Báo cáo y học: "15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases" ppsx

... immune systems provide a finely tuned regu- latory system required for health. Disturbances at any level can lead to changes in susceptibility to, and severity of, autoimmune /inflammatory disease. ... T 3 [70]. Neural pathways Sympathetic nervous system The sympathetic nervous system regulates the immune system at regional, local, and systemic levels. Immune organs including thymus, splee...

Ngày tải lên: 09/08/2014, 01:23

... number not for citation purposes) Journal of Inflammation Open Access Research 15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases Ratna ... we have previously shown that 15d-PGJ2 has an anti -inflammatory role in primary astrocytes [29]. This study reports for the first time that 15d-PGJ2 inhibits adhesio...

Ngày tải lên: 11/08/2014, 08:22

... there is hyperalgesia and/or allodynia only for mechanical stimuli, and not for heat [7]. Therefore "peripheral zone of burn injury" refers to the margins of the area of primary hyperalgesia/allody- nia. In ... mechanical stimulus is increased. In the area of secondary hyperalge- sia/allodynia, there is hyperalgesia and/or allodynia only for mechanical stimuli, and not for h...

Ngày tải lên: 11/08/2014, 08:22

... 28-day mortality. While a difference in 28-day mortality was suggested by the data, an intension to treat analysis was not performed and infectious morbidity and hospital length of stay were ... had significant effects on all study outcomes (mortality, secondary infections and LOS). Subgroup analysis by patient category revealed a reduction in secondary infections and LOS in ICU patien...

Ngày tải lên: 13/08/2014, 16:20

... Immunology, University of Rostock, Rostock, Germany 2 Institute of Pathology, University of Rostock, Rostock, Germany 3 Institute of Neurology, University of Rostock, Rostock, Germany 4 Section for ... disease, namely tissue destruction and synovial hyperplasia. In this study we examined the role of perforin (pfp), a key molecule of the cytotoxic death pathway that is expressed mainly in CD...

Ngày tải lên: 09/08/2014, 06:23

... pulmonary hyper tension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Soci ety (ERS), en dorsed by ... followed by 35 cycles of 95°C for 30 s, 51°C for 30 s and 72°C for 1 min, and a final extension at 72°C for 10 min; for Skp-2 was initiated by a 5 min denaturation step at 95°C, f...

Ngày tải lên: 12/08/2014, 13:22

... beyond the scope of this study; however the biological advantage to this type of response is not obvious. A more likely option is that the physical force imposed by compression physi- cally altered ... the airway epithelium to denudation and mechanical compression independently, they are closely linked both temporally and spatially in vivo [12,16]. A single study encompassing both types of ep...

Ngày tải lên: 12/08/2014, 14:20

... currently ongoing in our labora- tory. The inhibition of antiretroviral drug efficacy by estrogen may have implications for anti-HIV-1 drug therapies. The studies presented here put forth the ... concept that at any given plasma concentration of drug, the final efficacy may be significantly affected by the hormone status of the patient. Most likely, β-estradiol acts by modifying intrac- ell...

Ngày tải lên: 13/08/2014, 05:21

... care unit. Key messages • Hyperfibrinolysis may play a role in inflammatory response (IR) after cardiopulmonary bypass (CPB). • Inhibition of fibrinolysis with tranexamic acid may attenu- ate ... Investigación y Salud) 2202. References 1. Laffey JG, Boylan JF, Cheng DC: The systemic inflammatory response to cardiac surgery: implications for the anesthesiologist. Anesthesiology 2002,...

Ngày tải lên: 13/08/2014, 08:21

... Evidence for active Na + transport by cultured monolayers of pulmonary alveolar epithelial cells. Am J Physiol Cell Physiol 1983, 245:C78-C83. Key messages • The increased clearance of pulmonary oedema ... pul- monary edema caused by short periods of cyclic overinflation. J Appl Physiol 1992, 72:2081-2089. 19. Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS: Injurious ven- tilatory str...

Ngày tải lên: 13/08/2014, 08:21