Báo cáo y học: " Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively" docx
Báo cáo y học: " Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively" docx
... Inflammation Open AccessResearch Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively?Giovanni Tarantino*1, ... postulated to exists in humans [14]. The aim of this study was to ascertain j) the differences, ifany, between young obese individuals with such anapparently harmless phenotype without IR and young obese ... Metabolic syndrome was much more frequent in obese patients with insulin resistance. These findings show that in young adults the only abdominal adiposity without insulin resistance, plays a scarcerole...
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Báo cáo y học: "XeNA: Capecitabine Plus Docetaxel, With or Without Trastuzumab, as Preoperative Therapy for Early Breast Cancer" pps
... treated with HXT, the pCR rate was 45%. HXT dem-onstrated good tolerability in these studies: the lower XT dose is well tolerated, and HXT may reduce the risk of overlapping cardiac toxicity with ... factor receptor 2 (HER2)-positive breast cancer, as they offer less cardiotoxicity and thus can be used concomitantly with preoperative trastuzumab therapy. Capecitabine plus docetaxel (XT) and ... Monitoring Board evaluated the safety and initial ef-ficacy after treatment of a predetermined number of patients. Based on their analysis of the data, the trial was allowed to continue with...
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Báo cáo y học: "Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease" pdf
... usually otherwise healthy patients with pure food restriction, normal serum albumin levelsfrequently mask the severity of their serious m edicalcondition [6,7]. A recent analysis of patients with ... components of the com-plement cascade and a nalyzed the activities of the alter-native complement activation pathways [24]. Serumlevels of C3, Factor B and D, hemolytic activity of the alternative ... innate immunity, represents a drivingforce in the pathophysiology of multiple inflammatory disorders. The role of complement in anorexia nervosaremains poorly understood. The present study was designed...
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Báo cáo y học: "Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature" pptx
... imageacquisition, and to H.J. Buikema for assistance with histopathological imageacquisition. This study was financially supported by University MedicalCenter Groningen and the Groningen University ... originallyin July 2003. M anifestations of his disease includedarthritis, pericarditis, and pleuritis without any evidence of skin, cerebral o r renal involvement. Laboratory find-ings are shown ... endocarditis and intracardiac tumorsDue to its asymptomatic nature establishing a diagnosis of LS endocar ditis can be rather difficult. This is furthercomplicated by the fact that the condition...
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Báo cáo y học: " Biliary peritonitis caused by a leaking T-tube fistula disconnected at the point of contact with the anterior abdominal wall: a case report" docx
... and Emergency department with a 7-hourhistory of vomiting and central abdominal pain radiating to the back. There were no respiratory, cardiovascular orurinary symptoms, and past medical history ... biliary peritonitis. T-tube insertion is performed to reduce the risk of this occurringpostoperatively. Biliary leakage at the point of insertion into the common bile duct, or along the fistula, ... by dehiscence of a fistula tract at itscontact point with the anterior abdominal wall. Hepato-biliary surgeons should be aware of this mechanism of biliary leakage and the use of laparoscopy...
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Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf
... from 30 patients with SLE and 30patients with RA were obtained from the University of Washington (Seattle, WA, USA) serum repository. Dr.Dall’Era and Dr. Wofsy from the University of Califor-nia, ... levels and other markers of SLE disease activity. The 36 samples from patients with Figure 4 (a) Biologic activity and (b) neutralization of BLyS/APRIL HTs compared with those of BLyS and APRIL ... butexhibited little or no inhibition of heterotrimer orAPRIL activity. This was expected and consistent with the observed binding of BLyS, but not APRIL, to BAFF-R. It could be hypothesized that the...
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Báo cáo y học: "In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype" pdf
... carried out the sero-logical typing. NS assisted with the statistical analysis. BTassisted with the genotyping. WT assisted with the genotyp-ing and contributed to preparation of the manuscript. ... and DM. However, due to very strong LDshared within the haplotype, and the limited examination of the region to date in IIMs, it is currently difficult to speculate furtherabout the precise location ... myositis patients with differing myositisserology have different immunogenetic profiles, and that theseprofiles may define specific myositis subtypes.Introduction The idiopathic inflammatory...
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Báo cáo y học: " An adult case of urinary tract infection with Kingella kingae: a case report" doc
... positive) and positive for the Penicillin Gdisc test. Of all of the species, K. kingae is b-hemolytic onsheep blood agar [2]. The isolation of K. kingae is ofteneither missed or misinterpreted. ... positivity, catalase negativity and positive penicillin G disc test.DiscussionK. kingae, though a part of the normal upper respiratorytract and genitourinary tract, is increasingly being recog-nized ... hygiene, pharyngitis and mucosal ulceration are the predisposing factors for K. kingae infections [2,3].K. kingae bacteremia without endocarditis has also beenreported in immunocompetent adults...
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Báo cáo y học: "Hypocellular acute myeloid leukemia with bone marrow necrosis in young patients: two case report" ppsx
... evaluated in either patient due to unavailability of the facility in the department.Discussion The occurrence of hypoplastic acute leukemia is widelyrecognized as an atypical leukemia, and is defined ... [11]. Alternatively, an increased sus-ceptibility of myeloid precursors to the inhibitor in olderpatients might play a role in the genesis of hypoplasia [8].However, the cause of hypoplasia in ... commonly achievea good response to remission induction therapy. This dis-ease has a proclivity for older patients, however, we found it in young patients. Although the majority of hypocellu-lar...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... could dis-tinguish CRC from healthy controls with the sensitivity of 92.85% and the specificity of 91.25%. Blind test data indicated a sensitivity of 86.95% and a specificity of 85%. The result ... immunologic and biochemistry test. But, the sensitiv-ity and specificity of the current biomarkers in tumor diagnosis is low (usually less than 70%) and compli-cated by high return of ‘false-positives’ ... for the diagnosis of CRC, the intensities of the protein peaks in the training set were submitted to BPS. A total of four peaks (2870.7, 3084, 9180.5, 13748.8) with the highest discriminatory...
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