Báo cáo y học: " Cellular and molecular mechanisms of cigarette smoke-induced lung damage and prevention by vitamin c" ppsx

... M, Miyano Y, et al. Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy. Hepatology 1998;27:1711-1716. ... C, Berby F, Stuyver L, et al. Early detection of viral resistance by determination of hepatitis B polymerase mutations in patients treated by lamivudine for chronic...

Ngày tải lên: 03/11/2012, 09:41

... computed K a (the number of nonsynonymous substitu- tions per nonsynonymous site) and K s (the number of synon- ymous substitutions per synonymous site) for all gene pairs by a maximum likelihood ... genomes of yeast, Drosophila, and Caenorhabtidis elegans. However, the neutrality of K s was questioned by later studies [4-7]. Accordingly, Gu and cow- orkers [4] proposed t...

Ngày tải lên: 14/08/2014, 08:20

... presence of RANKL. Changes in cell morphology and induction of apoptosis were examined by scanning electron microscopy, whilst resorptive activity was determined by measuring the area of resorption ... alone. Cell lysates were then analysed by Western blotting for Mcl-1 and Bcl-2. The level of Mcl-2 or Bcl-2 was quantified by densito- metric analysis and expressed as a...

Ngày tải lên: 09/08/2014, 14:20

... (when organogenesis is beginning and pluripotency is being lost) are also expressed in hESCs, and that many of these genes are likely to be regulated by pluripotency-promoting trans- cription factors ... the entire period of organogenesis in human embryos [6]. Yet other studies have analyzed the trans- criptomes of human oocytes, hESCs and human pre- implantation embryos (bl...

Ngày tải lên: 09/08/2014, 20:22

... activation of TLR2 and 4 with peptidoglycan and LPS respectively leads to induction of SLPI. Finally, we confirmed that SLPI exerted an anti-inflammatory effect in adipocytes treated with LPS by causing ... highly expressed in adipocytes and many functional assays have shown that their activation evokes inflammatory responses that are accompanied by increased expression of man...

Ngày tải lên: 11/08/2014, 03:20

... an assay sensitivity of < 7 pg/ml and an inter assay and intra assay variation of < 10%. Statistical analyses All data were checked for normality and then analyzed using the GLM model analysis. ... adipo- cytes, activation of NFB and MAPK pathways in adipo- cytes by LPS is transient and rapidly returns to basal over time [20]. Although several mechanisms are behind...

Ngày tải lên: 11/08/2014, 06:22

... Vodovotz Y, Tyagi V, Barclay D, Philips BJ, Yoshimura N, Chancellor MB, Tyagi P: Multiplex analysis of urinary cytokine levels in rat model of cyclophosphamide-induced cystitis. Urology 2009, ... levels of NO 2 - / NO 3 - 6 h post-CYP, followed by a steady decline to levels Urinary profile and baseline levels of NO reaction productsFigure 1 Urinary profile and baseline levels...

Ngày tải lên: 11/08/2014, 08:22

... completely solved by this study, we conclude that the 30° head-down posi- tion and complete covering of the face by drapes (two manoeuvres that are frequently employed in anaesthesia, intensive care and ... SM, McDonough KH: Effects of anesthesia on pul- monary function. In Cardiopulmonary Physiology in Anesthesiology. Edited by Levitzky MG, Hall SM, McDonough KH. New York: McGr...

Ngày tải lên: 12/08/2014, 18:20

... between control and 5-day exposed (P = 0.538) and 20-day and 5-day exposed (P = 0.119) rats. ** Significantly different from control, 5-day and 20-day exposed rats and * sig- nificantly different ... control and 5-day exposed rats (P = 0.789). ** Significantly different from control, 5-day and 20-day exposed rats and * indicates significantly different from control and 1-da...

Ngày tải lên: 12/08/2014, 18:21

... efficiency of HIV-1 specific restriction. Ylinen and colleagues showed that HIV-2 particles are weakly restricted by human TRIM5α expressed in TE671 cells and efficiently restricted by rhesus ... restricted by human TRIM5αFigure 1 (A) VSV-G envelope and HIV-1 envelope protein pseudotyped viruses are equally restricted by human TRIM5α. Titration of HIV-1[VSV-G], HIV-1[NL4.3]...

Ngày tải lên: 13/08/2014, 09:20