Báo cáo y học: " Alveolar macrophages lack CCR2 expression and do not migrate to CCL2" ppt

... reverse-transcriptase PCR, flow cytometry and migration analyses.Results: In contrast to peripheral blood monocytes, alveolar macrophages did not express theCCL2 receptor, CCR2, and did not migrate toward CCL2. ... values are always pre-sented as a ratio of chemokine receptor band intensity to GAPDH band intensity.Flow cytometric analysisIn preparation for flow cytometric analysis, freshly iso-lated peripheral ... differences in CCR2 mRNA expression, wecorrelated RNA expression with surface CCR2 expression on human monocytes and alveolar macrophages from thesame donor. Using flow cytometric analysis, freshly iso-lated...

Báo cáo Y học: The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier ppt

... BvgAS system does not onlycontrol expression of virulence related functions but alsoseveral housekeeping genes including cytochrome c and cytochrome d oxidases of the respiratory chain and severalputative ... [13]. PASdomains are known to monitor changes in redox potential,oxygen, the overall level of energy of a cell, and it wasrecently shown that they can bind small ligands such asFAD and ATP ... domainstructure that is very similar to those of the BvgS and EvgSproteins, but it lacks the extensive periplasmic domain.Because of to their striking structural similarities to ArcB and to...

Báo cáo y học: "Biological therapy in early arthritis – overtreatment or the way to go" pptx

... monoclonal antibody directed against TNF-α, wasgiven to patients with disease refractory to traditionalDMARD therapy and was found to suppress disease activity,improve the quality of life and decrease ... years, althoughshared epitope is strongly associated with anti-CCP antibody and may not be an independent predictor [58]. Recently, theassociation in many different populations betweenpolymorphism ... Smolen JS:Benefit of very early referral and very early therapy withdisease-modifying anti-rheumatic drugs in patients with earlyrheumatoid arthritis. Rheumatology (Oxford) 2004, 43:906-914.5....

Báo cáo y học: "Anti-tumour necrosis factor therapy and B cells in rheumatoid arthritis" pptx

... Therapy Vol 11 No 5 LeandroPage 2 of 2(page number not for citation purposes)leucocytes into inflamed joints), angiogenesis and tissue des-truction [7]. However, TNF and a related cytokine, lympho-toxin ... Dutcher PO, Hadley JA, Sanz I: Cutting edge:anti-tumor necrosis factor therapy in rheumatoid arthritisinhibits memory B lymphocytes via effects on lymphoid ger-minal centres and follicular dendritic ... Burmester GR, Berek C: Differential expression of chemokine receptors on peripheral blood Bcells from patients with rheumatoid arthritis and systemiclupus erythematosus. Arthritis Res Ther 2005,...

Báo cáo y học: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury" ppt

... mainly inflammatory cellseither derived from residen t microglia or infi ltratingmonocytes/leukocytes from the periphery b lood, and they could produce proinflammatory cytokines to increase the ... Dordrecht, London, Moscow:Kluwer Academic Publishers; 2007.36. Vito Turk JK, Guncar Gregor, Turk Boris: Lysosomal Cysteine Proteases and Their Protein Inhibitor New York, Boston, Dordrecht, London, ... DNA microarray and proteome analysis havebeen used to understand SCI-induced pathophysiology and to find potential therapeutic targets. Several studiesusing g enechip microarray have described...

Báo cáo y học: " Utility of clinical assessment, imaging, and cryptococcal antigen titer to predict AIDS-related complicated forms of cryptococcal meningitis" ppt

... Launay O, Lortholary O: Determinants ofdisease presentation and outcome during cryptococcosis: the CryptoA/Dstudy. PLoS Med 2007, 4:e21.8. Loyse A, Wainwright H, Jarvis JN, et al: Histopathology ... serum cryptococcalantigenemia and early mortality during antiretroviral therapy in ruralUganda. Trop Med Int Health 2007, 12:929-35.12. Graybill JR, Sobel J, Saag M, et al: Diagnosis and management ... 7:29http://www.aidsrestherapy.com/content/7/1/29Page 6 of 6Table 2 Demographic, Clinical and Laboratory Characteristics of Study Patients with AIDS-Related CryptococcalMeningitisAll patients withcryptococcal...

Báo cáo y học: "Cardiac arrest provoked by itraconazole and amiodarone interaction: a case report" ppt

... (+2)Yes (-1); no (+2); do not know or not done (0)6. Did the reaction reappear when a placebo was given? No (+1)Yes (-1); no (+1); do not know or not done (0)7. Was the drug detected in any ... decreased? Yes (+1)Yes (+1); no (0); do not know or not done (0)9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure? No (0)Yes (+1); no (0); do not know ... given? Yes (+2)Yes (+2); no (-1); do not know or not done (0)3. Did the adverse reaction improve when the drug was discontinued or a specific antagonist was given? Yes (+1)Yes (+1); no (0); do not...

Báo cáo y học: "Cholestatic jaundice, acute kidney injury and acute pancreatitis secondary to the recreational use of methandrostenolone: a case report" potx

... are readily available to the general publicover the internet and at public gyms, they are easilyobtained illegally, without a prescri ption. As a result,patients are less likely to report ... atrophy [4]. Stanozolol, another carbon-17-alkylated anabolic steroid, has been previously reported to cause severe cholestasis and acute renal failure in ayoung athlete [5]. Acute k idney injury ... his-tory of diffuse abdominal pain. Six weeks prior to theonset of the pain, he had a gradual onset of anorexia and a 20 pound weight loss. Our patient noticed darklycoloured urine and pale stools...

Báo cáo y học: "Synchronous perforation of a duodenal and gastric ulcer: a case report" ppt

... 20-day history of abdominal pain, vomiting and loss ofappetite. H e mentioned an eight kg weight loss ove r t helast 20 days, as he had been drinking almost exclusivelywater due to his symptoms. ... (tachypnea and tachycardia), along with the presenceof his acute abdomen led us to conclude that an emer-gency laparotomy constituted the treatment of choice. Inthe face of the emergency situation ... ther-apy. More specifically, we followed the protocol of tripletherapy: a proton pump inhibitor, amoxici llin and clari-thromycin were administered. After discharge our patientwas referred to...

Báo cáo y học: "Using internet enabled mobile devices and social networking technologies to promote exercise as an intervention for young first episode psychosis patients" docx

... anxiety [10,15] and negative symptom scores[10,14] among experimental participants compared to controls. One trial compared yoga therapy with exercisetherapy and found that while yoga therapy participantsshowed ... new research and better health and socialoutcomes for psychotic and related mood disorders. Can J Psychiatry2010, 55:486-497.Pre-publication historyThe pre-publication history for this paper ... study is to develop a prototype and test services delivered through intern et enabledmobile devices and social network techn ologies that aredesigned to e ncourage young people to engage inphysical...

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