Báo cáo y học: "Early Inhibition of NF-κB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)" pot

... activation by plasma of five volunteers before and after five days intake of 200 mg mari-time pine bark extract (Pycnogenol)Figure 3 Inhibition of LPS-induced NF-κB activation by plasma of five volunteers ... before and after five days intake of 200 mg maritime pine bark extract (Pycnogenol)Figure 2 Inhibition of LPS-induced matrix metal...

Ngày tải lên: 11/08/2014, 08:21

... measures of severity – mean number of organ dysfunctions and APACHE II score – and two dynamic laboratory measures – serum creatinine and platelet count – were associated with 28-day mortality. Following ... University of Ottawa, The Ottawa Hospital, 1053 Carling Ave, Ottawa, ON, Canada, K 1Y4 E9 2 Departments of Anesthesiology, Medicine and Pharmacology, Associate Professor...

Ngày tải lên: 13/08/2014, 16:20

... modeling. BY performed data analysis after mathematical caculation using IPA and other bioinfor- matic tools. BY, KS, XY and ZC contributed to the experimen- tal designs. BY, KS and XY wrote experimental ... over-expression and activation of EGFR, IL1 and IL6 signal transduction pathways, mutation and altered activation of TFs p53, NF- κ B, AP-1, STAT3 and EGR1, ov...

Ngày tải lên: 14/08/2014, 08:20

... pathway. Independently of these pathways, protein kinase C (PKC) is able to phosphorylate E lk-1 directly. PKC is activated by diacylglycerol, which is formed by phospholipase C (PLC) mediated phosphatidylinositol ... Reinhard Kandolf 2 and H. Peter Rodemann 1 1 Section of Radiobiology and Molecular Environmental Research, Department of Radiotherapy, and 2 Department of Mole...

Ngày tải lên: 17/03/2014, 17:20

... assessed histologically 8 days after the onset of arthritis. Proteoglycan depletion was determined by safranin O staining. Expression of cytokines, receptor activator of NF-κB ligand, and c-Fos was evaluated ... Phar- macokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers. J Interferon Cytokine Res 2000, 20:857- 866. 28. Miyazaki T, Katagiri H, Kanegae Y, T...

Ngày tải lên: 09/08/2014, 01:23

... induced by NMDA. The inhibitory action of ketamine on NMDA-induced response was reversed by CHPG, DFB, and CDPPB, whereas the blockade of NMDA receptor by D-APV was restored by CHPG and CDPPB, ... with pre- treatment of NMDA before mGluR5 activation, the potentiation of the NMDA receptor and restoration of receptor barrier were only regulated by CHPG, but not by D...

Ngày tải lên: 10/08/2014, 05:21

... [6], and vice versa, the inhibition of GSK3 by lithium in the context of circadian rhythms is hardly a panacea for the therapy of affective mood disorders. Nevertheless, (i) the cyclical and episodic ... inhibition of GSK3 activity by kenpaullone, a known antagonist of GSK3 activity, as well as by lithium, a direct inhibitor of GSK3 and the most common treatment fo...

Ngày tải lên: 10/08/2014, 09:20

... tribes of South, Central, and North America. Both viruses may be transmitted from mother to child mostly by breastfeeding, by sexual inter- course, and by blood transfusion and the sharing of con- taminated ... University of West Indies, Jamaica V May/1992 Kumamoto, Japan 300 Kumamoto University, Japan VI May/1994 Absecon, New Jersey, USA 375 Dr. Stanley Weiss, University Me...

Ngày tải lên: 13/08/2014, 09:21

... peptides The cyclic RGD-peptide c(RGDf(෈-S-acetylthioacetyl)K) and the RAD analogue c(RADf(෈-S-acetylthioacetyl)K), hereafter referred to as RGDpep and RADpep, respectively, were pre- pared by Ansynth ... the entry pathway of non-modified virus is exclusively CAR- dependent. On the other hand, the transduction of HUVECs by AddnIκB-PEG-RGD was significantly inhibited by the pres-...

Ngày tải lên: 09/08/2014, 07:20

... of Bioscience and Biotechnology, Faculty of Engineering, Graduate School of Natural Science and Technology, Okayama University, Japan; 2 Department of Biology, Faculty of Sciences, University ... also attenuated by this modi®cation. These results suggest that growth inhibition by ECP is dependent on cell type and is cytostatic. Keywords: cell cycle; colony formation; cyt...

Ngày tải lên: 17/03/2014, 17:20