... production of cytokines can signifi-cantly increase the risk and extent of brain injury [5,24]. In terms of a systemic inflammatory response, increasedserum levels of different cytokines and che mokines ... managed in accor-dance with the guidelines of the University Schleswig-Holstein, Campus Kiel, Germany, and the Utstein-styleguidelines [8]. All animals received human care in com-pliance with ... B: Anti-inflammatory effects of sevofluraneand mild hypothermia in endotoxemic rats. Acta Anaesthesiol Scand 2007,51:893-899.47. Lee HT, Kim M, Jan M, Emala CW: Anti-inflammatory and antinecroticeffects...