Báo cáo y học: "Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro" pps
... purposes) of chondrocytes after exposure to PFE and IL-1β was deter- mined by Trypan blue exclusion assay. Determination of COX activity by EIA The COX-1 and COX-2 inhibitory assay was carried out using ... purposes) Journal of Inflammation Open Access Research Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2...
Ngày tải lên: 11/08/2014, 08:22
... proteins containing th e GAL4 DNA- binding domain and the c-Ju n activation domain (residues 1–223) in wild-type and mutant forms ( not phosphorylat- able by mutation of both serines 63 and 73 ... analysed by SDS/PAGE and the radioactivity was quantified directly using a FUJIBAS phosphorimager s ystem (Fuji). JNK phosphorylation w as induced in controls with 10 lgÆmL )1 of anis...
Ngày tải lên: 08/03/2014, 22:20
... eventually leading to complete loss of the articular surface and exposure of the underlying bone. These changes are almost always associated with severely impaired joint function and clinical symptoms ... intramuscularly) and xyla- zine (7 mg/kg intramuscularly). The rabbits were placed in the supine position and surgery was performed on the left knee. After shaving and steril...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Increased levels of circulating microparticles in primary Sjögren''''s syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity" pdf
... diseases and catalyzes hydrolysis of aminophos- pholipids, including PS, as well as phosphatidylcholine and phsophatidylethanolamine, all contained in microvesicles [16]. Plasma sPLA2 activity was ... studies of function are needed to understand the involvement of MPs in signalling pathways of remote cellular cross-talk in AIDs and how platelets are precisely involved i...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action" pot
... similarity clustered together (Figure 2c): rapamycin, calyculin A and wiskostatin. The similar- ity in these profiles resulted from inhibition of strains deleted for genes involved in intracellular ... for understanding drug action, including cell permeability and the potential interaction/inhibition of other proteins in a cellular context. In vivo chemical genomic assays ad...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "Genome sequence of the necrotrophic plant pathogen Pythium ultimum reveals original pathogenicity mechanisms and effector repertoire." doc
... inhibitors (serine and cysteine), NPP1-like proteins (toxins), cellulose-binding elicitor lectin (CBEL)-like proteins with carbohydrate binding domains, elicitins and elicitin-like proteins, secreted ... set of can- didate b-1,3-glucan synthases likely involved in synthesis of cell wall b-glucans and in the metabolism of mycola- minaran, the main carbon storage compound in P...
Ngày tải lên: 09/08/2014, 20:22
Báo cáo y học: ": Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility" docx
... ted only in carcino- mas, in 45 cases the transcript was expressed only in carcinomas and not in normal tissue. This may be due to activation of signaling pathways not expressed in normal skin, ... gene expression in tumor tissue, higher levels of expression in papillomas from resistant mice carrying t he SPRET/Ei allele, and the documented biological activity of gra...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: " Conservative treatment of a left atrial intramural hematoma after left atrial thrombus resection and concomitant mitral valve replacement - case report" ppsx
... echocardiographic imaging in the de tection and monitoring of this unexpected event. Consent Written informed consent was obtained from the patient for publication of this case report and any accompany- ing images. ... resection and the beneficial role of perioperative echocardiography in detecting and monitoring this event. Case presentation A 76-year-old woman with a histo...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity" potx
... amount of cytokine for each sample was determined in duplicate. Using a standard curve provided in the kit, the concentration of cytokines was determined for each sample. Cytokine array Human inflammation ... T-cell responses [6]. Finally, DCs are the source of secretion of very potent pro-inflammatory cytokines and chemokines. The hall-mark cytokines involved in initiation...
Ngày tải lên: 11/08/2014, 06:22
Báo cáo y học: " Mild episodes of tourniquet-induced forearm ischaemia-reperfusion injury results in leukocyte activation and changes in inflammatory and coagulation markers" pptx
... phagocytic leukocyte. Both monocytes and neutrophils have been implicated to play a key role in the development of ischaemia-reperfusion injury, where they are intrinsically involved in leukocyte-endothelial ... and neutrophils have been implicated to play a key role in the development of ischaemia-reperfusion injury, where they are intrinsically involved in leukocyte-endothel...
Ngày tải lên: 11/08/2014, 08:21