Báo cáo y học: "The tripeptide feG inhibits leukocyte adhesion" pot
Báo cáo y học: "The tripeptide feG inhibits leukocyte adhesion" pot
... AccessResearchThe tripeptide feG inhibits leukocyte adhesionRonald D Mathison*, Emily Christie and Joseph S DavisonAddress: University of Calgary, Faculty of Medicine, Department of Physiology and Biophysics, ... AbstractBackground: The tripeptide feG (D-Phe-D-Glu-Gly) is a potent anti-inflammatory peptide thatreduces the severity of type I immediate hypersensitivity reactions, and inhibits neutrophilchemotaxis ... The tripeptide FEG ameliorates systemic inflammatory responses to rat intesti-nal anaphylaxis. BMC Physiol 2002, 2:13.11. Bao F, John SM, Chen Y, Mathison RD, Weaver LC: The tripeptide phenylalanine-(D)...
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Báo cáo y học: "The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes" ppt
... chondro-cytes that respond to biochemical and physical stimuli tomaintain this tissue. Cartilage is primarily composed of type IIcollagen and proteoglycan, which are synthesized by thechondrocytes. ... Therapy Vol 5 No 5 Elliott et al.teoglycan, is correlated with disease severity [6]. Further-more, whereas lost proteoglycan is replaced rapidly,degraded collagen is resynthesized very slowly ... bothmolecules are similarly affected by CDDO.CDDO dose–response study in human primarychondrocytesTo examine the effects of increasing doses of CDDO inhuman primary chondrocytes, cells were preincubated...
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Báo cáo y học: "The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity" ppt
... enough time for lymphocyteclones to fully proliferate and destroy the pathogen.Unfortunately, it is likely that only studies with humanswould conclusively prove or disprove this hypothesis.Animal ... increases after the lymphocytehas already been stimulated by antigen, it will have noeffect on the lymphocyte at physiological levels. But if cor-tisol rises before the lymphocyte is presented ... " CD8 lymphocytes after 4 hours of hyperinsuline-mia in the normal subjects had a sharp reduction ininsulin-supported lymphocyte mediated cytotoxicity"[74]. A lymphocyte cannot respond...
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Báo cáo y học: " The Psychiatric Case Register Middle Netherlands" pot
... JJ, Mulder CL: Case registers in psychiatry:do they still have a role for research and service monitoring? Curr OpinPsychiatry 2008, 21:379-384.4. American Psychiatric Association: Diagnostic ... Center for Health Sciences and Primary Care, University MedicalCenter Utrecht, Utrecht, The Netherlands.2Clinical and Health Psychology,Utrecht University, Utrecht, The Netherlands.3Altrecht, ... security number (BSN). Thisrequires the use of a ‘third trusted party’ to protect theprivacy of patients in the case-register, which is cur-rently being explored.ConclusionsThe Psychiatric...
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Báo cáo y học: " The impact of mental illness on potentially preventable hospitalisations: a population-based cohort stu" ppt
... registration atstudy entry. Age is calculated from date of birth andstudy entry date. For MHCs, the study entry date was 1January 1990 for patients recorded in the MHR before 1January 1990, or the ... that there may be poten-tial problems in preventive/primary care in MHCs thatwarrant more in-depth analysis. Secondly , the lack ofdata on ambulatory services provided by private psychia-trists ... days and average length of stay for potentially preventable hospitalisations by studycohort, PPH category and condition, 1 January 1990 to 30 June 2006PPH category/condition Discharges inMHCs(n...
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Báo cáo y học: " The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease" ppt
... andantichymotrypsin are upregulated mainly by a later wave ofcytokines such as those of the IL-6 family (IL-6 and onco-statin M), suggesting that these different inhibitors mightbe physiologically ... anti-HNEmonocyte inflammatory potentialGene therapy potential Currently being explored Adenovirus-elafin protects against lung injury(rodent model)HNE = neutrophil elastase.Respiratory Research ... antileukoprotease(SKALP) [2•]. They are synthesized and secreted locally atthe site of injury and are produced in response to primarycytokines such as IL-1 and TNF; they might therefore bepart of...
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Báo cáo y học: "The ins and outs of translation" potx
... is controlled by the cytoplasmicpolyadenylation element-binding protein (CPEB). DuringX. laevis oocyte maturation and early embryonic divisions,recruitment of the poly(A) polymerase GLD-2 to ... facilitated by a glutamine in the conserved GGQmotif in release factors. Interestingly, the ribosome-recycling step differs markedly between prokaryotes andeukaryotes. In prokaryotes, recycling ... Mago, Y1 4, RNA and ATP) determinedby her laboratory. The NMD pathway surveys mRNA duringhttp://genomebiology.com/2007/8/12/321 Genome Biology 2007, Volume 8, Issue 12, Article 321 Clancy et...
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Báo cáo y học: "The latest buzz in comparative genomics" potx
... uniqueopportunity to systematically investigate the molecular evo-lution of two genomes from the same genus. The compara-tive approach enables evolutionary biologists to studyprecisely the types of ... 2000,287:2185-2195.2. Dobzhansky T: Genetics and the Origin of Species. New York: Colum-bia University Press; 1937.3. Lewontin RC, Hubby JL: A molecular approach to the study ofgenic heterozygosity in natural ... America. Dobzhansky believed thatthe genetics of speciation could be successfully understoodonly by studying natural genetic variation within popula-tions, and he and others spent years developing...
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Báo cáo y học: "The wisdom, and madness, of crowds" pot
... author of amonthly column in Genome Biology modeled after anamusing column in Current Biology penned by Sydneyhttp://genomebiology.com/2008/9/11/112 GenomeBBiioollooggyy2008, Volume 9, ... encyclopedia encompassing all subjects,written not by a panel of chosen experts but by teams ofpeople interested in the subjects and subsequently updatedand amended by anybody has been wildly ... almost all of its articles can be editedby anyone who can access the Wikipedia website. Launchedin January 2001 by Jimmy Wales and Larry Sanger, it iscurrently the largest and most popular general...
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Báo cáo y học: "The secret(ion) life of worms" pot
... function or Gene Ontology term tohelp reveal their role in the nematode’s life cycle. Theproteins identified include glycolytic enzymes and potentialimmunomodulatory proteins.That the different ... to becytosolic in the nematode [9], but the LC-MS-MS analysis[5] places it firmly in the secretome. This adds support toprevious hypotheses that root-knot nematodes and rhizobialsymbionts ... different life stages have very different secretionprofiles indicates that parasitism by Brugia is a dynamicprocess that is tightly linked to the life cycle. Many moresecreted proteins were...
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