Báo cáo y học: "Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis" pdf
Báo cáo y học: "Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis" pdf
... against nitric oxide-induced death via cGMP signaling pathway. Br J Pharmacol 2003, 139:28-34. 25. Yoshioka Y, Yamamuro A, Maeda S: Nitric oxide/cGMP signaling pathway protects RAW264 cells against ... E: Quantification of peroxyni- trite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperi- dine. Biochem Biophys Res Commun 1997,...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: " Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro" ppsx
... pathology was the presence of bron- chial epithelial cell hypertrophy. The hypertrophic cells extended into the secondary and tertiary airways. Epithe- lial cell hypertrophy is normally associated ... double-stranded (ds) RNA as well as the synthetic ds RNA analog poly- riboinosinic-ribocytidylic acid (poly(I:C)) [1]. Activation of TLR3 by poly(I:C) or by endogenous mRNA ligands, such as thos...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: " Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro" pptx
... Cyclic hydro- static pressure and UHMWPE particles modulate synthesis of 1,25-dihydroxyvitamin D 3 by human peripheral blood monocytes. International Journal Biochemistry & Cell Biology ... physical forces on alveolar macrophages is a physiologically relevant issue, but as yet understudied. This study examines the effect of cyclic hydrostatic pressure and cotton particles on synthesi...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt
... broad speci®city w ith respect to the g lycone moiety of substrates. Human CBG hydrolyses synthetic aryl glycosides (including 4-nitrophenyl and 4-methylumbelliferyl monoglycosides) [9], but no physiological ... [the hydrolysis of 4NP-b- D - glucopyranoside (10 m M ) was reduced by 98% in the presence of 4NP-b- D -mannopyranoside (10 m M )]. Hydrolysis of xenobiotic glycosides by reCBG The...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway pot
... the hydrolysis of substrate by water, by heating the enzyme at 70 °C for 15 min prior to the assay. The enzyme reactions carried out with heated Fig. 1. Sequence alignment of human and yeast ... colorimetric assay in a 96-well format was also developed using p-nitrophenyl-thymidine-3¢-phos- phate as substrate. This assay system is able to detect enzy- matic activity at enzyme concentrations...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases" pot
... low-intensity fractions by cell sorting, and they found that the suppressive effects were only displayed by the high-intensity fraction [17]. This subset did not produce cytokines. Cytokine-dependent ... inhibitory effects on lympho- cyte cytokine production and functional properties [35], our laboratory has accumulated data that these effects can be overcome by IL-2 and can be superceded by...
Ngày tải lên: 09/08/2014, 03:24
Báo cáo y học: "Anti-Sa antibodies and antibodies against cyclic citrullinated peptide are not equivalent as predictors of severe outcomes in patients with recent-onset polyarthritis" pdf
... B, Calin A, the European Spondylarthropathy Study Group: The European Spondylarthropathy study Group preliminary criteria for clas- sification of spondylarthropathy. Arthritis Rheum 1991, 34:1218-1227. 35. ... Silman A, Symmons D: Disability in patients with early inflammatory polyarthritis cannot be 'tracked' from year to year: an examination of the hypothesis underlying percentile...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Polarized subsets of human T-helper cells induce distinct patterns of chemokine production by normal and systemic sclerosis dermal fibroblasts" doc
... induced by Th1 cells was not significantly affected by any of the inhibitors used, but the MCP-1 levels induced by Th2 cells were affected strongly by both U-0126 and PSI and weakly by the JNK ... IL-8 was not induced by any of the Th1 and Th2 cytokines, but was strongly induced by Th2 and to a lesser extent by Th1 cells – an effect due to cytokines (IL-1 and TNF-α) shared by the two T cell ....
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts" doc
... inflam- matory conditions where they produce larger amounts of inflammatory cytokines. At present, it is not clear whether mouse monocyte subsets, Ly-6C low /Ly-6C high , represent human monocyte subsets, ... 5 Flow cytometric analysis of ERK1/2 and p38 MAPK phosphorylation on monocyte subsetsFlow cytometric analysis of ERK1/2 and p38 MAPK phosphorylation on monocyte subsets. Purified monoc...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats" ppt
... activity were used, and joint swelling in both ankles was measured every 3 to 4 days by plethysmometry (TK101CMP; Muromachi-kikai, Tokyo, Japan). Arthritis score was measured every 3 to 4 days by ... Phagocytosing activity was detected by phagocytes of fluoresbrite YG microspheres ® (Poly Sciences, Inc., Warrington, PA, USA). IL-17 and IFN-γ measurement from human T cells stimulated by IL...
Ngày tải lên: 09/08/2014, 10:21