Báo cáo y học: "Inhibition of zymosan-induced kidney dysfunction by tyrphostin AG-490 " pot
Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt
... permeability studies The effect of 2-APB on membrane permeability was monitored by assessing the quenching of calcein dye trapped in egg phosphatidylcholine liposomes by Co 2+ , as described by Longland ... quite dramatically in the presence of 2-APB (by nearly eightfold). In addition, the rate constant for Ca 2+ dissociation in the presence of 2-APB is also substantially incre...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Inhibition of allogeneic inflammatory responses by the Ribonucleotide Reductase Inhibitors, Didox and Trimidox" pot
... benefit. More recently, the immune modulatory effects of HU have been postulated. Lori et al described the “predator- prey” hypothesis [29] where the cytostatic effects of HU would force T-lymphocytes into ... oroakl1@uky.edu 1 Department of Clinical Sciences, University of Kentucky, Lexington, KY 40536, USA Full list of author information is available at the end of the article In...
Ngày tải lên: 11/08/2014, 06:22
Báo cáo y học: " Inhibition of lung serine proteases in mice: a potentially new approach to control influenza infection" doc
... Activation of influenza A viruses by trypsin treatment. Virology 1975, 68:426-439. 6. Lazarowitz SG, Choppin PW: Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of ... autoca- talytically [16,17]. The catalytic domains of the TMPRSS were thought to be only linked to the membrane-bound N-terminal chain of the enzyme by a disulfide bridge; h...
Ngày tải lên: 11/08/2014, 21:21
Báo cáo y học: " Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression" potx
... triplicate. Gene expression analysis by microarrays The microarray analysis of the effect of GliPR suppres- sion by siRNA was performed using the HG-U133 Plus 2.0 microarray of Affymetrix (Santa Clara, ... up-regulation of GliPR by HIV-1 and the early significant inhibition of HIV-1 replication mediated by knockdown of GliPR reveal GliPR as an important HIV-1 dependency fa...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo y học: "Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex" potx
... Wendy Maury* 1,2 Address: 1 Interdisciplinary Molecular and Cellular Biology Program, University of Iowa, Iowa City, IA, USA, 2 Department of Microbiology, University of Iowa, Iowa City, IA, ... form contains Cdk9 and one of several cyclin regulatory subu- nits, cyclin T1, cyclin T2a, cyclin T2b or cyclin K, with cyc- lin T1 being the predominantly associated cyclin in many cell ty...
Ngày tải lên: 13/08/2014, 05:22
Báo cáo y học: "Inhibition of zymosan-induced kidney dysfunction by tyrphostin AG-490." pot
... be constitutively expressed on human and mouse kidneys and TLR2 deficiency protects from the renal ischemia- Effect of AG-490 on kidney dysfunction induced by zymosanFigure 2 Effect of AG-490 on kidney dysfunction ... citation purposes) Journal of Inflammation Open Access Research Inhibition of zymosan-induced kidney dysfunction by tyrphostin AG-490 Petya Dim...
Ngày tải lên: 11/08/2014, 08:22
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... the primary hereditary cardiomyopathy of the Syrian hamster. I. Regulation of prodynorphin gene expression by nuclear protein kinase C. J. Biol. Chem. 272, 6685–6692. 22. Ishizuka, S., Yano, T., ... Such a hypo- thesis is further confirmed by the observation that, differ- ently from the effect of serum, the stimulatory effect of PMA on ERK1/2 activity could also be totally abolishe...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity introduced by the substitution, as is often the case in ribozyme inhibition by tetracyclines [33,39,43]. In ... of chlorine for hydrogen at position 7 (Fig. 1C). Inhibition by Cl-tetracycline w as found to be sixfold more t han by tetracycline (Fig. 2). The extent of splicin...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... Laemmli [32]. Assay of cell-free HA synthesis Cell-free HA synthesis was performed by a modification of the method reported by Nakamura et al. [18]. Analysis of the transfer of UDP-[U- 14 C] GlcUA ... treatment may cause a decrease in hyaluronan synthase activity by altering the lipid environment of membranes, especially the distribution of different cardiolipin species, surro...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... inhibition of platelet aggregation [6,7] and inhibition of inflammatory cytokine production in macrophages [8]. Curcumin has also been shown to affect the activity of a number of key enzymes such as cyclooxygenase ... fluorescence intensity represents quenching of the fluorescent dye by Co 2þ ions. Upon addition of curcumin, the rate of quenching is substantially increased and de...
Ngày tải lên: 08/03/2014, 23:20