypic difference: the influence of network topology" potx

... Addi- tional file 1). The only pathway identified by GSEA and not by PWEA is the Adipocytokine signaling pathway. Poly- morphism of adipokine genes such as LEPR can increase the risk of colorectal cancer ... identified by genetic interactions, phylogeneti c analysis and so on. Here, we define the correlation between genes in a net- work by an influence factor, Ψ.Weconstrainthe...

Ngày tải lên: 09/08/2014, 20:21

16 400 0
Báo cáo y học: " Conservation of functional domains and limited heterogeneity of HIV-1 reverse transcriptase gene following vertical transmission" pdf

Báo cáo y học: " Conservation of functional domains and limited heterogeneity of HIV-1 reverse transcriptase gene following vertical transmission" pdf

... differences observed in the estimates of genetic diversity between and mothers and infants sequences are not statistically significant. Rates of accumulation of nonsynonymous and synonymous substitutions Selection ... transcriptase (RT) enzyme of human immunodeficiency virus type 1 (HIV-1) plays a crucial role in the life cycle of the virus by converting the single stranded...

Ngày tải lên: 13/08/2014, 09:21

17 252 0
Báo cáo y học: "Comparison of functional residual capacity and static compliance of the respiratory system during a positive end-expiratory pressure (PEEP) ramp procedure in an experimental model of acute respiratory distress syndrome" potx

Báo cáo y học: "Comparison of functional residual capacity and static compliance of the respiratory system during a positive end-expiratory pressure (PEEP) ramp procedure in an experimental model of acute respiratory distress syndrome" potx

... sequential ramp change of PEEP from 20 cm H 2 O to 0 cm H 2 O by steps of 5 cm H 2 O, the end of overdistension may be identified by an increase in Crs, and the start of derecruitment by an abrupt decrease ... inspiratory plateau airway pressure (Pins) and a 10 s expiratory pause to obtain the end-expiratory airway pressure (Pexp). The value of Crs was obtained by divi...

Ngày tải lên: 13/08/2014, 11:22

6 275 0
Báo cáo y học: "Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences" pps

Báo cáo y học: "Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences" pps

... very widely used, because the normalization by Ks yields a metric of amino acid selection pressure that is independent of π (which varies enormously according to the total time of evolutionary divergence ... alternatively spliced exon. Comparisons of these four genomes consistently show an increase in the density of amino acid mutations (Ka) in alternatively spliced exons, and a...

Ngày tải lên: 14/08/2014, 14:21

30 131 0
Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"

Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"

... fibrosis), and S4 (cirrhosis), and grade of disease activity was defined as G0 (no activity), G1 (mild activity), G2 (moderate activity), and G3 (severe activity). All the sections were blindly and ... Body mass index (BMI) BMI was calculated as the individual's body weight divided by the square of his or her height. According to the new BMI criteria for Asians by th...

Ngày tải lên: 25/10/2012, 11:48

6 606 0
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