Báo cáo y học: " Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids" ppt

... II and used in the assays of the antiradical and anti -lipoxygenase activity as standards. LOXs are the family of the key enzyme in the biosynthesis of leukotrienes that are postulated to play ... per- centage of enzyme activity inhibition. Radical scavenging assay The free radical scavenging capacity of the compounds tested, crude extract and fractions was d...

Ngày tải lên: 11/08/2014, 08:21

... Macroscopically, it is similar to CIA, with edema and deformity of the hindpaws; however, SIA is primarily an enthesopathy characterized by the proliferation of fibroblasts and the formation of periarticular enthesophytes ... find any microscopic or macro- scopic sign of OA or other pathology in a large number of nor- mal young and old (more than one year) mice of either str...

Ngày tải lên: 09/08/2014, 08:22

... neurodegeneration, and BACE-1 expression. Free Radic Biol Med 2006, 41:202-212. 48. Harkany T, Abraham I, Konya C, Nyakas C, Zarandi M, Penke B, Luiten PG: Mechanisms of beta-amyloid neurotoxicity: perspectives ... Biology 2010, 11:R56 http://genomebiology.com/2010/11/5/R56 Page 12 of 13 Out of this list, 99 pairs were deleted from any analyses described in this study, as we could...

Ngày tải lên: 09/08/2014, 20:22

... Raw 264.7 cells and synoviocytes, and SNP treated synovio- vytes. Activation of p38 was also significantly reduced in the LPS treated synoviocytes, and SNP treated Raw 264.7 cells and synoviocytes, but ... density of the protein bands was scanned by densitometry using MyImage (SLB, Seoul, Korea), and quantified by Labworks 4.0 software (UVP Inc., Upland, California). Transfectio...

Ngày tải lên: 11/08/2014, 08:22

... -592C and -819C alleles. Homozygos- ity for genotypes -592A/A and -819T/T was more strongly associated with sustained response than hetero- zygosity. Similarly, inheritance of the haplotype ATA was ... through T-lymphocyte pathways, the exact mechanism of action may be complicated. IL-10 may down-regulate MHC class I and class II expression, impeding both CTL and antibody response...

Ngày tải lên: 11/08/2014, 21:21

... erythrocytes. The erythrocytes were classified into; control erythrocytes, erythrocytes incubated with either 2 mM of PS or 2 mM of PQ, and erythrocytes incubated with combination of PS plus ... 001). Table 1: Hemolysis profile of control erythrocytes and erythrocytes exposed to either PRV or PQ at concentra- tion 2 m mole /L NaCl g/L % of erythrocytes hemolysis Control...

Ngày tải lên: 25/10/2012, 11:40

... with Lewy bodies and multiple system atrophy [25,26]. Synu- cleins lack cysteine or tryptophan residues. They have relatively unconstrained structures that are Ôrandom coilÕ according t o UVCD and ... versions of synucleins, together w ith the A30P and A53T mutants of a-synuclein that cause f amilial c ases of Parkinson's disease. Unfortunately the quality of s ome of the...

Ngày tải lên: 21/02/2014, 15:20

... closure catalysed by b-lactam synthetase (BLS/ORF3) [6–8]. Hydroxylation by clavaminic acid synthase (CAS/ORF5), followed by hydrolysis of the guanidino side-chain catalysed by proclavaminate amidino hydrolase ... glutamate and acetyl-coenzyme A, nor (detectably) the hydrolysis of N-acetylornithine. Mass spectrometry also revealed the reaction proceeds via acetylation of the b subunit...

Ngày tải lên: 08/03/2014, 22:20

... study, we newly synthesized and used four types of organic selenium compound: two types of selenoureas, sele- nourea A selenourea B, and two types of tertiary seleno- amides, selenoamide A and ... this study, however, we did not use the ESR method to examine production of other ROS, such as the hydro- xyl radical. Although it is not very likely that hydroxyl radical can be di...

Ngày tải lên: 23/03/2014, 07:20

... purpose of this study was to investigate the variations of paraoxonase activity and lipid profile in bipolar I patients, and the association of this activity with the sociodemographic, clinical and ... between this disease and PON1. This study aims to investigate both the variations of paraoxonase activity and lipid profile in bipolar I patients and the association...

Ngày tải lên: 09/08/2014, 01:21