Báo cáo y học: "Anti-inflammatory effects of the gorgonian Pseudopterogorgia elisabethae collected at the Islands of Providencia and San Andrés (SW Caribbean)" potx
Báo cáo y học: "Anti-inflammatory effects of the gorgonian Pseudopterogorgia elisabethae collected at the Islands of Providencia and San Andrés (SW Caribbean)" potx
... activity of extracts and fractions, and invitro anti-inflammatory activity of pure compounds, all isolated from Pseudopterogorgia elisabethae collected at the Providencia (chemotype 1) and San Andrés ... of 10(page number not for citation purposes)Journal of InflammationOpen AccessResearchAnti-inflammatory effects of the gorgonian Pseudopterogorgia elisabethae collected at the Islands of ... elisabethae collected at the Providencia and San Andrés Islands (SW Caribbean) [16,17]. The extracts and fractions from the two chemotypes were assayed using the in vivo model "12-O-tetradecanoyl-phorbol-acetate...
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Báo cáo y học: "Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation" pps
... lining and the joint cavity, by 30% to 60% at day 3 after the onset of ICA.Despite the enhanced inflammatory response, chondrocytedeath was diminished by two-thirds at days 3 and 7. The mRNAlevel ... with hematoxylin. Macrophage and PMNsubsets were quantitatively measured using an image anal-ysis system. The inflammatory cell mass was selected byhand and the amount of positive features ... manuscript. TR participated in the preparation of the manuscript. WB participated in the design of the study and preparation of the manuscript. Allauthors read and approved the final manuscript.AcknowledgementsSupported...
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Báo cáo y học: "Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13" docx
... GBG and CB participated in the study design.CB, JC and JPP participated in the acquisition of data. CB, JM-P, JC and JPP participated in the analysis and interpretation of data. CB, JM-P and ... chondrocytespreviously published by Henrotin and coworkers [54]. The present study has limitations largely imposed by the studydesign. One such limitation is the duration of the study (8weeks). ... effect of ASU on clinical symptoms of knee and hip OA, with a carry-over effect that persists after termination of treatment [10-12]. The primary aim of the present study was to explore the effects of...
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Báo cáo y học: "Toxic effects of methoxychlor on the episodic prolactin secretory pattern: Possible mediated effects of nitric oxide production" pdf
... terms of NIADDrat PRL-RP3 reference preparation. The sensitivity of the assay was 5 pg/tube. To analyze the variability of the assay, series of plasma of 10 replicates at 4 different con-centrations ... duration was the timebetween the beginning of the ascending phase of the peak and the end of the descending phase of the peak. The mean hormone level was calculated by the mean of allsamples collected ... Blockade of NO synthesis by the administration of Nω-nitro-L-arginine methyl ester (L-NAME), inhibits the preovulatory peak of prolactin [25]or attenuates the inhibitory effect of dopamine...
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Báo cáo y học: "Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver" ppt
... inflammatory mediators includ-ing activity and expression of cyclooxygenase (COX)[4,5], generation of prostaglandins [6,7], and leukotrienes(LT) [4] and expression of proinflammatory cytokines[5,8]. ... mechanismsby which parthenolide imparts its effects on inflammatoryresponses.Investigations of the anti-inflammatory properties of par-thenolide, and feverfew have focused on suppression of primary ... reportedly reduced by parthenolide treat-ment, there are limited data evaluating the effect of par-thenolide on mRNA expression of these cytokines. Hwanget al. [5] showed that parthenolide...
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Báo cáo y học: " Understanding effects of armed conflict on health outcomes: the case of Nepal" pptx
... regions of Nepal [27]. The methods and tools of this study does not seem compatible to the NFHS 1996 and NDHS 2006. Moreover, th e sample size of the NHRC study is relatively small. The results of the NHRC ... spec-tively. In case of MDG 4, the infant and child mortalityrates have dropped by 31% and 57% respectively and the coverage of childhood vaccines (intermediate indicators)increased over the years. ... 2015.DiscussionFrom the point of view of the impact of the conflict, the data available from the two DHSs suggest more of apositive than of a negative impact on the health out-comes. The comparative data on...
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Báo cáo y học: "Positioning Effects of KillerRed inside of Cells correlate with DNA Strand Breaks after Activation with Visible Light"
... lo-calization and their resulting effects as discussed by Waldeck [17]. Therefore the rationale of this manuscript is the estimation of the cell toxicity by measurements of DNA-strand breaks ... 2D). The yellow-fluorescence signals are perinu-clearly located and are caused by the merged red fluorescence of the KRED and the green fluores-cence of the ATTO 633 (Figure 2D). The extreme ... sensitivity of the DNA against damaging processes is documented [28-30]. Here we also investigated the question of the dependency of the spatial proximity of the ROS producing KRED protein to the...
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Tài liệu Báo cáo Y học: Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils pot
... showingthat AA constitutes the bulk of the fatty acid at the sn-2position of 1-alkyl-2-acyl-GPC under resting conditions[70]. Upon cell activation, most of this AA is replaced byother fatty acids. ... that favor AA-CoA synthetase and CoA-acyl transferase activities arerequired to fully identify the role of these enzymes in lipidmediator formation.Overall, these data highlight the role of ... resulting in the formation of 1-alk-1-enyl-2-lyso-GPE. Wykle and colleagues haveshown that 1-alk-1-enyl-2-lyso-GPE enhances PAF for-mation by a CoA-IT-dependent generation of lyso PAF[55].Thus,whilePLA2isotypes...
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Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
... GST– cyto -Y6 41F (Y! F mutation at the 641 position), GST– cyto -Y6 67F (Y !F mutation at the 667position), GST– cyto -Y6 91F (Y! F mutation at the 691position), and GST alone proteins were coated on ... siglec tail by Lck and Jak3 kinases. Bycomparison, the mutation of the tyrosine at position 641 didnot significantly affect the degree of phosphorylation by any of the kinases that were tested. ... inflammatory cells at sites of inflammation,we searched the Incyte EST database and found thatFig. 7. Phosphatases SHP-1 and SHP-2 in celllysates bind to a GST fusion of the cytoplasmicdomain of...
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