Báo cáo y học: "Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass" pot

... Central Page 1 of 9 (page number not for citation purposes) Journal of Inflammation Open Access Research Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass Ulf ... application of the leukocyte inhibition module (LIM) in the cardiopulmonary bypass (CPB) limits overshooting leukocyte activity during cardiac surgery. We studied in...

Ngày tải lên: 11/08/2014, 08:21

... over-expres- sion of HEXIM1 resulted in a modest reduction of P-TEFb activity, thus the inhibition of Tat activity is unlikely due to a global reduction of cellular P-TEFb activity. To further investigate ... inhibition of Tat activity is unlikely due to a global inhibition of P-TEFb activity. Moreover, we found that basal transcription from the LTR sequences was largely...

Ngày tải lên: 13/08/2014, 09:21

... ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity introduced by the substitution, as is often the case in ribozyme inhibition by tetracyclines [33,39,43]. In ... is a speci®c target of erythromycin in vitro, suggest that the u se of erythromycin may h ave serious consequences: it may interfere with at least two major stages of eukary...

Ngày tải lên: 21/02/2014, 15:20

... complement activity remained after heat inactivation. Analysis of mTNF expression on T cells was performed by flow cytometry with anti-CD3-phycoerythrin, anti-CD4-phycoeryth- rin-cyanin-5.1 (Beckman ... these lymphocytes were presumably resting mem- ory T lymphocytes at the moment of blood collection. To ana- lyse the effect of TNF antagonists on the activation of anti- mycobacter...

Ngày tải lên: 09/08/2014, 08:22

... Pierotti MA: Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene. Proceedings of the National Academy of Sciences of the United States of America 2005, 102(41):14825-14830. 14. ... from potentially life- threatening symptoms including obesity, depression, infertility, and gastrointestinal abnormalities due to sub- clinical hypothyroidism. With...

Ngày tải lên: 11/08/2014, 08:21

... be constitutively expressed on human and mouse kidneys and TLR2 deficiency protects from the renal ischemia- Effect of AG-490 on kidney dysfunction induced by zymosanFigure 2 Effect of AG-490 on kidney dysfunction ... 3 Department of Physiology and Pharmacology "Vittorio Erspamer", Sapienza University of Rome, Italy Email: Petya Dimitrova* - petya_dimitrova@web.de; Valeriy...

Ngày tải lên: 11/08/2014, 08:22

... at any dose to maintain systolic blood pressure > 90 mmHg). Assay of endotoxin by endotoxin activity assay The EAA assay is described in detail elsewhere [22]. Briefly, a 2-ml sample of whole ... establish the role of endotoxaemia in the pathophysiology of critical illness. However, the ability to detect endotoxaemia reliably and rapidly may expedite the investigation of suspec...

Ngày tải lên: 12/08/2014, 18:21

... inhibition of ERK1/2 phosphorylation may be lying upstream of ERK1/2. Using a serine/threonine kinase SPA assay kit, the capability of NAMI-A to affect the ERK1/2 phosphoryla- tion activity was also ... Ventura 1,2 1 Department of Biomedical Sciences, Division of Biochemistry, Laboratory of Cardiovascular Research, 2 Division of Cell Biology, National Institute of Biostructu...

Ngày tải lên: 21/02/2014, 01:21

... treatment may cause a decrease in hyaluronan synthase activity by altering the lipid environment of membranes, especially the distribution of different cardiolipin species, surrounding hyaluronan synthase. Keywords: ... suggest that the inhibition of HA production was not caused by direct inhibition of HAS activity. Effect of MU on HAS activity in FM100 cells treated with MU Th...

Ngày tải lên: 08/03/2014, 09:20

... inhibition of platelet aggregation [6,7] and inhibition of inflammatory cytokine production in macrophages [8]. Curcumin has also been shown to affect the activity of a number of key enzymes such as cyclooxygenase ... Ca 21 ATPase activity by curcumin. (A) Ca 2þ -ATPase activity was measured as a function of [Ca 2þ ] free in the absence (B) and presence of 10 mM (W) and 25...

Ngày tải lên: 08/03/2014, 23:20