Báo cáo y học: "Treatment of experimental colitis in mice with LMP-420, an inhibitor of TNF transcription" pptx

... C57BL/6 mice by 3 cycles of 5 days of 3% DSS in drinking water, followed by 16 days of plain water. LMP-420 therapy was given parenterally (i.p.) or orally in food to groups of 5 mice, beginning ... and TNF- RII during induction of chronic DSS colitisFigure 6 Stool levels of TNF and TNF- RII during induction of chronic DSS colitis. Levels of TNF (panel A) and...

Ngày tải lên: 11/08/2014, 08:21

... brain stem of hypoxic neonatal rats: Role of glucose, oxygen and epinephrine resuscitation Thoppil R Anju, Sadanandan Jayanarayanan and Cheramadatikudiyil S Paulose * Abstract Background-: Hypoxia ... an increase in the log (EC 50 )-1 indicating a shift in high affinity towards low affinity. Ki(L) also showed an increase in hypoxic neonatal rats with an increase in log (EC...

Ngày tải lên: 10/08/2014, 05:21

... glutathione-binding domain sug- gesting its role in the metabolism and maintenance of GSH levels in intact cells [20,22]. Since GSH is one of the major antioxidants of the airways, it can be hypothesized that ... samples with Zymed Rabbit Isotype Control and PBS, and stained with AEC (Zymed Laboratories Inc.) and thereafter with Mayer's haematoxylin. Western blot analysis...

Ngày tải lên: 12/08/2014, 15:20

... and MEP start to decrease. The main finding of this work is that airway obstruction may be closely associated with decreased respiratory pres- sures in patients with COPD. In fact, both MIP and ... state of respiratory muscles, thus providing clinicians with a further and helpful tool in monitoring the evolution of COPD. Background In several diseases, the evaluation of...

Ngày tải lên: 12/08/2014, 15:21

... or alternate sources of asthma care. Statistical analysis In a previous analysis of pulmonary and allergy specialist care, the severity -of- asthma score was associated with an increased risk of hospitalization ... baseline interview. The majority of participants (97%) also reported having health insurance covering outpatient visits for asthma. Approximately one-third of subje...

Ngày tải lên: 12/08/2014, 18:20

... are underestimating the use of CXCR4 by dual-tropic viruses in the brain. In [19], a concordance rate of 91% was obtained between genotypic and phenotypic assays in a clinical setting of 103 patients. In ... the SVM with a linear kernel achieves a con- cordance of 86.5% with the Trofile assay and a concord- ance of 79.7% with the TRT assay. Recombinant assays (Trofile...

Ngày tải lên: 13/08/2014, 05:21

... The system employed 274 physicians (6 years of training) and 837 nurses (2 years of training) and feldshers (3 years of training, akin to a physician’s assistant) The NK health system retains ... remaining in NK woul d likely increase the uptake of trainings the p artici- pants deem valuable to the community. • In sum, five key principles for planning training strategies were appl...

Ngày tải lên: 13/08/2014, 15:21

... production of cytokines can signifi- cantly increase the risk and extent of brain injury [5,24]. In terms of a systemic inflammatory response, increased serum levels of different cytokines and che mokines ... managed in accor- dance with the guidelines of the University Schleswig- Holstein, Campus Kiel, Germany, and the Utstein-style guidelines [8]. All animals received human...

Ngày tải lên: 13/08/2014, 20:21

... relaparotomy in patients with severe peritonitis [5].  eir initial study found no signifi cant diff erences in morbidity or mortality in the on-demand relaparotomy group as compared with the planned ... loss of productivity due to impaired ability to work).  ey found substantially lower resource utiliza tion in the on-demand group, Abstract Owing to an increasing focus o...

Ngày tải lên: 13/08/2014, 20:22

... ADH1 plays a dominant role in providing protection against large acute doses of vitamin A that are life-threatening, with ADH3 playing a significant secondary role, and ADH4 playing a very minor ... understanding into the roles of these enzymes in retinol turnover observed in the null mutant mice. ADH1 mRNA and protein is expressed at very high levels in mouse liver, intestine,...

Ngày tải lên: 31/03/2014, 15:20