Báo cáo y học: "The role of the purinergic P2X7 receptor in inflammation" pot

... reported on the role of cytokines in RP, either in patients or in the corresponding animal models. In the CIA model, several cytokines have been shown to play major roles in the inflammatory process, ... the most prominent cell types in inflammatory infiltrates of the tracheal cartilage. Macrophages are the major source of many cytokines, such as interleukin-...

Ngày tải lên: 09/08/2014, 01:24

... VEGF in the lung induces pulmonary edema with increased lung vascular permeability, the role of VEGF in the development of acute lung injury remains to be determined. Methods: To evaluate the role ... characteristic of ALI/ARDS in humans [25]. In this study, pre-incubation with VEGF significantly attenuated the increase in the permeability of the endothelia...

Ngày tải lên: 12/08/2014, 15:21

... development of acute hyperoxic lung injury within a few days. Upon hyperoxic exposure, the inducible nitric oxide synthase (iNOS) is activated by a variety of proinflammatory cytokines both in vitro ... a proinflammatory role in acute hyperoxic lung injury. Background Supplemental oxygen therapy is administered for the treatment of tissue hypoxia, most commonly in an inten-...

Ngày tải lên: 12/08/2014, 18:21

... involved in providing energy for Ca 2+ /Mg 2+ influx-efflux in the cardiac sarcolemma, opening the channel formed by the E-NTPase/E-NTPDase protein by altering the conformation of the sensors. The ... the E-type nucleotidase activity by weakening the monomer-monomer interac- tion and altering the tertiary and quaternary structures, result in the loss of holoenzym...

Ngày tải lên: 13/08/2014, 22:22

... of the country. The operational environment remains difficult to predict. In February 2006, the Ministry of Foreign Affairs, the Min- istry of Home Affairs and the Ministry of National Plan- ning ... and found an increasing frequency of HIV and AIDS related reporting since the beginning of 2004 [8]. The availability of condoms either through social market- ing or...

Ngày tải lên: 13/08/2014, 13:21

... cap- binding by eIF4E [54] indicating that the eIF4F complex will likely stay intact (note that the binding of either 4E-BP1 or eIF4G to eIF4E appears to be the determining factor in stabilizing the ... be a very valuable tool in studying the functional effects of eIF4E phosphorylation. The Mnks may of course have other roles in cellular physiology, and knock-outs of...

Ngày tải lên: 23/03/2014, 21:20

... level of c-Myc. Also, the contribution of Ras/Raf/ERK prevented the rapid degradation of c-Myc by phosphorylation of the serine 62 residue in the N-terminal of c- Myc [24]. They also found that the ... hypothesized that c-Myc plays a central role in TGF1 signaling for cell growth stimulation. Additionally, to examine the possibility of involvement of the MAP...

Ngày tải lên: 09/08/2014, 01:22

... critical, single alanine-substitution mutants of YgfZ were created in the fingerprint region. These YgfZ variants were then assessed for the ability to restore plumbagin resistance in the ΔygfZ strain. ... conception that YgfZ behaves in a mechanism different from that of SodA as to resolving the threat of plumb agin. One of the likely roles of YgfZ involved is possi...

Ngày tải lên: 10/08/2014, 05:21

... back pain and/or sciatica: this exerts an important impact on the quali ty of life, causing interfer- ence of sleep and enjoyment of life. Many clinical studies have compared t he efficacy of surgery ... 2009 of the Journal of Brachial Plexus and Peripheral Nerve Injury [1]. We congratulate the Jour nal for the interest in this topic. This innovative study demonstrated...

Ngày tải lên: 10/08/2014, 10:20