Báo cáo y học: "Upregulation of prolylcarboxypeptidase (PRCP) in lipopolysaccharide (LPS) treated endothelium promotes inflammation" pot
Báo cáo y học: "Upregulation of prolylcarboxypeptidase (PRCP) in lipopolysaccharide (LPS) treated endothelium promotes inflammation" pot
... define the inflammatory properties of
HUVECs, a panel of nine biomarkers of activated
endothelium participating in thrombophilia, fibrinolysis,
endothelial viability, and inflammation was analyzed ... inflammatory insult.
This amplification may be an additional mechanism
whereby PRCP promotes a sustained inflammatory
response. Of note, PRCP has the ability to metabolize des-
Arg...
Báo cáo y học: "Role of Genetic Polymorphisms in Therapeutic Response to Anti-Asthma Therapy" pot
... aid in choosing the most appropriate therapy. As
clinicians attempting to stay current in the evolving science
of asthma, we must continue to follow the very exciting
literature regarding potential ... with examining genetic poly-
morphisms (GPs) may seem like bringing meaning to
alphabet soup, it is quite likely that further advancement in
our understanding of genetics will provide...
Báo cáo y học: " Upregulation of Bax and Bcl-2 following prenatal cocaine exposure induces apoptosis in fetal rat brain" doc
... cocaine 60 mg/kg/day. Cocaine HCl was dissolved
in saline at 10 mg/ml and injected subcutaneously into
the pregnant rats at ~10:00 A.M. once a day, starting at
day 15 of gestation. Saline-injected ... temporal profile of bcl-2 and bax
gene products in terms of protein expression in the
fetal brain after cocaine exposure. The current findings
that cocaine significantly increas...
Báo cáo y học: "Upregulation of a novel eukaryotic translation initiation factor 5A (eIF5A) in dengue 2 virus-infected mosquito cells" pot
... of lysine by spermidine [14].
The eIF5A protein was originally considered to be a
translation initiation factor based on its in vitro activity of
stimulating the formation of methionyl-puromycin, ... molecular
mass of 17~21 kDa, and is relatively conserved from
yeast to humans [13]. It is the only protein in nature
known to contain the unusual amino acid, hypusi ne
[N
ε
-(4-amino-...
Báo cáo y học: " Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis" ppsx
... microar-
rays of phenotypically normal individuals that smoke
[24], a finding also made by Spira et al [37], in their study
of genes up-regulated in the airway epithelium of smok-
ers. Interestingly, Spira ... dramatically
increased. In the cyanobacterium Synechocystis, pirin
orthologs are highly induced under conditions of severe
salt stress [28].
We originally noted pirin to b...
Báo cáo y học: "Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients" pps
... have been described in
a recent study investigating the potential of the mea-
surement of Annexin-V binding on lymphocytes as a
biomarker in emergency departments [17].
Regarding mRNA experiments, ... at days 1 to 2
and at days 3 to 5 after diagnosis of shock. Circulating leukocyte immunophenotyping was systematically performed by flow cytometry. The following leukocyte
subsets were...
Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"
... with clinically and pathologically proven steatosis
and 98 patients without steatosis were recruited into this study. The levels of fasting blood
glucose (FBG), fasting insulin (FINS), triglyceride ... levels
of serum alanine aminotransferase (ALT). The higher
prevalence of hepatic steatosis in Hispanics was
mainly due to the higher prevalence of obesity and
insulin resistance...
Báo cáo y học: "Management of HBV Infection in Liver Transplantation Patients"
... absence of detectable HBV DNA at the time of OLT and absence of
reinfection for a minimum of 6 months post-OLT. After one year, reinfection occurred in 20% of patients in each group, but the
finding ...
finding of circulating HBV DNA by PCR in 2 of 11 receiving HBIG and 5 of 10 receiving LAM suggests that reinfection would be
likely in additional patients with long...
Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... level of the has
operon containing the hyaluronan synthase gene or the
protein level of hyaluronan synthase. Solubilization of the
enzyme from membranes of MU -treated cells and addition
of the ... little involvement of MU-meta-
bolites in the inhibition of HA synthesis by MU in FM100
cells. These above results indicate that something required
for a fully functional HA synt...
Báo cáo Y học: Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase A site-directed mutagenesis study docx
... half-reaction of Y2 38 mutants with
D
-alanine
was measured by mixing anaerobically a solution of each
mutant enzyme with solutions containing varying concen-
trations of
D
-alanine, such that ... depending on the
size of the ligand side chain [27]. Our results indicate that
the role of Y2 23 and Y2 38 in the active site of RgDAAO
is different from that of the tyrosine resi...