Báo cáo y học: " Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis" pptx
Báo cáo y học: " Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis" pptx
... CentralPage 1 of 12(page number not for citation purposes)Journal of InflammationOpen AccessResearch Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced ... inflammatory histopathology of CIAFigure 5 Anti-IL-6 antibody reduced the inflammatory histopathology of CIA. DBA/1 LacJ mice were dosed with irrelevant control antibody (A) or anti-IL-6 antibody (1 ... influence of IL-6 inarthritis, by examining the effects of anti-IL-6 mAb treat-ment in a murine model of type II collagen induced arthri-tis (CIA).MethodsInduction and Assessment of Type II Collagen-induced...
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Báo cáo y học: "Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis" pptx
... replacement therapy and eight had subclinical hypothyroidism (thyrotropin>4 µIU/ml and normal thyroxine levels) [27], none had clinicalhypothyroidism (decreased thyroxine levels) at the time of thestudy. ... roleplayed by an extensive range of patient characteristics inendothelial dysfunction. Finally, we assessed the associationbetween biomarkers of endothelial dysfunction and ultrasono-graphically ... employed to assess endothelialfunction. Using ultrasonographically measured brachial arteryflow mediated dilatation or vasodilatory responses to intrabra-chial artery infusion of acetylcholine,...
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Báo cáo y học: "Elimination of rheumatoid synovium in situ using a Fas ligand ''''gene scalpel" pptx
... molecular synovectomy procedure. In theory, inflammatorysynoviocytes in implanted RA synovium in SCID mice mayconsist of antigen specific human lymphocytes, proliferatedhuman fibroblast-like synoviocytes, ... of Pharmaceutics and Industry Pharmacy, School of Pharmacy, Long Island University, Brooklyn, NY, USA2Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA, ... vector can infect awide variety of cell types in human synovium including synovi-ocytes, lymphocytes, macrophages, granulocytes andendothelial cells, as determined by X-gal staining (Fig. 1g–k).In...
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Báo cáo y học: "Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis" pptx
... developedby Clayton [12]. All the results were produced using STATAsoftware (David Clayton, Cambridge, UK).In case of replication of the genotype risk hierarchy, a homo-geneity test on genotypic ... S3P/L genotypes, with ORs of 8.7, 5.3 and 3.1,respectively (with the reference genotype being L/L; Table 2).This hierarchy was precisely the same as observed previously[6].Results of the homogeneity ... reference genotype is L/L. aPseudo-controls are the three other genotypes that could be formed by the parental genotypes.Arthritis Research & Therapy Vol 8 No 3 Michou et al.Page 6 of 6(page...
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Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"
... 5. de Godoy JM, de Godoy Mde F. Physiopathological hypothesis of cellulite. Open Cardiovasc Med J. 2009;31(3):96-7. 6. Godoy JMP, Almeida EMMZNM, Silva SH, Godoy MFG. Pilot study of the intensive ... Grade II and III cellulite. All patients treated for Grade II and III cellulite were evaluated for idiopathic cyclic edema in a retrospective, quantitative and cross-sectional study. The study ... Lipoedema of the legs. A syn-drome characterized by fat legs and edema. Ann Intern Med. 1951 May;34(5):1243-50. 9. Pereira de Godoy JM. Aminaphtone in idiopathic cyclic oedema syndrome. Phlebology...
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Báo cáo y học: " Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-U"
... al. Efficacy and validity of radiofrequency neurotomy for chronic lumbar zygapophysial joint pain. Spine (Phila Pa 1976). 2000; 25: 1270-7. 32. Merskey H, Bogduk N. Lumbar zygapophysial joint ... unless the same methodology is used for both diagnosis and therapy. The generalizability of the findings of this study might only be feasible if studies are published using large populations ... Level II- 2 evidence for lumbar radiofrequency neu-rotomy.29-31 The exact mechanism of the therapeutic effect of lumbar facet joint nerve blocks is not known, whereas radiofrequency neurotomy...
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Báo cáo y học: "Evaluation of maternal infusion therapy during pregnancy for fetal development"
... termination of pregnancy were selected. This shorter time between “pregnancy end” and data collection increases the accuracy of information about pregnancy history without undue loss of power ... (iii) the fourth to ninth months of gestation. If pregnant women had infusion twice or more during the study pregnancy, only one treatment was analysed according to the following priority: ... infusion in the second month of gestation, i.e. during the critical period of renal a/dysgenesis. The type of drugs obviously has a greater impact for fetuses than the route of administration [17]....
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Báo cáo y học: "Evaluation of Fractional Analysis of Bronchoalveolar Lavage Combined with Cellular Morphological Features"
... Morphology of hypersensitivity pneumonitis (HP) lymphocytes. HP lymphocytes morphology and diameter varied considerably. The cell morphology was consistent with activated -type lymphocyte. They presented ... FBAL-III respectively (Figure 2). The mean lympho-cyte percentage of patients who had lung involve-ment (stage II or III) did not differ in clinical symp-toms and laboratory data from those of ... FBAL-III. Mφ: macrophages, Ly: lymphocytes, Neu: neutrophils, Eo: eosi-nophils Patients’ group showing the highest rate of lympho-cytes. Of the 2260 patients, 488 (21.6%) showed a lymphocyte...
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Báo cáo Y học: Evaluation of two biosynthetic pathways to d-aminolevulinic acid in Euglena gracilis potx
... entry of [2-13C]acetyl CoA ( 8ii) into the TCA cycle, and (C) is13C-carbon from the third entry of [2-13C]acetyl CoA (8iii)intotheTCAcycle.13C-Labeledpositions of succinyl CoA (cccc) ( 5ii ... C-P16) of the phytyl moiety of 13C-labeled chlorophyll a were higher than those of carbons of the chlorin ring moiety.Synthesis of 13C-labeled methyl pheophorbideaand determination of 13C-incorporation ... ratio(1.8-fold) of the methoxyl carbon of the methoxycarbonylgroup at C-132 of 13C-labeled methyl pheophorbide a.During the exchange of the phytyl ester to the m ethylester i n the transformation of 13C-labeled...
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Báo cáo y học: ":Evaluation of the Patient Acceptable Symptom State in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis" pptx
... canbe adequately performed not only by using a conventionalapproach (for example, by comparing changes in conventionaloutcome variables by treatment group during the study) butalso by referring ... 5).Achievement of sustained PASS during the studyAchievement of a sustained satisfactory symptom stateaccording to PASS, maintained from the clinic visit during thestudy until the end of the study, is ... the novel concept of PASS.The statistical analysis of continuous variables is usually con-sidered as more powerful than the analysis of dichotomousvariables. The concept of PASS does necessitate...
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