Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot
Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot
... that PIN1 may normally function to maintain calpain activity and, consequently, restrain the induction COX-2, iNOS, and perhaps other substrates in MAEC. PIN1 is likely to regulate a range of calpain- dependent ... slowed the degradation of COX-2 in MAEC, an effect recapitulated by an inhibitor of calpain. Given the sensitivity of COX-2 and iNOS to calpain, P...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: "Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)" pps
... 126:81-84. 105. Yoshie O, Fujisawa R, Nakayama T, Harasawa H, Tago H, Izawa D, Hieshima K, Tatsumi Y, Matsushima K, Hasegawa H, Kanamaru A, Kamihira S, Yamada Y: Frequent expression of CCR4 in adult T- cell ... I tax. Int J Cancer 2005. 24. Yamaoka S, Inoue H, Sakurai M, Sugiyama T, Hazama M, Yamada T, Hatanaka M: Constitutive activation of NF-kappa B is essential for transformation...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor κB-dependent pathway in patients with rheumatoid arthritis" ppt
... ACC TGG AAA TAC CCA AAA TTC-3') were generated by 5'- end labeling of the sense strand with [γ- 32 P]dATP (Amer- sham Pharmacia) and T4 polynucleotide kinase (TaKaRa). Unincorporated nucleotides ... proinflam- matory properties [5,22]. RA is characterized by hyperpla- sia of synovial lining cells and an intense infiltration by mononuclear cells [23]. Proinflammatory cytoki...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Dynamic compression counteracts IL-1β induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs" pdf
... and revealed efficiency values presented in table 1. Data normalization and statistical analyses Fluorescence data was collected during the annealing stage of amplification and data was analyzed ... pairs) Efficiency iNOS U14640 Probe: 5'-FAM-CGCGATCCCTGCTTGGTGGCGAAGATGAGCGATCGCG-DABCYL- 3' Forward: 5'-GTAACAAAGGAGATAGAAACAACAGG-3' Reverse: 5'- CAGCTCCGGGC...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line" pptx
... protein-protein interaction and catalytic activity of the PARP protein play a key role in modulation of the heat shock response. Acknowledgements Funding for this study was provided by the National Institutes ... Salzman AL, Szabo C: Peroxynitrite- mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: " Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line." pptx
... Veres B, Gallyas F Jr, Varbiro G, et al: Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly- (ADP-ribose) polymerase 1 inhibitor in endotoxin-induced ... conceived the study. RA, RLD participated in the design of the study. All authors read and approved the final manuscript. Competing interests The authors declare that t...
Ngày tải lên: 11/08/2014, 06:22
Báo cáo y học: " Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics" docx
... A, Sumida Y, Gabazza EC, Murashima S, Morioka K, Maruyama N, Kitagawa N, Tanaka T, Hori Y, Nakatani K, Yano Y, Adachi Y: Oxidative stress is associated with adiposity and Respiratory Research 2007, ... airway changes in airway NO and airway oxidative stress. Overall, these find- Association of the ratio of serum leptin and serum adiponectin with the log of exhaled NO...
Ngày tải lên: 12/08/2014, 15:20
Báo cáo y học: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment" pot
... 1Y6 , Canada, 2 Second Department of Internal medicine, Nagasaki University School of Medicine, Nagasaki, Japan and 3 Environmental Health Directorate, Health Canada, Ottawa, Ontario, Canada Email: ... PM 10 (EHC-93)-induced interaction of human AM and bronchial epithelial cells (HBEC) enhances the synthesis and release of a variety of pro- inflammatory cytokines and...
Ngày tải lên: 12/08/2014, 18:22
Báo cáo y học: "SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques" pptx
... GuidefortheCareandUseof Laboratory Animals” prepared by the National Research Council. The studies were approved by the University of Pennsylvania and Tulane Institutional Animal Care and Use ... 3, 5, and 7) and la te (days 9, 1 1, and 14) time points as groups. Comparing viral replication in all animals induced by gag and pp65 immunization in draining LNMCs at t he e...
Ngày tải lên: 13/08/2014, 01:21
Báo cáo y học: " Formulas Pro/con debate: Is intensive insulin therapy targeting tight blood glucose control of benefit in critically ill patient" doc
... [21,23], although some of the trials have been small [21]. As in many areas of intensive care practice, the choice of a target range for blood glucose is a matter of balancing potential benefit against ... morbidity and mortality as well as the characteristics of the individual ICU, such as availability of staff and laboratory equipment [39]. Until the balance...
Ngày tải lên: 13/08/2014, 08:21